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T6208AS-252424;化合物AS-252424AS-252424
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
价 格:¥电议型 号:T6208产 地:中国大陆
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T62054D4R antagonis-2;化合物 D4R antagonis-2D4R antagonis-2
D4R antagonist-2 is a potent and selective D4R antagonist (IC50= 6.52 μM). D4R antagonist-2 displays favorable in vitro PK parameters and exhibits good brain penetration. D4R antagonist-2 has the research potential in Parkinson’s disease.
价 格:¥电议型 号:T62054产 地:中国大陆
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T62037BNS-22;化合物 BNS-22BNS-22
BNS-22 is a catalytic inhibitor of DNA topoisomerase II ( TOP2 ). BNS-22 shows the IC 50 values of 2.8 μM and 0.42 μM for human TOP2α and TOP2β, respectively. BNS-22 induces abnormal division and shows anti-proliferative activity.
价 格:¥电议型 号:T62037产 地:中国大陆
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T61430S-2E;化合物 S-2ES-2E
S-2E is a compound that functions as an orally active, noncompetitive inhibitor of both HMG-CoA reductase and acetyl-CoA carboxylase. It exhibits an anti-hyperlipidemic action, making it suitable for studying conditions such as familial hypercholesterolemia and mixed hyperlipidemia [1] [2].
价 格:¥电议型 号:T61430产 地:中国大陆
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T60523Agomelatine hydrochloride;盐酸阿戈美拉汀S-20098 hydrochloride;S-20098 hydrochloride
Agomelatine hydrochloride (S-20098 hydrochloride) (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki of 0.1 nM for CHO-hMT1, 0.06 nM for HEK-hMT1, 0.12 nM for CHO-hMT2, and 0.27 nM for HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective antagonist of a 5-HT2C receptor with pKis of 6.4 and 6.2 for native (porcine) and cloned, human 5-HT2C receptors, respectively [2].
价 格:¥电议型 号:T60523产 地:中国大陆
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T60012HS-243;化合物HS-243HS-243
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
价 格:¥电议型 号:T60012产 地:中国大陆
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T5588cis,cis-Muconic acid;顺式-已二烯二酸cis,cis-Muconate|||cis,cis-2,4-Hexadienedioic acid;顺式-已二烯二酸|||cis,cis-M
cis,cis-Muconic acid (cis,cis-2,4-Hexadienedioic acid) is a naturally-occurring organic acid. It is used in the manufacture of several widely-used consumer plastics. Its microbial production via extending the shikimate pathway has been reported.
价 格:¥电议型 号:T5588产 地:中国大陆
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T5261(E)-Oct-2-enoic acid;2-辛烯酸trans-2-Octenoic acid|||2-Octenoate|||2-Octenoic acid;trans-2-Octenoic aci
(E)-Oct-2-enoic acid (2-Octenoate) is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma.
价 格:¥电议型 号:T5261产 地:中国大陆
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T5246Trans-?2-?butene-?1,?4-?dicarboxylic acid;反式-2-丁烯-1,4-二甲酸trans-2-Butene-1,4-dicarboxylic Acid|||3-He
Trans-?2-?butene-?1,?4-?dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders The urinary excretion of Trans-?2-?butene-?1,?4-?dicarboxylic acid is increased in conditions of augmented mobilization of fatty acids or inhibited fatty acid oxidation.
价 格:¥电议型 号:T5246产 地:中国大陆
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T4967NPS-2143 hydrochloride;化合物NPS-2143 HCLNPS-2143 HCL;2-氯-6-[(2R)-3-[[1,1-二甲基-2-(2-萘基)乙基]氨基]-2-羟基丙氧基]苯腈
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
价 格:¥电议型 号:T4967产 地:中国大陆
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T4454Traumatic Acid愈伤酸Dodec-2-Enedioic Acid|||2E-Dodecenedioic Acid|||愈伤酸|||Trans-2-Dodecenedioic Acid
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus.
价 格:¥电议型 号:T4454产 地:中国大陆
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T4451LEstramustine phosphate;化合物 T4451LLS 299|||NSC 89199|||NSC-89199|||LS-299|||LS299;LS 299|||NSC 89199|
Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.
价 格:¥电议型 号:T4451L产 地:中国大陆
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T4299AS-2444697;化合物AS-2444697AS-2444697
AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.
价 格:¥电议型 号:T4299产 地:中国大陆
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T4264Takinib;化合物TakinibEDHS-206;EDHS-206
Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).
价 格:¥电议型 号:T4264产 地:中国大陆
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T41233Cis-22a;化合物Cis-22aCis-22a
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
价 格:¥电议型 号:T41233产 地:中国大陆
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T40711H-D-Phe-Pip-Arg-pNA dihydrochloride;化合物H-D-Phe-Pip-Arg-pNA dihydrochlorideS-2238 dihydrochloride|||H
H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, H-D-Phe-Pip-Arg-pNA dihydrochloride is employed for the quantification of antithrombin-heparin cofactor (AT-III). The AT-III assay utilizing this substrate is characterized by its sensitivity, accuracy, and ease of implementation.
价 格:¥电议型 号:T40711产 地:中国大陆
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T40358Ensitrelvir fumarateEnsitrelvir fumarateS-217622 fumarate
Ensitrelvir (S-217622) fumarate is a novel orally active inhibitor, targeting the SARS-CoV-2 3CL protease (IC50 = 13 nM). It demonstrates non-covalent and non-peptidic characteristics. This compound represents a pioneering advancement in the development of effective antiviral agents against the SARS-CoV-2 virus.
价 格:¥电议型 号:T40358产 地:中国大陆
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T39869(Z)-2-Bromo-3-methyl-2-butenedioic acid;(Z)-2-溴-3-甲基-2-丁二酸cis-2-Bromo-3-methylbutenendioic acid;cis-
(Z)-2-Bromo-3-methyl-2-butenedioic acid is a brominated haloacid that acts as a disinfection byproduct (DBP) in finished drinking waters.
价 格:¥电议型 号:T39869产 地:中国大陆
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T38838QS-21;QS-21Stimulon|||QS-21;Stimulon|||QS-21
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.
价 格:¥电议型 号:T38838产 地:中国大陆
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T38542H-D-Phe-Pip-Arg-pNA acetateH-D-Phe-Pip-Arg-pNA acetateH-D-Phe-Pip-Arg-pNA acetate|||S-2238 acetate
H-D-Phe-Pip-Arg-pNA (S-2238) acetate is a chromogenic substrate designed based on the N-terminal fragment of the A alpha chain of fibrinogen, which is the physiological target of thrombin. As a specific indicator of thrombin activity, H-D-Phe-Pip-Arg-pNA acetate is utilized to quantify. This assay, utilizing H-D-Phe-Pip-Arg-pNA acetate, ensures high sensitivity, accuracy, and ease of execution.
价 格:¥电议型 号:T38542产 地:中国大陆