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T62670Cemdomespib;化合物 CemdomespibCemdomespib
Cemdomespib (KU-596) is a potent second-generation Hsp90 modulator. cemdomespib induces a heat shock response, induces Hsp70 levels and has neuroprotective effects. cemdomespib has been shown to improve sensory deficits in models of diabetic peripheral neuropathy.
价 格:¥电议型 号:T62670产 地:中国大陆
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T4627SPI--112Me;化合物SPI--112MeSPI--112Me
SPI--112Me, a prodrug of SPI-112, preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by more than 20-fold in cell-free assays.
价 格:¥电议型 号:T4627产 地:中国大陆
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T41140Eesperamicin A1;Eesperamicin A1Eesperamicin A1;Eesperamicin A1
Esperamicin A1, an exceedingly potent antitumor antibiotic, is derived from Actinomadura verrucosospora cultures. This compound plays a crucial role in antitumor research.
价 格:¥电议型 号:T41140产 地:中国大陆
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T40514ESP 15228;化合物 ESP 152282,2,14,14-Tetramethyl-8-oxopentadecanedioic acid;2,2,14,14-Tetramethyl-8-oxop
2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid is a ketone compound, compound example II-9. 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid can be used for the research of cardiovascular diseases, dysproteinemias, dyslipidemias, and glucose metabolism disorders.
价 格:¥电议型 号:T40514产 地:中国大陆
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T40173Spiropyran hexyl methacrylate;Spiropyran hexyl methacrylateSpiropyran hexyl methacrylate
Spiropyran hexyl methacrylate is a compound utilized to create a spiropyran-based polymeric hydrogel, specifically to enable light-activated mechanical actuation.
价 格:¥电议型 号:T40173产 地:中国大陆
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T3S2312Poncirin;枸橘苷Isosakuranetin-7-neohesperidoside;枸橘苷|||Isosakuranetin-7-neohesperidoside
1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enhances osteoblast differentiation in mesenchymal stem cellsincreased bone mineral density, and improves trabecular microarchitecture likely reflect increases bone formation and decreases bone resorption in GIO mice.
价 格:¥电议型 号:T3S2312产 地:中国大陆
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T39983SPR206 acetate;SPR206 acetateSPR206 acetate
SPR206 acetate is a polymyxin analog that exhibits antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. By interacting with the outer membrane of the bacterium, SPR206 acetate effectively combats bacterial infections. Notably, SPR206 acetate demonstrates significant efficacy with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301.
价 格:¥电议型 号:T39983产 地:中国大陆
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T39593SPOP-IN-6b hydrochloride;SPOP-IN-6b hydrochlorideSPOP-IN-6b hydrochloride
SPOP-IN-6b hydrochloride is a highly effective inhibitor of speckle-type POZ protein (SPOP), exhibiting an IC50 value of 3.58 μM.
价 格:¥电议型 号:T39593产 地:中国大陆
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T39439Seclidemstat mesylateSeclidemstat mesylateSP-2577 mesylate
Seclidemstat mesylate (SP-2577) is a highly effective and reversible inhibitor of KDM1A (LSD1), with a Ki of 31 nM and an IC 50 of 13 nM. It demonstrates significant potential in promoting antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, while also exhibiting inhibitory effects on virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate is a valuable tool for studying Ewing Sarcoma in research settings.
价 格:¥电议型 号:T39439产 地:中国大陆
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T39173Varespladib sodium;伐瑞拉迪钠;伐瑞拉地钠LY315920 sodium;LY315920 sodium|||伐瑞拉迪钠;伐瑞拉地钠
Varespladib sodium (LY315920 sodium) is a highly potent and selective inhibitor of group IIA secretory phospholipase A2 (sPLA2), with an IC50 of 9 nM. It demonstrates significant inhibitory activity against sPLA2 in serum samples from multiple species, including rat, rabbit, guinea pig, and human, with IC50 values of 8.1 nM, 5.0 nM, 3.2 nM, and 6.2 nM, respectively.
价 格:¥电议型 号:T39173产 地:中国大陆
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T38577Remdesivir O-desphosphate acetonide impurity;Remdesivir O-desphosphate acetonide impurityRemdesivir
Remdesivir O-desphosphate acetonide impurity is a contaminant found in Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue known for its potent antiviral properties, particularly in inhibiting SARS-CoV-2 (COVID-19) infection in vitro.
价 格:¥电议型 号:T38577产 地:中国大陆
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T3799Isorhamnetin-3-O-neohespeidoside;异鼠李素-3-O-新橙皮苷Isorhamnetin 3-O-neohesperidin|||Isorhamnetin 3-O-neoh
Isorhamnetin-3-O-neohespeidoside (Calendoflavoside) is a flavonol glycoside extract used as an anti-oxidant.
价 格:¥电议型 号:T3799产 地:中国大陆
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T37657Mitochondrial respiration-IN-1 hydrobromide;Mitochondrial respiration-IN-1 hydrobromideMitochondrial
Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial inhibitor (IC50=8.8 mg/mL). Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets[1].
价 格:¥电议型 号:T37657产 地:中国大陆
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T36436Spergualin trihydrochloride;Spergualin trihydrochlorideSpergualin trihydrochloride
Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2[1].
价 格:¥电议型 号:T36436产 地:中国大陆
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T3625Bempedoic acid;化合物ETC1002ETC1002|||ESP-55016|||ETC 1002|||ETC-1002;ETC1002|||ESP-55016|||ETC 1002|||
Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid(ETC1002) is absorbed rapidly in the small intestine and enters the liver through cell surface receptors different from those transporters that selectively take up statins. Bempedoic acid(ETC1002) is a regulator of lipid and carbohydrate metabolism.
价 格:¥电议型 号:T3625产 地:中国大陆
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T34921L1Tresperimus TFA;曲培莫司三氟乙酸盐Tresperimus TFA(160677-67-8 Free base);Tresperimus TFA(160677-67-8 Free bas
Tresperimus TFA can be used as an immune agent and can be used to study retinitis.
价 格:¥电议型 号:T34921L1产 地:中国大陆
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T34921LTresperimus HCl;化合物 T34921LTresperimus trihydrochloride|||LF08-0299 trihydrochloride|||LF 08-0299 tr
Tresperimus HCl can induce tolerance after the short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model.
价 格:¥电议型 号:T34921L产 地:中国大陆
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T34921Tresperimus;化合物 T34921LF08-0299|||LF 08-0299|||LF-08-0299;LF08-0299|||LF 08-0299|||LF-08-0299
Tresperimus can induce tolerance after the short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model.
价 格:¥电议型 号:T34921产 地:中国大陆
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T34696Spirapril HCl;化合物 T34696BRN4277924|||BRN-4277924|||BRN 4277924|||Spiraprilum|||Spirapril|||Espirapri
Spiropril is an ACE inhibitor antihypertensive drug, which belongs to the bicarboxyl group of ACE inhibitors and is used in the treatment of hypertension.
价 格:¥电议型 号:T34696产 地:中国大陆
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T3386Kaempferitrin;山奈苷Lespedin|||Kaempferol|||Lespenephryl|||Lespenefril|||Kaempferol 3,7-dirhamnoside;Le
Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucose-metabolizing enzymes, promotes glucose homeostasis. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes, macrophages, PBMC and NK cells. Kaempferitrin induces cytotoxic effects to include: cell cycle arrest in G1 phase and apoptosis via th
价 格:¥电议型 号:T3386产 地:中国大陆