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T78488Palmaturbine hydroxide;化合物 Palmaturbine hydroxidePalmaturbine hydroxide
Palmatine hydroxide, isolated from T. sinensis [1], is a chemical compound.
价 格:¥电议型 号:T78488产 地:中国大陆
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T78483Benzydamine N-Oxide;化合物 Benzydamine N-OxideBenzydamine N-Oxide
Benzydamine N-Oxide, a metabolite of Benzydamine, serves as a biomarker for flavin-containing monooxygenase activity [1] [2].
价 格:¥电议型 号:T78483产 地:中国大陆
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T78346Superoxide dismutase;化合物 Superoxide dismutaseSOD;SOD
Superoxide dismutase (SOD), an exclusive antioxidant enzyme, catalyzes the dismutation of the superoxide anion into oxygen and hydrogen peroxide, averting peroxynitrite formation and subsequent harm. It is extensively studied and utilized in various applications, including anti-inflammatory, antitumor, radiation protection, and antisenility [1].
价 格:¥电议型 号:T78346产 地:中国大陆
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T77790Phenylarsine oxide;化合物 Phenylarsine oxideOxophenylarsine;Oxophenylarsine
Phenylarsine Oxide (Oxophenylarsine) is a membrane-permeable tyrosine phosphatase inhibitor with an IC50 value of 18 ?M that stimulates 2-deoxyglucose transport in insulin-resistant human skeletal muscle.
价 格:¥电议型 号:T77790产 地:中国大陆
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T75436Jatrorrhizine hydroxide;化合物 Jatrorrhizine hydroxideJatrorrhizine hydroxide
Jatrorrhizine hydroxide, an alkaloid derived from Coptis chinensis, exhibits a range of biological activities including neuroprotective, antimicrobial, antiplasmodial, and antioxidant properties [1]. It acts as a potent and orally active inhibitor of acetylcholinesterase (AChE) with an IC50 value of 872 nM, demonstrating over 115-fold greater selectivity for AChE compared to butyrylcholinesterase (BuChE) [2]. Additionally, Jatrorrhizine hydroxide impedes the uptake of serotonin (5-HT) and norepi
价 格:¥电议型 号:T75436产 地:中国大陆
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T7479Ambroxide;降龙涎香醚(-)-Ambroxide;降龙涎香醚|||(-)-Ambroxide
Ambroxide ((-)-Ambroxide) is a naturally product,is one of the key constituents of ambergris.
价 格:¥电议型 号:T7479产 地:中国大陆
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T74685Abiraterone N-oxide;化合物 Abiraterone N-oxideAbiraterone N-oxide
Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .
价 格:¥电议型 号:T74685产 地:中国大陆
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T74582Trimipramine N-oxide;化合物 Trimipramine N-oxideTrimipramine N-oxide
Trimipramine N-oxide, an active metabolite of the tricyclic antidepressant trimipramine, effectively inhibits human monoamine transporters for noradrenaline (hNAT), serotonin (hSERT), dopamine (hDAT), and the human organic cation transporters (hOCT1 and hOCT2), with IC50 values of 11.7, 3.59, 9.4, 9.35, and 27.4 nM, respectively. It is utilized in the research of depression and anxiety [1].
价 格:¥电议型 号:T74582产 地:中国大陆
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T74205Imipramine N-oxide;化合物 Imipramine N-oxideImipramine N-oxide
Imipramine N-oxide, a metabolite of Imipramine, is a tertiary amine tricyclic antidepressant [1] [2].
价 格:¥电议型 号:T74205产 地:中国大陆
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T74015Venetoclax N-oxide;化合物 Venetoclax N-oxideVenetoclax N-oxide
Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199), a highly potent, selective, and orally bioavailable inhibitor of Bcl-2, demonstrates a Ki value of less than 0.01 nM [1].
价 格:¥电议型 号:T74015产 地:中国大陆
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T73955Potassium clavulanate mixture with silicon dioxide (1:1);化合物 Potassium clavulanate mixture with sili
Potassium Clavulanate Mixture with Silicon Dioxide (1:1) is a compound consisting of an equal parts ratio, specifically one part Potassium Clavulanate to one part Silicon Dioxide, presented in a powdered form [1].
价 格:¥电议型 号:T73955产 地:中国大陆
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T73797Cladospirone bisepoxide;化合物 Cladospirone bisepoxideCladospirone bisepoxide
Cladospirone bisepoxide, a metabolite isolated from fungal cultures, exhibits selective antibiotic activity against various bacteria and fungi, and at low concentrations, it inhibits the germination of Lepidium sativum [1].
价 格:¥电议型 号:T73797产 地:中国大陆
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T73627Gefitinib N-oxide hydrochloride;化合物 Gefitinib N-oxide hydrochlorideGefitinib N-oxide hydrochloride
Gefitinib N-oxide hydrochloride, an N-oxide derivative of Gefitinib, acts as an EGFR tyrosine kinase inhibitor. Demonstrating an IC50 range of 2-37 nM in NR6wtEGFR cells, it emphasizes its efficacy in inhibiting the enzymatic activity of EGFR [1] [2].
价 格:¥电议型 号:T73627产 地:中国大陆
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T72508Palmatine hydroxide;化合物 Palmatine hydroxidePalmatine hydroxide
Palmatine hydroxide is an orally active, irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1), demonstrating IC50 values of 3 μM for HEK 293-hIDO-1 and 157μM for rhIDO-1. Additionally, it uncompetitively inhibits the West Nile virus (WNV) NS2B-NS3 protease with an IC50 of 96 μM. This compound exhibits a range of biological activities, including anti-cancer, anti-oxidation, anti-inflammatory, neuroprotective, antibacterial, and antiviral effects.
价 格:¥电议型 号:T72508产 地:中国大陆
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T72112Clozapine N-oxide dihydrochloride氯氮平N-氧化盐酸氯氮平N-氧化盐酸
Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier.Clozapine N-oxide dihydrochloride induces activation of DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride induces activation of DREADD receptors hM3Dq and hM4Di.
价 格:¥电议型 号:T72112产 地:中国大陆
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T71369Montelukast sulfoxide;化合物 Montelukast sulfoxideMontelukast sulfoxide
Montelukast sulfoxide is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
价 格:¥电议型 号:T71369产 地:中国大陆
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T71341Myclobutanil hydroxide;化合物 Myclobutanil hydroxideMyclobutanil hydroxide
Myclobutanil hydroxide is a 14-α demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. It also weakly inhibits testosterone production.
价 格:¥电议型 号:T71341产 地:中国大陆
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T71144Nilotinib N-oxide;化合物 Nilotinib N-oxideNilotinib N-oxide
Nilotinib N-oxide is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.
价 格:¥电议型 号:T71144产 地:中国大陆
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T70830Neratinib dimethylamine N-oxide;化合物 Neratinib dimethylamine N-oxideNeratinib dimethylamine N-oxide
Neratinib dimethylamine N-oxide is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity.
价 格:¥电议型 号:T70830产 地:中国大陆
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T70829Neratinib pyridine N-oxide;化合物 Neratinib pyridine N-oxideNeratinib pyridine N-oxide
Neratinib pyridine N-oxide is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity.
价 格:¥电议型 号:T70829产 地:中国大陆