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T72528NSC243928 mesylate;NSC243928 甲磺酸盐NSC243928 mesylate
NSC243928 mesylate binds to human lymphocyte antigen 6 (LY6), a cell growth inhibitor with anticancer activity, and induces cell death in triple-negative breast cancer cells in a LY6K-dependent manner.
价 格:¥电议型 号:T72528产 地:中国大陆
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T72317CEP-28122 mesylate salt;化合物 CEP-28122 mesylate saltCEP-28122 mesylate salt
CEP-28122 mesylate salt, a diaminopyrimidine derivative, serves as a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) inhibitor, exhibiting an IC 50 value of 1.9 nM against recombinant ALK kinase activity. It demonstrates antitumor efficacy in ALK-positive human cancer experimental models and possesses favorable pharmacodynamic and pharmacokinetic profiles.
价 格:¥电议型 号:T72317产 地:中国大陆
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T72209(R,R)-Reboxetine mesylate;化合物 (R,R)-Reboxetine mesylate(R,R)-FCE20124 mesylate ; (R,R)-PNU155950E m
(R,R)-Reboxetine mesylate, an antidepressant agent, exhibits high bioavailability and is the (R,R) enantiomer of Reboxetine, a selective noradrenaline reuptake inhibitor. Contrasting its counterpart, the (S,S) enantiomer, this compound demonstrates low affinity for alpha-adrenergic and muscarinic receptors, alongside low toxicity in animals.
价 格:¥电议型 号:T72209产 地:中国大陆
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T72207Larotinib mesylate hydrate;化合物 Larotinib mesylate hydrateLarotinib mesylate hydrate
Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nM.
价 格:¥电议型 号:T72207产 地:中国大陆
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T7212Delavirdine mesylate;化合物Delavirdine (mesylate)U 90152 (mesylate)|||BHAP-U 90152 (mesylate)|||Delavir
Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
价 格:¥电议型 号:T7212产 地:中国大陆
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T7175Alflutinib mesylate;甲磺酸伏美替尼AST2818 mesylate;甲磺酸伏美替尼|||AST2818 mesylate
Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.
价 格:¥电议型 号:T7175产 地:中国大陆
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T71699Lanopepden mesylate;拉诺普登甲磺酸盐GSK 1322322 mesylate|||GSK-1322322J mesylate;GSK 1322322 mesylate|||GSK-
Lanopepden mesylate is a peptide deformylase inhibitor against Staphylococcus aureus.
价 格:¥电议型 号:T71699产 地:中国大陆
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T71578Endoxifen mesylate;化合物 Endoxifen mesylateEndoxifen mesylate
Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and other psychotic disorders. Endoxifen is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group. It is an active metabolite of tamoxifen and has been found to be effective in patients that have failed previous hormonal therapies (tamoxifen, aromat
价 格:¥电议型 号:T71578产 地:中国大陆
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T71148PWT33597 mesylate;化合物 PWT33597 mesylatePWT33597 mesylate
PWT33597, also known as VDC-597, is an orally bioavailable dual inhibitor of phosphatidylinositide 3-kinase (PI3K) alpha and mammalian target of rapamycin (mTOR) kinase with potential antineoplastic activity. PI3K alpha/mTOR dual inhibitor PWT33597 selectively inhibits both PI3K alpha kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in PI3K/mTOR-overexpressing tumor cells.
价 格:¥电议型 号:T71148产 地:中国大陆
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T71138Binospirone mesylate;化合物 Binospirone mesylateBinospirone mesylate
Binospirone mesylate is a putative 5-HT(1A) receptor antagonist.
价 格:¥电议型 号:T71138产 地:中国大陆
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T7112Ibutamoren Mesylate;伊布莫仑甲磺酸盐MK-0677|||MK-677;MK-0677|||伊布莫仑甲磺酸盐|||MK-677
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
价 格:¥电议型 号:T7112产 地:中国大陆
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T71003Infigratinib mesylate;化合物 Infigratinib mesylateInfigratinib mesylate
Infigratinib mesylate, also known as, BGJ398 mesylate or NVP-BGJ398 mesylate, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Infigratinib me
价 格:¥电议型 号:T71003产 地:中国大陆
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T70997Fonazine mesylate;化合物 Fonazine mesylateFonazine mesylate
Fonazine mesylate is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.
价 格:¥电议型 号:T70997产 地:中国大陆
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T70759CUDC-907 mesylate;化合物 CUDC-907 mesylateCUDC-907 mesylate
CUDC-907 mesylate is a small molecule inhibitor of histone deacetylase and PI3 kinase developed by Curis. It is investigated in clinical trials for the treatment of relapsed or refractory lymphomas, thyroid cancer, multiple myeloma, breast cancer and other malignancies.
价 格:¥电议型 号:T70759产 地:中国大陆
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T70661Azalanstat mesylate;化合物 Azalanstat mesylateAzalanstat mesylate
Azalanstat mesylate is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor. Azalanstat mesylate has been shown to inhibit cholesterol synthesis in HepG2 cells, human fibroblasts, hamster hepatocytes and hamster liver, by inhibiting the cytochrome P450 enzyme lanosterol 14 alpha-demethylase. When administered orally to hamsters fed regular chow, RS-21607 (50 mg/kg/day) lowered serum cholesterol in a dose-dependent manner (ED50 = 62 mg/kg) in a period of 1 week. It preferentially
价 格:¥电议型 号:T70661产 地:中国大陆
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T70609Bisnafide mesylate;化合物 Bisnafide mesylateBisnafide mesylate
Bisnafide is a Naphthalimide Analogue that acts as DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent. Antiangiogenic agents can normalize tumor vessels and promote the delivery of cytotoxic agents to tumor sites.
价 格:¥电议型 号:T70609产 地:中国大陆
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T70461Pralidoxime mesylate;化合物 Pralidoxime mesylatePralidoxime mesylate
Pralidoxime mesylate is a Cholinesterase Reactivator
价 格:¥电议型 号:T70461产 地:中国大陆
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T70358Gepotidacin mesylate dihydrate;化合物 Gepotidacin mesylate dihydrateGepotidacin mesylate dihydrate
Gepotidacin mesylate dihydrate, also known as GSK-2140944 mesylate dihydrate, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin mesylate dihydrate is a novel antibacterial drug candidate. Gepotidacin mesylate dihydrate Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin mesylate dihydrate is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution,
价 格:¥电议型 号:T70358产 地:中国大陆
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T7026LKukoamine B mesylate;地骨皮乙素 甲磺酸盐KukoamineBmesylate|||KukoamineBmesylate;KukoamineBmesylate|||Kukoamin
Kukoamine B mesylate is a novel cationic alkaloid derived from dermatophytes with antioxidant activity, inhibits LPS internalization in Kupffer and RAW 264.7 cells, and can be used to study acute inflammation and diabetes.
价 格:¥电议型 号:T7026L产 地:中国大陆
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T70152Miransertib mesylate;化合物 Miransertib mesylateMiransertib mesylate
Miransertib mesylate is a selective AKT inhibitor that binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K/AKT signaling pathway. This may result in reduction in tumor cell proliferation and the induction of tumor cell apoptosis.
价 格:¥电议型 号:T70152产 地:中国大陆