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T61895AZD7254;化合物 AZD7254AZD7254
AZD7254 is an oral effective Smoothened (SMO) inhibitor, and the EC50 of sonic Hh protein (shh) is 1.0 nM.
价 格:¥电议型 号:T61895产 地:中国大陆
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T61254CDK1/Cyc B-IN-1;化合物 CDK1/Cyc B-IN-1CDK1/Cyc B-IN-1
CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
价 格:¥电议型 号:T61254产 地:中国大陆
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T6042[11C]MP 10;化合物PF-2545920Mardepodect|||PF-2545920;Mardepodect|||PF-2545920
[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.
价 格:¥电议型 号:T6042产 地:中国大陆
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T60254Calcium glycerophosphate;甘油磷酸钙Calcium glycerophosphate
Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2].
价 格:¥电议型 号:T60254产 地:中国大陆
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T5S2254Swertianolin;当药醇苷Bellidifolin-8-O-Glucoside;Bellidifolin-8-O-Glucoside|||当药醇苷
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin and swertiamarin show significant hepatoprotective effect in the liver damage model induced by alpha-naphthylisot hiocyanate. 3. Swertianolin shows anti-acetylcholinesterase activity effects. 4. Swertianolin shows that it can scavenge superoxide and hydroxyl radicals with the st
价 格:¥电议型 号:T5S2254产 地:中国大陆
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T5254Glycodeoxycholate Sodium;脱氧甘胆酸钠Sodium glycyldeoxycholate|||Sodium glycodeoxycholate|||Glycodeoxychol
Glycodeoxycholate Sodium (Glycodeoxycholic acid sodium salt) induces Apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment.
价 格:¥电议型 号:T5254产 地:中国大陆
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T5124SRT 1720 dihydrochloride[925434-55-5(free base)];化合物SRT 1720 dihydrochloride[SRT 1720 dihydrochlorid
SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).
价 格:¥电议型 号:T5124产 地:中国大陆
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T4485Lazertinib;化合物LazertinibLazertinib (YH25448)|||GNS-1480|||YH25448;Lazertinib (YH25448)|||GNS-1480|||
Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.
价 格:¥电议型 号:T4485产 地:中国大陆
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T4254TM5441;化合物TM5441TM5441
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1).
价 格:¥电议型 号:T4254产 地:中国大陆
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T4211SAG hydrochloride (912545-86-9(free base));化合物SAG hydrochlorideSmoothened Agonist HCl;Smoothened Ago
SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.
价 格:¥电议型 号:T4211产 地:中国大陆
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T41189AY 254;AY 254AY 254
AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro.
价 格:¥电议型 号:T41189产 地:中国大陆
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T40254MRTX-1719;化合物MRTX-1719MRTX-1719
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
价 格:¥电议型 号:T40254产 地:中国大陆
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T4019Cambinol;化合物CambinolSIRT1/2 Inhibitor IV|||NSC 112546;SIRT1/2 Inhibitor IV|||NSC 112546
Cambinol (SIRT1/2 Inhibitor IV) is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 μM, respectively) in a substrate-, but not NAD-, competitive manner. Cambinol inhibits SIRT5 deacetylase activity only at much higher concentrations (IC50 >300 μM) and no inhibitory for the class I and II HDACs. In BCL6-expressing Burkitt lymphoma cell lines, Cambinol-induced apoptosis has been attributed to the hyperacetylation of p53 and BCL6.Camb
价 格:¥电议型 号:T4019产 地:中国大陆
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T39254ICG-carboxylic acid;ICG-carboxylic acidICG-carboxylic acid
ICG-carboxylic acid is a fluorescent probe in the near-infrared (NIR) range. It is derived from indocyanine green (ICG), a commonly used fluorescent dye in medical diagnostics. ICG exhibits a peak absorption at 800 nm, allowing it to efficiently absorb energy from near-infrared lasers and release heat within the dyed tissue.
价 格:¥电议型 号:T39254产 地:中国大陆
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T37254Rugulotrosin A;Rugulotrosin ARugulotrosin A
Rugulotrosin A is an antibiotic originally isolated from Penicillium. It is active against the Gram-positive bacteria E. faecalis, B. cereus, B. subtilis, and S. aureus with 99% lethal dose (LD99) values of 1.6, 3.1, 5.5, and 200 μg/ml, respectively. Rugulotrosin A is inactive against Gram-negative bacteria.
价 格:¥电议型 号:T37254产 地:中国大陆
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T36254dTAGV-1 hydrochloride;dTAGV-1 hydrochloridedTAGV-1 hydrochloride
Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-NEG also available. Important: It is recommended that DMSO stock solutions of this compound are made and used on the same day and are not subjected to freeze/thaw.
价 格:¥电议型 号:T36254产 地:中国大陆
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T35254YM 11133;化合物 T35254YM-11133|||YM11133;YM-11133|||YM11133
YM 11133 is a biochemical.
价 格:¥电议型 号:T35254产 地:中国大陆
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T34590SD-254;化合物 T34590Venlafaxine deuterium-substituted|||D9-venlafaxine;Venlafaxine deuterium-substitute
SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.
价 格:¥电议型 号:T34590产 地:中国大陆
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T34254Radalbuvir;化合物 T34254GS-9669|||GS 9669|||GS9669;GS-9669|||GS 9669|||GS9669
Radalbuvir (GS-9669) is an investigational antiviral agent for the treatment of hepatitis C virus (HCV) infection as an NS5B inhibitor.
价 格:¥电议型 号:T34254产 地:中国大陆
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T34084Plastoquinone;化合物 T34084Q 254|||Q-254|||Q254;Q 254|||Q-254|||Q254
Plastoquinone is a polyunsaturated side-chain quinone derivative which is an important link in the electron transport chain of green plants during the photosynthetic conversion of light energy by photophosphorylation into the potential energy of chemical bonds.
价 格:¥电议型 号:T34084产 地:中国大陆