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产品数:86101
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T7947FT113FT 113,Fatty Acid Synthase (FASN),Inhibitor,FT-113,FT113,inhibit
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
价 格:¥电议型 号:T7947产 地:中国大陆
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TN11428-Oxocoptisine8-Oxocoptisine,inhibit,Inhibitor,8 Oxocoptisine,8Oxocoptisine
8-Oxycoptisine is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer
价 格:¥电议型 号:TN1142产 地:中国大陆
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T70421,5-IsoquinolinediolPARP,diabetic,1188540,oxidative,retinopathy,1,5 Isoquinolinediol,stress,inhibit,
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
价 格:¥电议型 号:T7042产 地:中国大陆
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TN5118Taxol CTaxol C
Taxol C can reduce interaction with the P-glycoprotein transporter that may allow for increased permeation of taxanes into the brain.
价 格:¥电议型 号:TN5118产 地:中国大陆
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TP1200CGRP (83-119), rat TFACGRP (83 119), rat TFA,CGRP (83119), rat TFA
Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
价 格:¥电议型 号:TP1200产 地:中国大陆
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T7612ICA 110381inhibit,ICA 110381,Potassium Channel,ICA-110381,KcsA,ICA110381,Inhibitor
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
价 格:¥电议型 号:T7612产 地:中国大陆
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TP1991LM 1145 acetateM 1145 acetate
M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 acetate has an additive effect on the signal transduction of galanin[1].
价 格:¥电议型 号:TP1991L产 地:中国大陆
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T8230PNU112455A hydrochlorideanticooperative,Cyclin dependent kinase,PNU112455A hydrochloride,Alzheimer’s
PNU 112455A is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
价 格:¥电议型 号:T8230产 地:中国大陆
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T20490NSC-120011
NSC-120011 can be used in the assay to screen proteolytic activities in mite homogenates.
价 格:¥电议型 号:T20490产 地:中国大陆
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T9011VU0155094VU0155094,Inhibitor,Metabotropic glutamate receptors,ML397,inhibit,mGluR
ML397 is a positive allosteric modulator with differential activity at the various group III mGluRs.
价 格:¥电议型 号:T9011产 地:中国大陆
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T17117Tonapofylline
Tonapofylline is an orally active and selective antagonist of the A1 adenosine receptor (Ki: 7.4 nM for human A1). Tonapofylline can be used in studies about heart failure.
价 格:¥电议型 号:T17117产 地:中国大陆
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T6501Fludarabine PhosphateNSC 118218,Fludarabine Phosphate,Inhibitor,Fludarabine,inhibit,NSC118218,Nucleo
Fludarabine Phosphate is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase, and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell gr
价 格:¥电议型 号:T6501产 地:中国大陆
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T6479Dovitinib lactate hydrateVEGFR1,FGFR1,TKI258 lactate,SCFR,CD117,Dovitinib lactate hydrate,FGFR,Fms l
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
价 格:¥电议型 号:T6479产 地:中国大陆
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T8884hSMG-1 inhibitor 11jhSMG 1 inhibitor 11j,hSMG1 inhibitor 11j
hSMG-1 inhibitor 11j is a pyrimidine derivative. hSMG-1 inhibitor 11j is a potent and selective inhibitor of hSMG-1, IC50 = 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer.
价 格:¥电议型 号:T8884产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆
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T7115PymetrozinePymetrozine,Bacterial,CGA-215944,inhibit,CGA215944,Inhibitor
Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae.
价 格:¥电议型 号:T7115产 地:中国大陆
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TN1110Shanzisideinhibit,Inhibitor,Iridoid,Shanziside,glucoside
Shanzhiside has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.
价 格:¥电议型 号:TN1110产 地:中国大陆
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TP1195Cibinetideinhibit,ARA 290,Cibinetide,Inhibitor,ARA-290
ARA290 is a nonerythropoietic peptide engineered from erythropoietin,, and used for neurological disease treatment.
价 格:¥电议型 号:TP1195产 地:中国大陆
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T7424NDI-091143NDI 091143,ACLY,inhibit,ATP Citrate Lyase,NDI-091143,NDI091143,Inhibitor
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
价 格:¥电议型 号:T7424产 地:中国大陆
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T11784KT182KT182,KT-182
KT182 is a selective and ?potent inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.
价 格:¥电议型 号:T11784产 地:中国大陆