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T7332(E)-2-Decenoic acid;反式-2-癸烯酸trans-2-Decenoic acid;trans-2-Decenoic acid|||反式-2-癸烯酸
(E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees.
价 格:¥电议型 号:T7332产 地:中国大陆
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T7309TAS-103 dihydrochloride;化合物TAS-103 (dihydrochloride)TAS-103 (dihydrochloride)|||BMS-247615 dihydroch
TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
价 格:¥电议型 号:T7309产 地:中国大陆
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T71549RKS-262;化合物 RKS-262RKS-262
RKS262 is a specific cyclin/CDK inhibitor. RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. In a NCI(60) cell-line assay RKS262 exhibited significant cytotoxicity in ovarian cancer cells and a variety of other cell lines exceeding effects of commercial drugs such as cisplatin, 5-FU, cyclophosphamide or sapacitabine. Various leukemia cell-lines were most sensitive (GI(50):?~?10 nM) while several
价 格:¥电议型 号:T71549产 地:中国大陆
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T7152Ravuconazole;雷夫康唑BMS-207147|||ER-30346;立福康唑|||雷夫康唑|||BMS-207147|||ER-30346
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T71504MLS-2384;化合物 MLS-2384MLS-2384
MLS-2384 is a dual JAK/Src kinase inhibitor, suppressing growth of diverse cancer cells.
价 格:¥电议型 号:T71504产 地:中国大陆
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T70929Naldemedine tosylate;化合物 Naldemedine tosylateS-297995 tosylate;S-297995 tosylate
Naldemedine tosylate (S-297995) is an orally active μ-opioid receptor antagonist (PAMORA) with high binding affinities (K_i = 0.34, 0.43, 0.94 nM) and potent antagonist activities (IC_50 = 25.57, 7.09, 16.1 nM) towards human recombinant μ-, δ-, and κ-opioid receptors, respectively. It is utilized in research on opioid-induced constipation (OIC). Additionally, Naldemedine tosylate is anticipated to interact with the 3CL proenzyme encoded by the SARS-CoV-2 genome.
价 格:¥电议型 号:T70929产 地:中国大陆
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T70385CGS-27023A HCl;化合物 CGS-27023A HClCGS-27023A HCl
CGS-27023A is a novel matrix metalloproteinase inhibitor.
价 格:¥电议型 号:T70385产 地:中国大陆
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T70285BMS-200;化合物 BMS-200BMS-200
BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.
价 格:¥电议型 号:T70285产 地:中国大陆
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T70004APS-2-79;化合物 APS-2-79APS-2-79
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
价 格:¥电议型 号:T70004产 地:中国大陆
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T68227BMS-214662 HCl;化合物 BMS-214662 HClBMS-214662 HCl
BMS-214662 is a Farnesyltransferase inhibitor , is also a nonsedating benzodiazepine derivative with potential antineoplastic activity. BMS-214662 inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction, which may result in the inhibition of Ras function and apoptosis in susceptible tumor cells. This agent may reverse the malignant phenotype of H-Ras-transformed cells and has been shown to be active against tumor cell
价 格:¥电议型 号:T68227产 地:中国大陆
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T67819DS-2969;化合物 DS-2969DS-2969
DS-2969 is a compound that has antibacterial activity.
价 格:¥电议型 号:T67819产 地:中国大陆
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T6760APS-2-79 hydrochloride;化合物APS-2-79APS-2-79 HCl|||APS-2-79;APS-2-79 HCl|||APS-2-79
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
价 格:¥电议型 号:T6760产 地:中国大陆
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T66777trans-2-Bromocinnamic Acid;化合物 trans-2-Bromocinnamic Acidtrans-2-Bromocinnamic Acid
trans-2-Bromocinnamic Acid is a useful organic compound for research related to life sciences. The catalog number is T66777 and the CAS number is 7345-79-1.
价 格:¥电议型 号:T66777产 地:中国大陆
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T66121Ketoconazole Intermediate 1e;酮康唑中间体1e(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-di
Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4- methylbenzenesulfonate) is a ketoconazole intermediate.
价 格:¥电议型 号:T66121产 地:中国大陆
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T66085cis-BBD;化合物 cis-BBD(cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl benzoate;(ci
cis-BBD can be used antifungal studies.
价 格:¥电议型 号:T66085产 地:中国大陆
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T6356(R)-Nepicastat HCl;盐酸内匹司他RS-25560-198 HCl;RS-25560-198 HCl|||盐酸内匹司他
(R)-Nepicastat HCl (RS-25560-198 HCl), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
价 格:¥电议型 号:T6356产 地:中国大陆
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T6267Lomitapide;洛美他派AEGR-733|||BMS-201038;AEGR-733|||洛美他派|||BMS-201038
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.
价 格:¥电议型 号:T6267产 地:中国大陆
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T6233Entinostat;恩替诺特SNDX-275|||MS-275;恩替诺特|||SNDX-275|||MS-275
Entinostat (MS-275) (MS-275) is an inhibitor of HDACs that inhibits HDAC1 and HDAC3 (IC50s: 0.18/0.74 μM).
价 格:¥电议型 号:T6233产 地:中国大陆
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T62209HS-276;化合物HS-276HS-276
HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM). HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA).
价 格:¥电议型 号:T62209产 地:中国大陆