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  • T2248AS-605240AS-605240,AS605240,AS 605240

    AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).

    价 格：￥电议型 号：T2248产 地：美洲

  • T2249XEN-445XEN-445,XEN445,XEN 445

    XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.

    价 格：￥电议型 号：T2249产 地：美洲

  • T2488BAY 87-2243BAY 87-2243

    BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).

    价 格：￥电议型 号：T2488产 地：美洲

  • T52242-Hydroxycaproic acid2-Hydroxycaproic acid

    2-Hydroxycaproic acid is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hydroxycaproic acid is the most significant metabolite found in the CSF of patients infected with

    价 格：￥电议型 号：T5224产 地：美洲

  • T5416T-5224T-5224

    T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors.

    价 格：￥电议型 号：T5416产 地：美洲

  • T6224IniparibIniparib,IND-71677,NSC-746045

    Iniparib (BSI-201) ，a PARP1 inhibitor， exhibits potency in triple-negative breast Y (TNBC).

    价 格：￥电议型 号：T6224产 地：美洲

  • T8847Fosravuconazole L-lysine ethanolate；化合物T8847BMS-379224 L-lysine ethanolate|||E-1224 L-lysine ethanol

    Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate) is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.

    价 格：￥电议型 号：T8847产 地：中国大陆

  • T83895NCI 126224；化合物 NCI 126224NSC 126224；NSC 126224

    NCI 126224, a toll-like receptor 4 (TLR4) antagonist, demonstrates selective inhibition of nitric oxide (NO) production in RAW 264.7 macrophages, triggered by the TLR4 agonist LPS (IC50 = 0.31 ?M), as opposed to minimal effects on NO production induced by agonists for TLR7/8 (R-848), TLR1/2 (Pam3CSK4), and TLR3 (poly(I:C)). Nevertheless, it also effectively inhibits NO production initiated by the TLR2/6 agonist FSL-1 at an IC50 of 0.6 ?M in the same cell line. Moreover, NCI 126224 suppresses LPS

    价 格：￥电议型 号：T83895产 地：中国大陆

  • T837674-Hydroxyphenylglyoxylic Acid；化合物 4-Hydroxyphenylglyoxylic AcidUK 22486；UK 22486

    4-Hydroxyphenylglyoxylic acid, an active metabolite of the prodrug oxfenicine, functions as an inhibitor of carnitine palmitoyltransferase 1 (CPT1). It effectively inhibits CPT1 in isolated rat liver mitochondria at concentrations of 200 to 1,000 ?M and restricts oleate oxidation in isolated rat hepatocytes.

    价 格：￥电议型 号：T83767产 地：中国大陆

  • T83224AADvac 1；化合物 AADvac 1AADvac 1

    AADvac1 is a biologically active peptide functioning as an Alzheimer´s Disease Peptide Vaccine, composed of Tau(294–305) conjugated to Keyhole Limpet Hemocyanin (KLH).

    价 格：￥电议型 号：T83224产 地：中国大陆

  • T82249Gymnemanol；化合物 GymnemanolGymnemanol

    Gymnemanol, a triterpene, is isolated from the plant Gymnema sylvestre (Gymnema sylvestre).

    价 格：￥电议型 号：T82249产 地：中国大陆

  • T82248Gymnoside I；化合物 Gymnoside IGymnoside I

    Gymnoside I (compound 1), a glycosidoxybenzyl 2-isobutylmalic acid, exhibits antiallergic properties, particularly in the passive cutaneous allergic reaction (PCA) test in mice. It holds potential for research applications in the treatment of asthma, neurasthenia, and chronic hepatitis [1].

    价 格：￥电议型 号：T82248产 地：中国大陆

  • T82247Gymnoside IX；化合物 Gymnoside IXGymnoside IX

    Gymnoside IX (compound 2), isolated from the methanolic extract of Gymnadenia conopsea tubers [1], is a chemical entity that exhibits unique properties.

    价 格：￥电议型 号：T82247产 地：中国大陆

  • T82246H7；化合物 H7H7

    H7 is a second near-infrared (NIR-II) fluorophore [1].

    价 格：￥电议型 号：T82246产 地：中国大陆

  • T82245HA-CD44 interaction inhibitor 1；化合物 HA-CD44 interaction inhibitor 1HA-CD44 interaction inhibitor 1

    Antitumor agent-109 (compound 6) is a dual-function inhibitor that targets hyaluronic acid and CD44, which are involved in tumor progression and invasion. It demonstrates potent antitumor activity, specifically inhibiting MDA-MB-231 cells with an EC50 of 0.59 ?M [1].

    价 格：￥电议型 号：T82245产 地：中国大陆

  • T82244HA-CD44 interaction inhibitor 2；化合物 HA-CD44 interaction inhibitor 2HA-CD44 interaction inhibitor 2

    Antitumor Agent-108 (Compound 5), an inhibitor of the Hyaluronic Acid (HA)-CD44 interaction, effectively disrupts cancer spheroid integrity and exhibits antiproliferative activity against cancer cells [1].

    价 格：￥电议型 号：T82244产 地：中国大陆

  • T82243hAChE-IN-5；化合物 hAChE-IN-5hAChE-IN-5

    hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with IC50 values of 0.17 μM for both enzymes. Additionally, it demonstrates potent glycogen synthase kinase 3 beta (GSK3β) inhibition with an IC50 of 0.21 μM. The compound is an effective inhibitor of tau protein and Aβ1-42 peptide self-aggregation. It can virtually bind the peripheral anionic site (PAS), preventing amyloid-beta (Aβ)-induced n

    价 格：￥电议型 号：T82243产 地：中国大陆

  • T82242hAChE-IN-6；化合物 hAChE-IN-6hAChE-IN-6

    hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM. It also demonstrates inhibitory effects on human butyrylcholinesterase (hBuChE) and glycogen synthase kinase 3 beta (GSK3β), with IC50 values of 0.69 μM and 0.26 μM, respectively. Additionally, hAChE-IN-6 impedes the self-aggregation of tau protein and amyloid-beta 1-42 (Aβ1-42), rendering it useful for Alzheimer´s disease (AD) research [1].

    价 格：￥电议型 号：T82242产 地：中国大陆

  • T82241Halichondrin B；化合物 Halichondrin BHalichondrin B

    Halichondrin B, sourced from the sponge Halichondria okadai, serves as a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin, with an IC 50 for tubulin polymerization ranging from 1.2-1.4 μM, and exhibits anti-tumor activity [1].

    价 格：￥电议型 号：T82241产 地：中国大陆

  • T82240Haloxyfop-P-methyl；化合物 Haloxyfop-P-methylHaloxyfop-P-methyl

    Haloxyfop-P-methyl, an aryloxyphenoxypropionate herbicide, is absorbed through both foliage and roots, where it inhibits lipogenesis and induces oxidative stress in susceptible plant species [1].

    价 格：￥电议型 号：T82240产 地：中国大陆

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