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  • T39235Tos-O-C4-NH-Boc；Tos-O-C4-NH-BocTos-O-C4-NH-Boc；Tos-O-C4-NH-Boc

    Tos-O-C4-NH-Boc is an alkyl ether-based linker utilized for synthesizing PROTACs, including BSJ-03-204.

    价 格：￥电议型 号：T39235产 地：中国大陆

  • T39131Boc-NH-C4-BrBoc-NH-C4-BrBoc-NH-C4-Br

    Boc-NH-C4-Br is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T39131产 地：中国大陆

  • T38999Biotin-C4-amide-C5-NH2Biotin-C4-amide-C5-NH2Biotin-C4-amide-C5-NH2

    Biotin-C4-amide-C5-NH2 is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs).

    价 格：￥电议型 号：T38999产 地：中国大陆

  • T38726Chloroacetamido-C4-NHBoc；Chloroacetamido-C4-NHBocChloroacetamido-C4-NHBoc；Chloroacetamido-C4-NHBoc

    Chloroacetamido-C4-NHBoc is an alkyl/ether-based linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs).

    价 格：￥电议型 号：T38726产 地：中国大陆

  • T38602(E/Z)-Eltrombopag 13C4；(E/Z)-Eltrombopag 13C4(E/Z)-Eltrombopag 13C4|||(E/Z)-SB-497115 13C4；(E/Z)-Elt

    (E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia.

    价 格：￥电议型 号：T38602产 地：中国大陆

  • T382934-CPPC；化合物4-CPPC4-CPPC

    4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.

    价 格：￥电议型 号：T38293产 地：中国大陆

  • T37980N-methyl Leukotriene C4；N-methyl Leukotriene C4N-methyl Leukotriene C4；N-methyl Leukotriene C4

    Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4, however, is rapidly metabolized to LTD4 and LTE4, which makes the characterization of LTC4 pharmacology difficult. N-methyl Leukot

    价 格：￥电议型 号：T37980产 地：中国大陆

  • T37620Leukotriene C4 methyl ester；Leukotriene C4 methyl esterLeukotriene C4 methyl ester

    Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute all

    价 格：￥电议型 号：T37620产 地：中国大陆

  • T37599DA-JC4；DA-JC4DA-JC4；DA-JC4

    DA-JC4 is a compound with dual GLP-1/GIP receptor agonist properties. It is recommended for use in researching neurological diseases and investigating insulin signaling pathways[1][2][3].

    价 格：￥电议型 号：T37599产 地：中国大陆

  • T37564C4 Ceramide (d18:1/4:0)；C4 Ceramide (d18:1/4:0)C4 Ceramide (d18:1/4:0)|||Cer(d18:1/4:0)；C4 Ceramide

    C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing

    价 格：￥电议型 号：T37564产 地：中国大陆

  • T3749211-trans Leukotriene C4；11-trans Leukotriene C411-trans Leukotriene C4；11-trans Leukotriene C4

    11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils, but not in human neutrophils or RBL-1 cells. It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum. In a radioligand binding assay using guinea pig ileum

    价 格：￥电议型 号：T37492产 地：中国大陆

  • T37202CC4；CC4CC4；CC4

    High affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively). Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for human α3β4 and rat α7 receptors respectively). Stimulates dopamine release from striatal slices in vitro. Attenuates nicotine-induced self-administration and conditional place preference in rats.

    价 格：￥电议型 号：T37202产 地：中国大陆

  • T37069Pyribencarb；吡菌苯威ZINC43065336；吡菌苯威|||ZINC43065336

    Pyribencarb, a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi. Acting as a potent Qo inhibitor of cytochrome b, Pyribencarb demonstrates particular efficacy against Botrytis cinerea and Sclerotinia sclerotiorum.

    价 格：￥电议型 号：T37069产 地：中国大陆

  • T36408Rhein-13C4；Rhein-13C4Rhein-13C4；Rhein-13C4

    Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i

    价 格：￥电议型 号：T36408产 地：中国大陆

  • T36280VH 032 amide-alkylC4-acid；VH 032 amide-alkylC4-acidVH 032 amide-alkylC4-acid；VH 032 amide-alkylC4-ac

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36280产 地：中国大陆

  • T36273VH 101 phenol-alkylC4-amine；VH 101 phenol-alkylC4-amineVH 101 phenol-alkylC4-amine；VH 101 phenol-alk

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36273产 地：中国大陆

  • T36269(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride；VH 032 phenol-alkylC4-amineVH 032 phenol-alkylC4-amine；VH

    Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 1 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36269产 地：中国大陆

  • T35790Palmitic acid-1,2,3,4-13C4；Palmitic Acid-13C (C1, C2, C3, and C4 labeled)Palmitic Acid-13C (C1, C2,

    Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula

    价 格：￥电议型 号：T35790产 地：中国大陆

  • T35469A 410099.1 amide-alkylC4-amineA 410099.1 amide-alkylC4-amineA 410099.1 amide-alkylC4-amine

    Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T35469产 地：中国大陆

  • T34558SC-48274；化合物 T34558SC 48274|||SC48274；SC 48274|||SC48274

    SC-48274 is a novel anxiolytic. SC-48274 has anxiolytic activity of the same potency as buspirone and repeated-dose administration is needed to induce anxiolytic acitivity.

    价 格：￥电议型 号：T34558产 地：中国大陆

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