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  • T39240Janelia Fluor? 549, SE；Janelia Fluor? 549, SEJF549, SE|||JF549,NHS；JF549, SE|||JF549,NHS

    Janelia Fluor 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm.

    价 格：￥电议型 号：T39240产 地：中国大陆

  • T38549Azido-C1-PEG3-C3-NH2；Azido-C1-PEG3-C3-NH2Azido-C1-PEG3-C3-NH2；Azido-C1-PEG3-C3-NH2

    Azido-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T38549产 地：中国大陆

  • T37549Bacillosporin CBacillosporin CBacillosporin C

    Bacillosporin C is an oxaphenalenone dimer originally isolated from T. bacillosporus. Bacillosporin C, an anhydride, is formed from the lactone bacillosporin D in the mangrove endophytic fungus SBE-14. Similar oxaphenalenone dimers have antibiotic activity and inhibit acetylcholinesterase.

    价 格：￥电议型 号：T37549产 地：中国大陆

  • T37113Z62954982；化合物 Z62954982ZINC08010136；ZINC08010136

    Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arterioles.

    价 格：￥电议型 号：T37113产 地：中国大陆

  • T36549CAY10486；CAY10486CAY10486

    Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.

    价 格：￥电议型 号：T36549产 地：中国大陆

  • T35549Elsinochrome A；Elsinochrome AElsinochrome A

    Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus monkey embryonic stem cells and HCe-8693 colorectal carcinoma cells when used at concentrations ranging from 1 to 100 μM.

    价 格：￥电议型 号：T35549产 地：中国大陆

  • T35499β-Amyloid (1-42), (rat/mouse) (TFA)；β-Amyloid (1-42)(大鼠/小鼠) (三氟乙酸盐)Amyloid β-peptide (1-42) (human)

    β-Amyloid (1-42), (rat/mouse) (TFA) is a peptide fragment consisting of 42 amino acids that can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T35499产 地：中国大陆

  • T35498β-Amyloid (1-14),mouse,rat；β-Amyloid (1-14),mouse,ratβ-Amyloid (1-14),mouse,rat

    β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide.

    价 格：￥电议型 号：T35498产 地：中国大陆

  • T35497(±)7(8)-EpDPA；(±)7(8)-EpDPA(±)7(8)-EpDPA

    Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting

    价 格：￥电议型 号：T35497产 地：中国大陆

  • T35496(±)13(14)-EpDPA；(±)13(14)-EpDPA(±)13(14)-EpDPA

    Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy m

    价 格：￥电议型 号：T35496产 地：中国大陆

  • T35495(±)13(14)-DiHDPA；(±)13(14)-DiHDPA(±)13(14)-DiHDPA

    (±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. Epoxygenase metabolites of DHA, including (±)13(14)-DiHDPA, are reported to inhibit angiogenesis, tumor growth, and metastasis.

    价 格：￥电议型 号：T35495产 地：中国大陆

  • T35494(±)11(12)-EET；(±)11(12)-EET(±)11(12)-EET

    (±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms CYP2C23 and CYP2C24 while CYP2B2 produces a higher proportion of 11(S),12(R)-EET.[3]11(12)-EET has been shown, along with 8(9)-EET to play a role in the recovery of depleted calcium pools in cultured smooth muscle cells[4] It also inhibits basolateral 18-pS potassium channels in t

    价 格：￥电议型 号：T35494产 地：中国大陆

  • T35493(±)10(11)-EpDPA；(±)10(11)-EpDPA(±)10(11)-EpDPA

    Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in infla

    价 格：￥电议型 号：T35493产 地：中国大陆

  • T35492(±)10(11)-DiHDPA；(±)10(11)-DiHDPA(±)10(11)-DiHDPA

    (±)10(11)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid . It has been shown to inhibit VEGF-induced angiogenesis in mice and may have additional anti-inflammatory and anti-tumor effects.

    价 格：￥电议型 号：T35492产 地：中国大陆

  • T354913,5-dimethyl PIT-13,5-dimethyl PIT-13,5 dimethyl PIT 1|||3,5dimethyl PIT1

    PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking and initiates an intricate signaling cascade that has been implicated in cancer. 3,5-dimethyl PIT-1 is a dimethyl analog of PIT-1, the selective inhibitor of PIP3/Akt PH domain binding, that is designed for more favorab

    价 格：￥电议型 号：T35491产 地：中国大陆

  • T354902-Amino-5-bromo-6-chloropyrazine；2-Amino-5-bromo-6-chloropyrazine2-Amino-5-bromo-6-chloropyrazine

    2-Amino-5-bromo-6-chloropyrazine is a heterocyclic building block.1,2It has been used in the synthesis of Akt inhibitors.

    价 格：￥电议型 号：T35490产 地：中国大陆

  • T3549Avadomide；化合物AvadomideCC 122；CC 122

    Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.

    价 格：￥电议型 号：T3549产 地：中国大陆

  • T34989UK 35493；化合物 T34989UK35493|||UK-35493；UK35493|||UK-35493

    UK is a bioactive chemical.

    价 格：￥电议型 号：T34989产 地：中国大陆

  • T34983UCM 549；化合物 T34983UCM549|||UCM-549；UCM549|||UCM-549

    UCM 549 is a bioactive chemical.

    价 格：￥电议型 号：T34983产 地：中国大陆

  • T34549SC 29169；化合物 T34549SC29169|||SC-29169；SC29169|||SC-29169

    SC 29169 is a prostaglandin analog.

    价 格：￥电议型 号：T34549产 地：中国大陆

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