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T17872E3 ligase Ligand 14;化合物 T17872E3 ligase Ligand 14
E3 ligase Ligand 14 is a ligand that binds to E3 ubiquitin ligase and can be conjugated to a protein ligand via a linker to create PROTACs. These PROTACs are capable of promoting ubiquitination-mediated degradation of cancer-promoting proteins[1].
价 格:¥电议型 号:T17872产 地:中国大陆
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T17871E3 ligase Ligand 13;化合物 T17871E3 ligase Ligand 13
E3 ligase Ligand 13 is an E3 ubiquitin ligase ligand that can be employed to create PROTACs, which are connected to the ligand for the protein through a linker. PROTACs serve as inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
价 格:¥电议型 号:T17871产 地:中国大陆
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T17870cIAP1 ligand 1;cIAP1 配体1E3 ligase Ligand 12;E3 ligase Ligand 12
cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands for the development of protein degradation agents, which can be used in the study of prostate cancer.CAS ??13460-73-83-4
价 格:¥电议型 号:T17870产 地:中国大陆
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T17869cIAP1 ligand 2;化合物 T17869E3 ligase Ligand 11;E3 ligase Ligand 11
cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
价 格:¥电议型 号:T17869产 地:中国大陆
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T17868E3 ligase Ligand 10;化合物 T17868E3 ligase Ligand 10
E3 ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase and can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. These PROTACs act as inducers of ubiquitination-mediated degradation, specifically targeting cancer-promoting proteins[1].
价 格:¥电议型 号:T17868产 地:中国大陆
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T17819Thalidomide-O-amido-C8-NH2;化合物 T17819E3 Ligase Ligand-Linker Conjugates 20|||Cereblon Ligand-Linker
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of PROTACs, as per reference [1].
价 格:¥电议型 号:T17819产 地:中国大陆
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T17818Thalidomide-O-amido-C4-NH2;化合物 T17818E3 Ligase Ligand-Linker Conjugates 19|||Cereblon Ligand-Linker
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized ligand-linker conjugate that combines a Thalidomide-based cereblon ligand with a linker. It functions as an E3 ligase ligand-linker conjugate and finds applications in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17818产 地:中国大陆
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T17364AhR Ligand-Linker Conjugates 1;化合物 T17364E3 Ligase Ligand-Linker Conjugates 57;E3 Ligase Ligand-Link
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
价 格:¥电议型 号:T17364产 地:中国大陆
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T17325Pomalidomide-PEG4-C-COOH;化合物Pomalidomide-PEG4-C-COOHCereblon Ligand -Linker Conjugates 1|||E3 Ligase
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17325产 地:中国大陆
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T15190L(S,R,S)-AHPC-PEG4-NH2;化合物T15190LVHL Ligand-Linker Conjugates 4|||E3 ligase Ligand-Linker Conjugates
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker.
价 格:¥电议型 号:T15190L产 地:中国大陆
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T15190(S,R,S)-AHPC-PEG4-NH2 hydrochloride;化合物 T15190E3 ligase Ligand-Linker Conjugates 7|||VH032-PEG4-NH2
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
价 格:¥电议型 号:T15190产 地:中国大陆
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T15189Thalidomide-O-amido-C4-N3;化合物Thalidomide-O-amido-C4-N3E3 ligase Ligand-Linker Conjugates 18|||Cerebl
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
价 格:¥电议型 号:T15189产 地:中国大陆
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T13671L(S,R,S)-AHPC-Me dihydrochloride;化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demonstrates potent degradation of BET protein in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound serves as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, that facilitates the recruitment of von Hippel-Lindau (VHL) prote
价 格:¥电议型 号:T13671L产 地:中国大陆
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T13671(S,R,S)-AHPC-Me hydrochloride;化合物(S,R,S)-AHPC-Me hydrochlorideVHL ligand 2 hydrochloride|||E3 ligase
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.
价 格:¥电议型 号:T13671产 地:中国大陆