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T70838RO27-3225 TFA；化合物 RO27-3225 TFARO27-3225 TFA
RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225 shows some activity at the MC1 receptor. Ro 27-3225 reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.
价 格：￥电议型 号：T70838产 地：中国大陆
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T70837Rimegepant sulfate hydrate；化合物 Rimegepant sulfate hydrateRimegepant sulfate hydrate
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown in vivo efficacy without vasoconstriction effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.
价 格：￥电议型 号：T70837产 地：中国大陆
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T70836DMJ-I-228；化合物 DMJ-I-228DMJ-I-228
DMJ-I-228 is a specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group.
价 格：￥电议型 号：T70836产 地：中国大陆
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T70835（4R，9S)-AG 205；化合物（4R，9S)-AG 205（4R，9S)-AG 205
AG-205 is a potent inhibitor of FabK, the enoyl-ACP reductase in Streptococcus pneumoniae.
价 格：￥电议型 号：T70835产 地：中国大陆
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T70834BE-16627B；化合物 BE-16627BBE-16627B
BE-16627B is a novel metalloproteinase (MP) inhibitor isolated from Streptomyces sp. BE16627B selectively inhibited MPs such as human stromelysin and 92 kD gelatinase. After the cells were cultured with BE16627B for 5 days, BE16627B inhibited MP activity in the primary culture supernatants from synovial cells in a dose-dependent fashion without showing apparent cytotoxicity or affecting the production and secretion of MPs. Its IC50 for active collagenolysis before activation by trypsin was 25 mi
价 格：￥电议型 号：T70834产 地：中国大陆
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T70833A-1293201；化合物 A-1293201A-1293201
A-1293201 is a potent and selective NAMPT inhibitor.
价 格：￥电议型 号：T70833产 地：中国大陆
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T70832Bisindolylmaleimide VII；化合物 Bisindolylmaleimide VIIBisindolylmaleimide VII
Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.
价 格：￥电议型 号：T70832产 地：中国大陆
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T70831Glutathione maleimide；化合物 Glutathione maleimideGlutathione maleimide
Glutathione maleimide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
价 格：￥电议型 号：T70831产 地：中国大陆
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T70830Neratinib dimethylamine N-oxide；化合物 Neratinib dimethylamine N-oxideNeratinib dimethylamine N-oxide
Neratinib dimethylamine N-oxide is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity.
价 格：￥电议型 号：T70830产 地：中国大陆
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T7083GLPG1837；化合物GLPG1837ABBV-974；ABBV-974
GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
价 格：￥电议型 号：T7083产 地：中国大陆
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T70083Cilengitide hydrochloride；化合物 Cilengitide hydrochlorideCilengitide hydrochloride
Cilengitide hydrochloride sis the salt form of Cilengitide, a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
价 格：￥电议型 号：T70083产 地：中国大陆
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T69461Ro 20-0083；化合物 Ro 20-0083Ro 20-0083
Ro 20-0083 is an inhibitor of hepatic fatty acid synthesis.
价 格：￥电议型 号：T69461产 地：中国大陆
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T69083Nitraquazone；化合物 NitraquazoneNitraquazone
Nitraquazone is a phosphodiesterase inhibitor
价 格：￥电议型 号：T69083产 地：中国大陆
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T68986ZINC08383544；化合物 ZINC08383544ZINC08383544
ZINC08383544 is a specific pyruvate kinase M2 activator which promotes the formation of PKM2 tetramer. ZINC08383544 effectively blocks PKM2 nuclear translocation, and inhibits the growth of tumor.
价 格：￥电议型 号：T68986产 地：中国大陆
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T68538CEP-14083；化合物 CEP-14083CEP-14083
CEP-14083 is a potent ALK inhibitor that has shown activity in an NPM/ALK?–carrying T-cell lymphoma in vitro study. Presumably, this compound binds to the hinge region of the kinase in an ATP-competitive manner. CEP-14083 displays a potent activity against ALK in enzymatic assays (IC50 = 11 nmol/L). Further, CEP-14083 is also able to inhibit the insulin receptor at a concentration within a nanomolar range. In a preclinical assay, CEP-14083 showed that, via NPM/ALK TK inhibition, it could control
价 格：￥电议型 号：T68538产 地：中国大陆
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T68249IRC-083927 HCl；化合物 IRC-083927 HClIRC-083927 HCl
IRC-083927 HCl is novel and potent microtubule inhibitor with potential anticancer activity. IRC-083927 inhibits the tubulin polymerization by a binding to the colchicine site. IRC-083927 inhibits in vitro cell growth of human cancer cell lines in the low nanomolar range. More interesting, it remains highly active against cell lines resistant to microtubule-interacting agents (taxanes, Vinca alkaloids, or epothilones). Chronic oral treatment with IRC-083927 (5 mg/kg) inhibits the growth of two h
价 格：￥电议型 号：T68249产 地：中国大陆
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T68246IRC-083927 free base；化合物 IRC-083927 free baseIRC-083927 free base
IRC-083927 free base is novel and potent microtubule inhibitor with potential anticancer activity.
价 格：￥电议型 号：T68246产 地：中国大陆
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T68083Ldl-Ibuterol hydrochloride；dl-Ibuterol 盐酸盐dl-Ibuterol hydrochloride (53034-85-8 Free base)|||dl-Ibute
dl-Ibuterol hydrochloride (Ibuterol HCl) has vasodilatory activity and can be used to study asthma and bronchospasm.
价 格：￥电议型 号：T68083L产 地：中国大陆
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T6796CB-5083；化合物CB5083CB5083|||CB 5083；CB5083|||CB 5083
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
价 格：￥电议型 号：T6796产 地：中国大陆
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T67083H-D-Chg-OH；化合物 H-D-Chg-OHH-D-Chg-OH
H-D-Chg-OH is an amino acid derivative and has a wide range of applications in life science related research.
价 格：￥电议型 号：T67083产 地：中国大陆
