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T14235Amino-PEG3-C2-sulfonic acid;化合物 T14235Amino-PEG3-C2-sulfonic acid
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker utilized for the synthesis of PROTACs [1].
价 格:¥电议型 号:T14235产 地:中国大陆
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T1422Nilvadipine;尼伐地平FK235|||FR34235|||ARC029;FK235|||FR34235|||尼伐地平|||ARC029
Nilvadipine (FK235), a calcium channel blocker (CCB), is utilized for treatment of hypertension.
价 格:¥电议型 号:T1422产 地:中国大陆
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T14219Aminaftone;化合物AminaftoneAminaphthone;Aminaphthone
Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.
价 格:¥电议型 号:T14219产 地:中国大陆
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T1421Aceclofenac;醋氯芬酸Preservex|||Airtal;醋氯芬酸|||Preservex|||Airtal
Aceclofenac (Preservex) is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties.
价 格:¥电议型 号:T1421产 地:中国大陆
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T14207Amcinafal;安西法尔SQ 15102;安西法尔|||SQ 15102
Amcinafal is an active diol,and used against virus replication and interferon production.
价 格:¥电议型 号:T14207产 地:中国大陆
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T14175Aldose reductase-IN-1;化合物Aldose reductase-IN-1AT-001|||Caficrestat;AT-001|||Caficrestat
Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).
价 格:¥电议型 号:T14175产 地:中国大陆
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T1415Gemfibrozil;吉非罗齐CI-719|||Jezil|||Decrelip|||Lopid;吉非罗齐|||CI-719|||Jezil|||Decrelip|||Lopid
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfibrozil is a fibric acid derivative with hypolipidemic effects. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III). The reduction in hepatic production of apoC-III result in the subsequent reduction of serum levels o
价 格:¥电议型 号:T1415产 地:中国大陆
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T1414Sodium 2-mercaptoethanesulfonate;美司钠Mitexan|||Uromitexan|||Mesna|||Mesnum|||Mesnex;Mitexan|||美司那|||美
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
价 格:¥电议型 号:T1414产 地:中国大陆
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T14134Afabicin;化合物 T14134AFN-1720|||Debio 1450;AFN-1720|||Debio 1450
Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
价 格:¥电议型 号:T14134产 地:中国大陆
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T14131ADPS;化合物ADPSN-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt|||ESPAS;N-Ethyl-N-(3-sulfopropyl)
ADPS (N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt) is a kind of new Trinder´s reagents, which are high water-soluble aniline derivatives. It is widely used in diagnostic and biochemical tests.
价 格:¥电议型 号:T14131产 地:中国大陆
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T14122Active-mono-sulfone-PEG8-acid;化合物 T14122Active-mono-sulfone-PEG8-acid
Active-mono-sulfone-PEG8-acid is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis[1].
价 格:¥电议型 号:T14122产 地:中国大陆
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T1411Terbinafine hydrochloride;盐酸特比萘芬KWD 2019|||Terbinafine HCl|||TDT 067 hydrochloride;KWD 2019|||盐酸特比萘芬
Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.
价 格:¥电议型 号:T1411产 地:中国大陆
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T14103Acid-PEG3-PFP ester;化合物 T14103Acid-PEG3-PFP ester
Acid-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14103产 地:中国大陆
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T14080AA147;化合物AA147ATF6-activator-147;ATF6-activator-147
AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.
价 格:¥电议型 号:T14080产 地:中国大陆
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T1406LAmantadine sulfate;化合物 T1406L1-Adamantanamine Sulfate;1-Adamantanamine Sulfate
Amantadine is used both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. The drug has many effects in the brain, including the release of dopamine and norepinephrine from nerve endings.
价 格:¥电议型 号:T1406L产 地:中国大陆
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T1405LCefditoren sodium化合物 T1405LCefditoren pivoxil|||Cefditoren|||ME-1206|||ME1206|||ME 1206
Cefditoren sodium is a cephalosporin antibiotic potentially for the treatment of bacterial infection. The expression levels of Mrp2, Bcrp, Oat2 mRNA were markedly increased, while P-gp and Oct1 mRNA were decreased. In concordance with RT-PCR results, Mrp2 expression level increased by Western blotting.
价 格:¥电议型 号:T1405L产 地:中国大陆
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T140596-Maleimidocaproic acid-PFP ester;化合物 T140596-Maleimidocaproic acid-PFP ester
6-Maleimidocaproic acid-PFP ester is a hydrocarbon-based PROTAC linker, suitable for the synthesis of PROTACs[1].
价 格:¥电议型 号:T14059产 地:中国大陆
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T140586-FITC6-异硫氰酸荧光素6-异硫氰酸荧光素|||6-Fluorescein Isothiocyanate
6-Fluorescein Isothiocyanate (6-FITC) is a fluorescein derivative widely employed in applications such as flow cytometry.
价 格:¥电议型 号:T14058产 地:中国大陆
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T140576-CFDA6-羧基荧光素二醋酸6-羧基荧光素二醋酸|||6-Carboxyfluorescein diacetate
6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.
价 格:¥电议型 号:T14057产 地:中国大陆
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T140555Z-7-Oxozeaenol;化合物5Z-7-OxozeaenolFR148083|||L783279|||LL-Z 1640-2;FR148083|||L783279|||LL-Z 1640-2
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
价 格:¥电议型 号:T14055产 地:中国大陆