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T62458EGFR-IN-56;化合物 EGFR-IN-56EGFR-IN-56
EGFR-IN-56 (Compound 13a) is a potent inhibitor of EGFR, acting on EGFRT790M (IC50: 541.7 nM) and EGFRT790M/L858R (IC50: 132.1 nM). EGFR-IN-56 blocks the cell cycle of cancer cells in the G2/M phase and induces EGFR-IN-56 blocks the G2/M phase of the cancer cell cycle and induces apoptosis.
价 格:¥电议型 号:T62458产 地:中国大陆
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T61458HIF-PHD-IN-2;化合物 HIF-PHD-IN-2HIF-PHD-IN-2
HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].
价 格:¥电议型 号:T61458产 地:中国大陆
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T61122ZINC12409120;化合物ZINC12409120R-4584;R-4584
ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23:α-Klotho interaction.
价 格:¥电议型 号:T61122产 地:中国大陆
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T60458NS2B/NS3-IN-4;化合物 NS2B/NS3-IN-4NS2B/NS3-IN-4
Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 ?M for DENV2 and 1.04 ?M for ZIKV NS2B/NS3 proteases [1].
价 格:¥电议型 号:T60458产 地:中国大陆
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T5458Darusentan;达卢生坦Lu-135252;Lu-135252|||达卢生坦
Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteries
价 格:¥电议型 号:T5458产 地:中国大陆
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T4A2458Resibufogenin;酯蟾毒配基Bufogenin|||Recibufogenin;酯蟾毒配基|||Bufogenin|||Recibufogenin|||酯蟾毒配基,蟾力苏
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina´s major metabolic path
价 格:¥电议型 号:T4A2458产 地:中国大陆
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T4588Glycochenodeoxycholic Acid;甘氨鹅脱氧胆酸Glycine chenodeoxycholate|||Chenodeoxycholylglycine|||GCDCA|||Glyc
Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
价 格:¥电议型 号:T4588产 地:中国大陆
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T4587Mirificin;芹糖葛根素苷BCP10902|||Puerarin Apioside;BCP10902|||Puerarin Apioside|||葛根素芹菜糖苷|||芹糖葛根素苷
Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.
价 格:¥电议型 号:T4587产 地:中国大陆
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T4586(Rac)-Arnebin 1;β,β-二甲基丙烯酰阿卡宁beta, beta-dimethylacrylshikonin;β,β-二甲基丙烯酰阿卡宁|||beta, beta-dimethylacr
(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.
价 格:¥电议型 号:T4586产 地:中国大陆
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T4585EGTA;乙二醇双(2-氨基乙基醚)四乙酸Ethylenebis(oxyethylenenitrilo)tetraacet;Ethylenebis(oxyethylenenitrilo)tetraac
Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
价 格:¥电议型 号:T4585产 地:中国大陆
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T4584BMS-813160;化合物BMS813160BMS 813160;BMS 813160
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
价 格:¥电议型 号:T4584产 地:中国大陆
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T4583PFI-2 hydrochloride;化合物(R)-PFI-2 hydrochloride(R)-PFI-2 hydrochloride|||PFI-2 HCl;(R)-PFI-2 hydrochl
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.
价 格:¥电议型 号:T4583产 地:中国大陆
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T4582xanthanol;占吨氢醇NSC 4038;NSC 4038|||占吨氢醇
Xanthanol(NSC 4038) is used to test the levels of urea in the bloodstream.
价 格:¥电议型 号:T4582产 地:中国大陆
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T45804-Octyl itaconate4-辛基衣康酸4-辛基衣康酸|||衣康酸盐
4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite. 4-Octyl Itaconate activates Nrf2 via alkylation of KEAP1 and also inhibits phosphorylation of STING. 4-Octyl Itaconate is an anti-inflammatory metabolite.
价 格:¥电议型 号:T4580产 地:中国大陆
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T41165ETP 45835 dihydrochloride;ETP 45835 dihydrochlorideETP 45835 dihydrochloride
ETP 45835 dihydrochloride is a Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein Ki nases, including those upstream of Mnk1/2.
价 格:¥电议型 号:T41165产 地:中国大陆
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T404583-Keto petromyzonol;3-Keto petromyzonol3-Keto petromyzonol
3-Keto petromyzonol, a key constituent of Sea lamprey male sex pheromones, governs the synthesis and release of gonadotropin releasing hormone (GnRH). This in turn regulates the hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey.
价 格:¥电议型 号:T40458产 地:中国大陆
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T39458DGN549-C;DGN549-CDGN549-C;DGN549-C
DGN549-C is a novel compound featuring a cleavable ADC (antibody-drug conjugate) linker composed of valine-alanine (va) and a PBD (pyrrolobenzodiazepine) dimer. This compound possesses a unique DNA-alkylating cytotoxic payload, DGN549, which is utilized in the development of ADCs.
价 格:¥电议型 号:T39458产 地:中国大陆
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T38458Faropenem;FaropenemFaropenem
Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory
价 格:¥电议型 号:T38458产 地:中国大陆
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T37458C18 Phytoceramide (t18:0/18:0);C18 Phytoceramide (t18:0/18:0)C18 Phytoceramide (t18:0/18:0)
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TN
价 格:¥电议型 号:T37458产 地:中国大陆