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T75774Kisspeptin-54(human) TFA;化合物 Kisspeptin-54(human) TFAKisspeptin-54(human) TFA
Kisspeptin-54(human) TFA, also known as Metastin(human) TFA, is the natural ligand for the kisspeptin receptor (KISS1, GPR54). It demonstrates high affinity for both rat and human GPR54 receptors with dissociation constants (K i) of 1.81 nM and 1.45 nM, respectively. This compound plays a crucial role in inhibiting tumor metastasis and promoting the secretion of gonadotropins, as evidenced by references [1] [2].
价 格:¥电议型 号:T75774产 地:中国大陆
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T74774Neuraminidase-IN-16;化合物 Neuraminidase-IN-16Neuraminidase-IN-16
Neuraminidase-IN-16 (Compound 43b) serves as a potent inhibitor of neuraminidase, demonstrating IC50 values of 0.031, 0.15, 0.25, 0.60, 0.63, and 10.08 μM against the neuraminidase from H5N1, H5N8, H1N1, H3N2, H5N1–H274Y, and H1N1–H274Y strains, respectively [1].
价 格:¥电议型 号:T74774产 地:中国大陆
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T73774(S)-3,4-Dihydroxybutyric acid lithium hydrate;化合物 (S)-3,4-Dihydroxybutyric acid lithium hydrate(S)-3
(S)-3,4-Dihydroxybutyric acid (lithium hydrate) represents a common metabolite found in human urine, with elevated levels observed in individuals suffering from succinic semialdehyde dehydrogenase (SSADH) deficiency [1].
价 格:¥电议型 号:T73774产 地:中国大陆
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T7300GDC-0575;化合物GDC-0575ARRY-575|||RG7741;ARRY-575|||RG7741
GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).
价 格:¥电议型 号:T7300产 地:中国大陆
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T72774Ras modulator-1;化合物 Ras modulator-1Ras modulator-1
Ras modulator-1 is a modulator of Ras.
价 格:¥电议型 号:T72774产 地:中国大陆
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T71774Territrem B;化合物 Territrem BTerritrem B
Territrem B is a mycotoxin that irreversibly inhibits acetylcholinesterase (AChE). It is toxic to mice, inducing tremors with a median tremulous dose of 0.21 mg/kg.
价 格:¥电议型 号:T71774产 地:中国大陆
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T71434L 657743;化合物 L 657743L 657743
L 657743 is an Adrenergic alpha-Antagonist.
价 格:¥电议型 号:T71434产 地:中国大陆
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T71335PF-3774076;化合物 PF-3774076PF-3774076
PF-3774076 is a CNS penetrant, potent, selective, partial agonist at the human α1A adrenoceptor. PF-3774076 is selective over α1B and α1D adrenoceptors.
价 格:¥电议型 号:T71335产 地:中国大陆
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T70774Clavicoronic acid;化合物 Clavicoronic acidClavicoronic acid
Clavicoronic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.
价 格:¥电议型 号:T70774产 地:中国大陆
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T70435BMS-187745;化合物 BMS-187745BMS-187745
BMS-187745 is a squalene synthase inhibitor.
价 格:¥电议型 号:T70435产 地:中国大陆
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T69774VUF14738;化合物 VUF14738VUF14738
VUF14738 is a robust and fatigue-resistant photoswitchable GPCR antagonist.
价 格:¥电议型 号:T69774产 地:中国大陆
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T68774Deterenol Free Base;化合物 Deterenol Free BaseDeterenol Free Base
Deterenol Free Base is a beta-adrenoceptor agonist. It is an effective nonmydriatic and nonmiotic hypotensive agent, which can be used in antiglaucoma treatment.
价 格:¥电议型 号:T68774产 地:中国大陆
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T67774Compound CDy9;化合物CDy9Compound CDy9
Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.
价 格:¥电议型 号:T67774产 地:中国大陆
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T67749Fuzapladib;化合物FuzapladibIS-741;IS-741
Fuzapladib (IS-741) (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of adhesion molecules (integrin) expressed on the inflammatory cell surface to prevent inflammatory cells from adhering to vascular endothelial cells and infiltrating tissue and to control exacerbation of pancreatitis.
价 格:¥电议型 号:T67749产 地:中国大陆
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T67748ROCK-IN-5;化合物ROCK-IN-5ROCK-IN-5
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC. ROCK-IN-5 exhibits the potential for cardiac, proliferative and neurodegenerative diseases research.
价 格:¥电议型 号:T67748产 地:中国大陆
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T67747CB2R/FAAH modulator-3;化合物CB2R/FAAH modulator-3CB2R/FAAH modulator-3
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 has research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67747产 地:中国大陆
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T67746IMS2186;化合物IMS2186IMS2186
IMS2186 is a reagent with activity of antichoroidal neovascularization (CNV). IMS2186 could arrest cancer cell cycle in G2/M phase, result in exerting anti-proliferation and anti-angiogenesis effects. IMS2186 reduces the amount of eye leakage and diseased cells with no intraocular toxicity.
价 格:¥电议型 号:T67746产 地:中国大陆
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T67745CB2R/FAAHu00A0modulator-2;化合物CB2R/FAAHu00A0modulator-2CB2R/FAAHu00A0modulator-2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67745产 地:中国大陆
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T67743Isonicotinaldehyde 2-pyridinylhydrazone;化合物 Isonicotinaldehyde 2-pyridinylhydrazoneIsonicotinaldehyd
4-Pyridinecarboxaldehyde, 2-(2-pyridinyl)hydrazone, [C(E)]- is a ligand of mixed-ligand coordination polymer [Zn4(bdc)4(ppmh)2(H2O)]n.
价 格:¥电议型 号:T67743产 地:中国大陆
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T67742EX-A5386;肾上腺糖皮质激素受体调节剂1Glucocorticoid receptor modulator-1;Glucocorticoid receptor modulator-1
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.
价 格:¥电议型 号:T67742产 地:中国大陆