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T61549HDAC8-IN-2;化合物 HDAC8-IN-2HDAC8-IN-2
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and greatly reduces egg laying in adult worm pairs [1].
价 格:¥电议型 号:T61549产 地:中国大陆
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T5549Melamine三聚氰胺Cyanurotriamide|||Cyanuramide|||三聚氰胺
Melamine (Cyanurotriamide) is a widely-used intermediate, mainly employed as a raw material for producing melamine resin. It is also a metabolite of cyromazine formed in the body of mammals who have ingested cyromazine.
价 格:¥电议型 号:T5549产 地:中国大陆
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T5499gardiquimod TFA salt;化合物 T5499gardiquimod TFA salt
Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM. Gardiquimod diTFA could function as both an immune system modifier and a reverse transcriptase inhibitor as a novel therapeutic agent to block systemic and mucosal transmission of HIV-1.[1] [2].
价 格:¥电议型 号:T5499产 地:中国大陆
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T5498SB-649868;化合物SB-649868GSK649868;GSK649868
SB-649868 (GSK649868) is a potent and selective orally active antagonist of orexin(pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).
价 格:¥电议型 号:T5498产 地:中国大陆
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T5497AMAROGENTIN苦龙胆酯苷苦杏苷|||苦龙胆酯苷
Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis
价 格:¥电议型 号:T5497产 地:中国大陆
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T5496ML-030;化合物ML-030ML-030
ML-030 is a potent and selective inhibitor of PDE4(PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2 with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM, respectively)
价 格:¥电议型 号:T5496产 地:中国大陆
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T5495Decloxizine dihydrochloride;盐酸去氯羟嗪UCB 1402 dihydrochloride;盐酸去氯羟嗪|||UCB 1402 dihydrochloride
Decloxizine dihydrochloride (UCB 1402 dihydrochloride) is a histamine 1 receptor antagonist.
价 格:¥电议型 号:T5495产 地:中国大陆
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T5494MW-150;化合物MW-150MW01-18-150SRM;MW01-18-150SRM
MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.
价 格:¥电议型 号:T5494产 地:中国大陆
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T5493Pyronaridine;咯萘啶Pyronaridine
Pyronaridine is an orally active, mannitol-containing anti-malarial compound that acts by interfering with the replication of the malaria parasite (Plasmodium) within red blood cells. Pyronaridine is often used in combination with other drugs to treat malaria and has infective activity against P. falciparum and Echinococcus granulosus.
价 格:¥电议型 号:T5493产 地:中国大陆
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T5492JAK3-IN-6;化合物JAK3-IN-6JAK3-IN-6
JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM
价 格:¥电议型 号:T5492产 地:中国大陆
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T5491GSK3179106;化合物GSK3179106GSK3179106
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM
价 格:¥电议型 号:T5491产 地:中国大陆
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T5490AK-7;化合物AK-7AK-7
AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.
价 格:¥电议型 号:T5490产 地:中国大陆
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T5432Eganelisib;化合物IPI-549IPI-549;IPI-549
Eganelisib (IPI-549) is an inhibitor of PI3Kγ (IC50 = 16, 3,200, 3,500, and >8,400 nM for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively)
价 格:¥电议型 号:T5432产 地:中国大陆
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T4136Lapachol;黄钟花醌Bethabarra wood|||CI75490|||Greenhartin|||Tecomin;Bethabarra wood|||CI75490|||黄钟花醌|||Gr
Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
价 格:¥电议型 号:T4136产 地:中国大陆
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T41149BOP-JF549;BOP-JF549BOP-JF549;BOP-JF549
BOP-JF549 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor? 549. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 549 nm; emission maximum = 571 nm.
价 格:¥电议型 号:T41149产 地:中国大陆
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T40549PPA;PPAPPA
PPA serves as an ADC linker (US20060073528A1), facilitating the production of antibody-drug conjugates.
价 格:¥电议型 号:T40549产 地:中国大陆
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T39759Janelia Fluor? 549 TFA;Janelia Fluor? 549 TFAJF549 TFA;JF549 TFA
Janelia Fluor 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm.
价 格:¥电议型 号:T39759产 地:中国大陆
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T39458DGN549-C;DGN549-CDGN549-C;DGN549-C
DGN549-C is a novel compound featuring a cleavable ADC (antibody-drug conjugate) linker composed of valine-alanine (va) and a PBD (pyrrolobenzodiazepine) dimer. This compound possesses a unique DNA-alkylating cytotoxic payload, DGN549, which is utilized in the development of ADCs.
价 格:¥电议型 号:T39458产 地:中国大陆
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T39316DGN549-L;DGN549-LDGN549-L;DGN549-L
DGN549-L is a DNA alkylator that facilitates antibody conjugation at lysine residues, making it suitable for antibody-drug conjugate (ADC) synthesis.
价 格:¥电议型 号:T39316产 地:中国大陆
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T39241PA Janelia Fluor? 549, SE;PA Janelia Fluor? 549, SEPA Janelia Fluor? 549, SE|||PA-JF549-NHS;PA Janel
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549, SE (JF549, NHS). JF549, SE (JF549, NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm.
价 格:¥电议型 号:T39241产 地:中国大陆