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  • T67741SU056；化合物SU056SU056

    SU056 is a YB-1 inhibitor. SU056 interacts with YB-1 and inhibits and downstream proteins and pathways. SU056 can induce cell-cycle arrest, apoptosis, and inhibit cell migration in ovarian cancer cells.

    价 格：￥电议型 号：T67741产 地：中国大陆

  • T6774AZD-8835；化合物AZD8835AZD8835；AZD8835

    AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).

    价 格：￥电议型 号：T6774产 地：中国大陆

  • T66774N-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)acetamide；化合物 N-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)acet

    N-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)acetamide is a useful organic compound for research related to life sciences. The catalog number is T66774 and the CAS number is 560075-65-2.

    价 格：￥电议型 号：T66774产 地：中国大陆

  • T6651Safinamide mesylate；沙芬酰胺甲磺酸盐PNU-151774E,FCE28073|||PNU-151774E|||NW-1015|||EMD 1195686 mesylate；PNU-

    Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.

    价 格：￥电议型 号：T6651产 地：中国大陆

  • T65774(2R,3S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoic acid；化合物 (2R,3S)-2-((((9H-Fl

    (2R,3S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65774 and the CAS number is 157355-81-2.

    价 格：￥电议型 号：T65774产 地：中国大陆

  • T647742-Aminopent-4-ynoic acid；化合物 2-Aminopent-4-ynoic acid2-Aminopent-4-ynoic acid

    2-Aminopent-4-ynoic acid is a useful organic compound for research related to life sciences. The catalog number is T64774 and the CAS number is 50428-03-0.

    价 格：￥电议型 号：T64774产 地：中国大陆

  • T63774EGFR-IN-58；化合物 EGFR-IN-58EGFR-IN-58

    EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.

    价 格：￥电议型 号：T63774产 地：中国大陆

  • T62774BS-181 dihydrochloride；化合物 BS-181 dihydrochlorideBS-181 dihydrochloride

    BS-181 dihydrochloride is a selective and potent inhibitor of CDK7 with an IC50 value of 21 nM. BS-181 dihydrochloride inhibits CDK2 (IC50: 880 nM), CDK5 (IC50: 3000 nM) and CDK9 (IC50: 4200 nM), but does not block CDK1, 4 and 6. BS-181 dihydrochloride inhibits the growth of a group of cancer cells (IC50: 11.5 μM-37.3 μM) and induces apoptosis.

    价 格：￥电议型 号：T62774产 地：中国大陆

  • T62132S-777469；化合物 S-777469S-777469

    S-777469 is a selective, orally active agonist of the cannabinoid type 2 receptor (CB2) (Ki: 36 nM). s-777469 significantly inhibited compound 48/80-induced scratching behaviour in mice in a dose-dependent manner. s-777469 excites CB2, inhibits pruritic signalling and shows an anti-pruritic effect.

    价 格：￥电议型 号：T62132产 地：中国大陆

  • T61774SARS 3CLpro-IN-1；化合物 SARS 3CLpro-IN-1SARS 3CLpro-IN-1

    SARS 3CLpro-IN-1 (Compound 3b) is a stereo-specific SARS 3CL protease inhibitor that belongs to the octahydroisochromene scaffold. It demonstrates inhibition against the P1 site imidazole, with an IC50 value of 95 μM [1].

    价 格：￥电议型 号：T61774产 地：中国大陆

  • T61151Beclobrate；贝罗贝特Sgd 24774；Sgd 24774

    Beclobrate (Sgd 24774) is a novel orally available fibric acid derivative that has shown significant lipid and cholesterol-lowering activity in rodents and may be used in the study of primary hyperlipoproteinemia.

    价 格：￥电议型 号：T61151产 地：中国大陆

  • T60774NITD-916；化合物NITD-916NITD916|||NITD 916；NITD916|||NITD 916

    NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.

    价 格：￥电议型 号：T60774产 地：中国大陆

  • T5774Demethylsuberosin；7-去甲基软木花椒素7-demethylsuberosin；7-去甲基软木花椒素|||7-demethylsuberosin

    7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory effects on PGE2 production with the IC50 values of 9.42 μM.

    价 格：￥电议型 号：T5774产 地：中国大陆

  • T5537IDF-11774；化合物IDF-11774IDF-11774

    IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).

    价 格：￥电议型 号：T5537产 地：中国大陆

  • T39774Bis-CH2-PEG2-acid；Bis-CH2-PEG2-acidBis-CH2-PEG2-acid；Bis-CH2-PEG2-acid

    Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T39774产 地：中国大陆

  • T38986Fitusiran；FitusiranALN-AT3SC|||SAR439774；ALN-AT3SC|||SAR439774

    Fitusiran (ALN-AT3SC) is a small interfering RNA compound designed to selectively bind to antithrombin (AT) messenger RNA in the liver, leading to decreased AT production. By doing so, Fitusiran enhances thrombin generation, making it a promising candidate for hemophilia research.

    价 格：￥电议型 号：T38986产 地：中国大陆

  • T38774E67-2E67-2E67-2

    E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and histone H3 lysine 4 (H3K4) demethylase.

    价 格：￥电议型 号：T38774产 地：中国大陆

  • T37774Thielavin A；Thielavin AThielavin A

    Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).

    价 格：￥电议型 号：T37774产 地：中国大陆

  • T37749Benanomicin A；Benanomicin ABenanomicin A

    Benanomicin A is a microbial metabolite that has been found inActinomycetesand has antifungal, fungicidal, and antiviral activities.1,2It is active against a variety of mammalian and plant pathogenic fungi, includingC. albicans,T. mentagrophytes,C. neoformans,P. oryzae, andA. niger(MICs = 3.13-50 μg/ml).1Benanomicin A inhibits HIV-1 viral infection in MT-4 cells in a concentration-dependent manner.2

    价 格：￥电议型 号：T37749产 地：中国大陆

  • T37748Ivermectin B1b；Ivermectin B1bIvermectin B1b

    Ivermectin B1b is the minor component . It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function.

    价 格：￥电议型 号：T37748产 地：中国大陆

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