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T8845UTL-5gliver,inhibit,Inhibitor,chemoprotective,Tumor Necrosis Factor Receptor,radioprotective,acute,t
UTL-5g is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity. It lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice, and acts as a novel chemo- and radioprotective agent.
价 格：￥电议型 号：T8845产 地：中国大陆
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T7030anemarsaponin BNF-κB,Nuclear factor-kappaB,COX,MAP2K,anemarsaponin B,Mitogen-activated protein kinas
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.
价 格：￥电议型 号：T7030产 地：中国大陆
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T9304(S)-SunvozertinibHER1,Her2,(S)Sunvozertinib,mutant forms of ErbB,Epidermal growth factor receptor,(S
DZD9008 is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
价 格：￥电议型 号：T9304产 地：中国大陆
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T19786HematinInhibitor,Hematin,inhibit,fibrin clot,clotting factors,rat,hemostatic proteins,acute porphyri
Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.
价 格：￥电议型 号：T19786产 地：中国大陆
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TQ009920-O-Acetylingenol-3-angelateinhibit,Inhibitor,Euphorbia factor Pe-1,Euphorbia factor Pe 1,20OAcetyl
20-O-Acetylingenol-3-angelate is a natural compound from Euphorbia lathyris L.
价 格：￥电议型 号：TQ0099产 地：中国大陆
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TN1721Gypenoside LMAPK,Extracellular signal regulated kinases,NF-κB,Nuclear factor-κB,saponin,anti-tumor,N
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory activity.
价 格：￥电议型 号：TN1721产 地：中国大陆
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T9917DenosumabDenosumab,Immunoglobulin G2,Nuclear factor-kappaB,NF-κB,Immunoglobulin G-2,RANKL,Inhibitor,
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
价 格：￥电议型 号：T9917产 地：中国大陆
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T60037SR15006growth,inhibit,KLF5,SR 15006,Krüppel-like factor,SR15006,colorectal cancer cells,cycle,Inhibi
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
价 格：￥电议型 号：T60037产 地：中国大陆
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T7203OglufanideM21 human melanoma,anti-angiogenesis,Vascular endothelial growth factor receptor,HCV,inhib
Oglufanide is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
价 格：￥电议型 号：T7203产 地：中国大陆
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T8482Ripretinibc-Kit,Inhibitor,DCC2618,Vascular endothelial growth factor receptor,CD135,CD117,Platelet-d
Ripretinib is an orally bioavailable inhibitor of KIT and PDGFRA.
价 格：￥电议型 号：T8482产 地：中国大陆
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T6996SU 5402SU-5402,SU 5402,VEGFR,inhibit,Inhibitor,Fibroblast growth factor receptor,FGFR,Platelet-deriv
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
价 格：￥电议型 号：T6996产 地：中国大陆
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TN2008OkaninToll-like Receptor (TLR),Nuclear factor-κB,NF-κB,Inhibitor,Nuclear factor-kappaB,Okanin,inhibi
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.
价 格：￥电议型 号：TN2008产 地：中国大陆
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T6720Vatalanib dihydrochloridePTK-787,Inhibitor,Vascular endothelial growth factor receptor,VEGFR,PTK 787
Vatalanib (PTK787) (IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.
价 格：￥电议型 号：T6720产 地：中国大陆
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T6734WZ8040HER1,WZ 8040,mutated,WZ8040,Inhibitor,phosphorylation,EGFR,NSCLC,Epidermal growth factor recep
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).
价 格：￥电议型 号：T6734产 地：中国大陆
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TN2354MethylnissolinMethylnissolin,Astrapterocarpan,ERK,Inhibitor,Platelet-derived growth factor receptor,
3-Hydroxy-9,10-dimethoxyptercarpan is derived from Astragalus and has antibacterial and anti-cancer effects.
价 格：￥电议型 号：TN2354产 地：中国大陆
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T6S0071FraxinelloneHIFs,Hypoxia-inducible factors,Fraxinellone,HIF-PH,STAT,Inhibitor,inhibit,HIF/HIF Prolyl
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. 3. Fraxinellone has effect in the midgut metabolism of Mythimna separata (M. separata), via protease (especially the weak alkaline trypsin-like enzyme), carboxylesterase and glutathione S-transferase.
价 格：￥电议型 号：T6S0071产 地：中国大陆
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T7322TheliatinibATP-competitive,inhibit,EGFR,ERK,cancer,esophageal,Epidermal growth factor receptor,HMPL-
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
价 格：￥电议型 号：T7322产 地：中国大陆
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TL0001dencichineHypoxia-inducible factors,HIF/HIF Prolyl-Hydroxylase,dencichine,Inhibitor,HIFs,HIF-PH,inhi
Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effect, it could significantly prevent the progression of diabetic nephropathy possibly attribute to down-regulation of the TGF-β/Smad pathway and rebalance the deposition and degradation of ECM proteins.
价 格：￥电议型 号：TL0001产 地：中国大陆
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TN1525Convallatoxinpsoriasis,Nuclear factor-κB,P-gp,Inhibitor,anti-proliferative,colitic,anti-inflammatory
Convallatoxin is a natural product.
价 格：￥电议型 号：TN1525产 地：中国大陆
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TWA2417Sodium taurocholateI nterleukin-1β,Tumor necrosis factor-α,inhibit,Sodium taurocholate hydrate,Immun
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid.[3] These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
价 格：￥电议型 号：TWA2417产 地：中国大陆
