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  • T13882SCH00013SCH00013

    SCH00013 is an agent of cardiotonic that primarily acts via an increase in myofibrillar Ca++ sensitivity. SCH00013 have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.

    价 格：￥电议型 号：T13882产 地：美洲

  • T16932SRT 2183SRT 2183

    SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM).

    价 格：￥电议型 号：T16932产 地：美洲

  • T1801SR9243SR9243

    SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect.

    价 格：￥电议型 号：T1801产 地：美洲

  • T2293SGX-523SGX-523,SGX523,SGX 523

    SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, and c-Raf.

    价 格：￥电议型 号：T2293产 地：美洲

  • T2417Sal003Sal003

    Sal003, an effective cell-permeable analog,inhibitis the eIF2α phosphatase.

    价 格：￥电议型 号：T2417产 地：美洲

  • T5683(2R,3S)-3-Phenylisoserine hydrochloride(2R,3S)-3-Phenylisoserine hydrochloride

    NA

    价 格：￥电议型 号：T5683产 地：美洲

  • T8478SC-43；化合物SC-43SC-43

    SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.

    价 格：￥电议型 号：T8478产 地：中国大陆

  • T83599(+)-Leucocyanidin；化合物 (+)-Leucocyanidin2,3-trans-3,4-trans-Leucocyanidin|||(2R,3S,4R)-Leucocyanidin|

    (+)-Leucocyanidin, an isoform of leucocyanidin and potent anti-ulcerogenic agent, has been extracted from Litchi chinensis. This compound exhibits considerable protective properties in rat models against aspirin-induced gastric erosions [1].

    价 格：￥电议型 号：T83599产 地：中国大陆

  • T83558(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9

    (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a palmitate derivative, is extracted from the root of Salvia miltiorrhiza. Compound 3 exhibits anti-cancer properties, demonstrating half-maximal cytotoxic concentrations (DC50s) of 25.5 μg/mL against HeLa, 37.5 μg/mL against HepG2, and 30.2 μg/mL against OVCAR-3 human cancer cell lines [1].

    价 格：￥电议型 号：T83558产 地：中国大陆

  • T83557(3S,4S)-Tivantinib；化合物 (3S,4S)-TivantinibARQ 198|||(3S,4S)-ARQ 197；ARQ 198|||(3S,4S)-ARQ 197

    (3S,4S)-Tivantinib, a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET, targets GSK3α and GSK3β—two novel enzymes implicated in the pathogenesis of non-small cell lung cancer (NSCLC) [1].

    价 格：￥电议型 号：T83557产 地：中国大陆

  • T8344217(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene；化合物 17(13→14)-Abeo-ent-3S*,13S*,16-trihydro

    17(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene is a sesquiterpene lactone of natural origin that exhibits anti-inflammatory properties [1].

    价 格：￥电议型 号：T83442产 地：中国大陆

  • T81208SARS-CoV-2-IN-63；化合物 SARS-CoV-2-IN-63SARS-CoV-2-IN-63

    SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication within Vero E6 cells and Calu-3 cells, yielding half-maximal effective concentration (EC50) values of 1.99 μM and 1.92 μM, respectively [1].

    价 格：￥电议型 号：T81208产 地：中国大陆

  • T81197SBP-3；化合物 SBP-3SBP-3

    SBP-3, a sulfite bioluminescent probe (SBP), employs a sulfite-mediated intramolecular cleavage reaction [1] for sulfite detection.

    价 格：￥电议型 号：T81197产 地：中国大陆

  • T81151SK-MLCK M13；化合物 SK-MLCK M13SK-MLCK M13

    SK-MLCK M13 is a biologically active peptide representing the calmodulin (CaM)-binding domain of CaM target proteins, where CaM is a ubiquitous Ca2+ binding protein.

    价 格：￥电议型 号：T81151产 地：中国大陆

  • T81146SMP-33693；化合物 SMP-33693SMP-33693

    SMP-33693 is an Antibody-Drug Conjugate (ADC) known for its low payload shedding rate and demonstrated in vivo tumor inhibition in ovarian, gastric, and breast cancers [1].

    价 格：￥电议型 号：T81146产 地：中国大陆

  • T81143SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3；化合物 SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3SN38-PAB-Lys(MM

    "SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a drug-linker conjugate for antibody-drug conjugates (ADCs), consisting of the anti-cancer agent SN38 linked to Lys(MMT)-PAB-oxydiacetamide-PEG8-N3. It serves as a click chemistry reagent featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-bearing molecules and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds containing DBCO or BCN groups, facilitating t

    价 格：￥电议型 号：T81143产 地：中国大陆

  • T81056SWTX-143；化合物 SWTX-143SWTX-143

    SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional activity of the YAP/TAZ-TEAD complex and demonstrating antitumor activity [1].

    价 格：￥电议型 号：T81056产 地：中国大陆

  • T81053T3SS-IN-3；化合物 T3SS-IN-3T3SS-IN-3

    T3SS-IN-3 (compound F-24) serves as an inhibitor specific to the type III secretion system (T3SS), significantly reducing the transcription of the hrpY gene while not impeding bacterial growth [1].

    价 格：￥电议型 号：T81053产 地：中国大陆

  • T80381SAAP Fraction 3；化合物 SAAP Fraction 3SAAP Fraction 3

    SAAP Fraction 3, an antimicrobial peptide, exhibits activity against P. haemolytica in Zn-saline buffer [1].

    价 格：￥电议型 号：T80381产 地：中国大陆

  • T79689SIRT6-IN-3；化合物 SIRT6-IN-3SIRT6-IN-3

    SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts apoptosis. It enhances the responsiveness of cancer cells to gemcitabine by obstructing the DNA damage repair pathway, thus serving as a valuable tool in pancreatic cancer research [1].

    价 格：￥电议型 号：T79689产 地：中国大陆

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