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T7959(+)-ISOPINOCAMPHEOL;(1S,2S,3S,5R)-(+)-异松蒎醇(+)-ISOPINOCAMPHEOL
(+)-ISOPINOCAMPHEOL is a natural product.
价 格:¥电议型 号:T7959产 地:中国大陆
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T79564Sirt1/2-IN-3;化合物 Sirt1/2-IN-3Sirt1/2-IN-3
Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 μM (SIRT1) and 2.0 μM (SIRT2), respectively. This compound effectively inhibits p53 deacetylation while simultaneously elevating p53 and α-tubulin acetylation levels. Additionally, Sirt1/2-IN-3 promotes apoptosis and exhibits antiproliferative effects on human leukemia cell lines [1].
价 格:¥电议型 号:T79564产 地:中国大陆
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T79542SGC-UBD253;化合物 SGC-UBD253SGC-UBD253
SGC-UBD253 is a potent antagonist of the HDAC6-UBD interaction and may be utilized in cancer research [1].
价 格:¥电议型 号:T79542产 地:中国大陆
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T7945SU14813;化合物SU14813SU14813
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).
价 格:¥电议型 号:T7945产 地:中国大陆
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T79396T3SS-IN-2;化合物 T3SS-IN-2T3SS-IN-2
T3SS-IN-2 (Compound 2h) serves as an inhibitor of the type three secretion system (T3SS), with applications in bacterial infection research [1].
价 格:¥电议型 号:T79396产 地:中国大陆
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T79310SARS-CoV-2-IN-53;化合物 SARS-CoV-2-IN-53SARS-CoV-2-IN-53
ARS-CoV-2-IN-53 (Compd 5d) exhibits an inhibitory effect on SARS-CoV-2 replication, with an effective concentration (EC50) value of 14.3 μM, and demonstrates notable antiviral activity against human coronavirus 229E (HCoV-229E) [1].
价 格:¥电议型 号:T79310产 地:中国大陆
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T79243SARS-CoV-2-IN-43;化合物 SARS-CoV-2-IN-43SARS-CoV-2-IN-43
Compound 8h, also known as SARS-CoV-2-IN-43, is a powerful inhibitor effective in obstructing the replication of SARS-CoV-2, exhibiting significant antiviral activity [1].
价 格:¥电议型 号:T79243产 地:中国大陆
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T79238SDH-IN-3;化合物 SDH-IN-3SDH-IN-3
SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor, demonstrating potent antifungal activity with an inhibition concentration (IC50) of 7.2 μg/mL and an effective concentration (EC50) of 1.9 μg/mL against Nigrospora oryzae. This compound is valuable for anti-infection research [1].
价 格:¥电议型 号:T79238产 地:中国大陆
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T79186STAT6-IN-3;化合物 STAT6-IN-3STAT6-IN-3
STAT6-IN-3 (Compound 18a) serves as an inhibitor of STAT6 with an IC50 value of 44 nM, specifically targeting the Src Homology 2 (SH2) domain. It is utilized in research studies focused on inflammatory disorders, including asthma [1].
价 格:¥电议型 号:T79186产 地:中国大陆
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T79106SORT-PGRN interaction inhibitor 3;化合物 SORT-PGRN interaction inhibitor 3SORT-PGRN interaction inhibit
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study of neurodegenerative diseases [1].
价 格:¥电议型 号:T79106产 地:中国大陆
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T78930T3SS-IN-1;化合物 T3SS-IN-1T3SS-IN-1
T3SS-IN-1 (compound B9) is a potent type III secretion system (T3SS) inhibitor that also suppresses hpa1 promoter activity and harpin protein expression, without impacting bacterial growth [1].
价 格:¥电议型 号:T78930产 地:中国大陆
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T78725SARS-CoV-2 nsp14-IN-3;化合物 SARS-CoV-2 nsp14-IN-3SARS-CoV-2 nsp14-IN-3
SARS-CoV-2 nsp14-IN-3 (4975) is a potent inhibitor targeting the N7-Methyltransferase activity of SARS-CoV-2 nonstructural protein 14 (Nsp14), with an IC50 value of 3.5 μM [1].
价 格:¥电议型 号:T78725产 地:中国大陆
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T78694SHP2-IN-13;化合物 SHP2-IN-13SHP2-IN-13
SHP2-IN-13 is an orally active, highly selective allosteric inhibitor targeting the SHP2 “tunnel site,” exhibiting an IC50 of 83.0 nM. It holds potential for research into cancers with RTK oncogenic drivers and diseases associated with SHP2.
价 格:¥电议型 号:T78694产 地:中国大陆
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T78604SLC26A3-IN-3;化合物 SLC26A3-IN-3SLC26A3-IN-3
SLC26A3-IN-3 (compound 4az), a potent SLC26A3 inhibitor with an IC50 of 40 nM, is utilized for constipation and cystic fibrosis research [1].
价 格:¥电议型 号:T78604产 地:中国大陆
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T77933SJ995973;化合物 SJ995973SJ995973
SJ995973 (PROTAC) represents a highly efficacious degrader of bromodomain and extra-terminal (BET) proteins.
价 格:¥电议型 号:T77933产 地:中国大陆
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T7698BS194化合物BS194(2S,3S)-3-[[3-(异丙基)-7-[(苯基甲基)氨基]吡唑并[1,5-A]嘧啶-5-基]氨基]-1,2,4-丁三醇
BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.
价 格:¥电议型 号:T7698产 地:中国大陆
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T75182GK13S;化合物 GK13SGK13S
G13KS is a deubiquitinase UCHL1 ligand and inhibitor. G13KS inhibits recombinant and cellular UCHL1. G13KS reduces levels of monoubiquitin in human glioblastoma cells [1] .
价 格:¥电议型 号:T75182产 地:中国大陆
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T74974SQ-3;化合物 SQ-3SQ-3
SQ-3, a quinoline analogue, demonstrates moderate selectivity towards α-synuclein aggregates (α-syn aggregates) (K i = 39.3 nM) over β-amyloid (Aβ) aggregates (K i = 230 nM). [18 F]SQ-3 exhibits foundational characteristics as a potential lead compound in developing an effective α-synuclein imaging probe [1].
价 格:¥电议型 号:T74974产 地:中国大陆
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T74807SARS-CoV-2 3CLpro-IN-13;化合物 SARS-CoV-2 3CLpro-IN-13SARS-CoV-2 3CLpro-IN-13
SARS-CoV-2 3CLpro-IN-13 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating significant anti-coronavirus activity with an IC50 value of 21 nM [1].
价 格:¥电议型 号:T74807产 地:中国大陆
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T74268STING agonist-13;化合物 STING agonist-13STING agonist-13
STING Agonist-13, a stimulator of interferon genes (STING) agonist, enhances cancer immunity through STING-mediated immune activation. It activates STING downstream signaling to promote type I interferon immune responses, significantly reduces tumor volume, and exhibits immunological memory-derived cancer inhibition [1].
价 格:¥电议型 号:T74268产 地:中国大陆