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T8728DMU-2139;化合物DMU2139DMU-2139
DMU2139 is a specific CYP1B1 inhibitor (CYP1B1 and CYP1A1 with IC50 of 9 nM and 795 nM, respectively).
价 格:¥电议型 号:T8728产 地:中国大陆
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T83950ARN 11391;化合物 ARN 11391ARN 11391
ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion signaling by directly targeting ITPR1. Furthermore, ARN 11391 amplifies calcium signaling in cells with mutant ITPR1 linked to SCA29, a variant of spinocerebellar ataxia.
价 格:¥电议型 号:T83950产 地:中国大陆
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T83690[Leu144, Arg147]-PLP (139-151) TFA;化合物 [Leu144, Arg147]-PLP (139-151) TFA[Leu144, Arg147] Proteolipi
[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing mice with this peptide (50 ?g) mixed in complete Freund’s adjuvant (CFA) elevates IL-4 levels in the spleen. While it suppresses Th1 cell activation in vitro, it does not do so in vivo; instead, it promotes the development of regulatory T cells. Preimmunization with [Leu144, Arg14
价 格:¥电议型 号:T83690产 地:中国大陆
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T83139Aloeresin J;化合物 Aloeresin JAloeresin J
Aloeresin J (compound 10) is a chromone isolated from the ethanol extract of Aloe vera leaf bark.
价 格:¥电议型 号:T83139产 地:中国大陆
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T82266GPR139 agonist-2;化合物 GPR139 agonist-2GPR139 agonist-2
GPR139 agonist-2 (compound 20a), a potent GPR139 agonist with an EC50 of 24.7 nM, has demonstrated efficacy in rescuing social interaction deficits and alleviating cognitive deficits in murine schizophrenia models, indicating its potential in antischizophrenia drug research [1].
价 格:¥电议型 号:T82266产 地:中国大陆
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T82139Hypolaetin 7-glucoside;化合物 Hypolaetin 7-glucosideHypolaetin 7-glucoside
Hypolaetin 7-glucoside, a flavone glucoside, is present in the berries of Juniperus macropoda [1].
价 格:¥电议型 号:T82139产 地:中国大陆
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T8182LGuan-fu base A hydrochloride(1394-48-5 free base);化合物Guan-fu base A hydrochlorideGuan-fu base A hydr
Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms.
价 格:¥电议型 号:T8182L产 地:中国大陆
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T81399PRMT4-IN-2;化合物 PRMT4-IN-2PRMT4-IN-2
PRMT4-IN-2 (compound 55) acts as a pan-inhibitor across various protein arginine methyltransferase (PRMT) isoforms, exhibiting inhibitory potencies with IC50 values of 92 nM for PRMT4, 436 nM for PRMT6, 460 nM for PRMT1, 823 nM for PRMT8, and 1.386 μM for PRMT3 [1].
价 格:¥电议型 号:T81399产 地:中国大陆
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T81397Procyanidin C2;化合物 Procyanidin C2Procyanidine C2;Procyanidine C2
Procyanidin C2, a phenolic glycoside, is derived from Fagopyrum dibotrys (D. Don) Hara [1].
价 格:¥电议型 号:T81397产 地:中国大陆
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T81396PRO-F;化合物 PRO-FPRO-F
PRO-F, a photoactivable hydrogen sulfide (H2S) donor, possesses reactive oxygen species (ROS) scavenging properties and emits a fluorescent signal upon light activation, enabling real-time tracking of H2S release. Its activation is independent of endogenous substance consumption and facilitates intracellular H2S delivery, safeguarding cells from excessive ROS-induced damage. Notably, PRO-F has demonstrated efficacy in promoting chronic wound healing in diabetic models [1].
价 格:¥电议型 号:T81396产 地:中国大陆
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T81395Progenin III palmitate;化合物 Progenin III palmitateProgenin III palmitate
Progenin III palmitate, a steroid glycoside ester, is isolated from the rhizomes of Dioscorea cayenensis [1].
价 格:¥电议型 号:T81395产 地:中国大陆
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T81394PRO-HD1;化合物 PRO-HD1PRO-HD1
PRO-HD1, a PROTAC (proteolysis-targeting chimera) HDAC6 degrader, effectively degrades HDAC6 in A549 cells and inhibits Jurkat cell proliferation with an IC50 of 5.8 ?M [1].
价 格:¥电议型 号:T81394产 地:中国大陆
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T81393PRO-HD2;化合物 PRO-HD2PRO-HD2
PRO-HD2 is a selective, PROTAC-based degrader of HDAC6 [1].
价 格:¥电议型 号:T81393产 地:中国大陆
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T81392PRO-HD3;化合物 PRO-HD3PRO-HD3
PRO-HD3 is a cell-specific, PROTAC-based degrader targeting HDAC6 [1].
价 格:¥电议型 号:T81392产 地:中国大陆
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T81391Prolactin-Releasing Peptide (12-31), rat;化合物 Prolactin-Releasing Peptide (12-31), ratProlactin-Relea
Prolactin-Releasing Peptide (12-31), rat, a fragment of PrRP, exhibits high affinity for GPR10 receptors and stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor [1] [2].
价 格:¥电议型 号:T81391产 地:中国大陆
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T81390Prolactin-Releasing Peptide (1-31) (rat);化合物 Prolactin-Releasing Peptide (1-31) (rat)Prolactin-Relea
Prolactin-Releasing Peptide (1-31) (rat) serves as a ligand for the UHR-1/GRP10 receptor, moderating fasting-induced food intake and elevating plasma concentrations of LH, FSH, and testosterone in rats [1] [2].
价 格:¥电议型 号:T81390产 地:中国大陆
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T8139Sulfamethoxazole sodium;磺胺甲恶唑钠Ro 4-2130 sodium;新诺明钠|||Ro 4-2130 sodium|||磺胺甲恶唑钠
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic
价 格:¥电议型 号:T8139产 地:中国大陆
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T81139SNNF(N-Me)GA(N-Me)IL;化合物 SNNF(N-Me)GA(N-Me)ILSNNF(N-Me)GA(N-Me)IL
SNNF(N-Me)GA(N-Me)IL is a biologically active peptide comprising double N-methylated derivatives of a partial IAPP sequence known to be amyloidogenic and cytotoxic.
价 格:¥电议型 号:T81139产 地:中国大陆
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T80771WRR139;化合物 WRR139WRR139
WRR139, a peptide vinyl sulfone, plays a role in disease processes including inflammation and cancer, and acts as an inhibitor of cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1. Moreover, WRR139 amplifies the cytotoxic effects of Carfilzomib on cancer cells [1].
价 格:¥电议型 号:T80771产 地:中国大陆
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T80139CRAMP-18 (mouse);化合物 CRAMP-18 (mouse)CRAMP-18 (mouse)
CRAMP-18 (mouse) is an antibiotic peptide with demonstrated efficacy against Gram-negative bacteria, including S. typhimurium and P. aeruginosa, while exhibiting no hemolytic activity. This compound shows promise for research into antifungal, antibacterial, and antitumor applications [1] [2].
价 格:¥电议型 号:T80139产 地:中国大陆