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T39753EtavopivatEtavopivatFT-4202
Etavopivat is a powerful, specific, orally bioavailable activator of pyruvate kinase (PKR) in red blood cells (RBCs). It exhibits potent properties against sickling.
价 格：￥电议型 号：T39753产 地：中国大陆
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T39420Oxytocin antiparallel dimer；Oxytocin antiparallel dimerOxytocin antiparallel dimer
Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer.
价 格：￥电议型 号：T39420产 地：中国大陆
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T38909Inotersen sodium；Inotersen sodiumISIS-420915 sodium；ISIS-420915 sodium
Inotersen sodium, also known as ISIS-420915 sodium, is a 2′-O-methoxyethyl-modified antisense oligonucleotide compound. It effectively inhibits transthyretin (TTR) protein production by targeting the TTR RNA transcript, thereby reducing TTR transcript levels. Inotersen sodium holds potential for research on hereditary TTR amyloidosis polyneuropathy.
价 格：￥电议型 号：T38909产 地：中国大陆
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T38420GCPII-IN-1；GCPII-IN-1GCPII-IN-1
GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of 44.3 nanomolar (nM).
价 格：￥电议型 号：T38420产 地：中国大陆
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T3808720-hydroxy Leukotriene B4；20-hydroxy Leukotriene B420-hydroxy Leukotriene B4；20-hydroxy Leukotriene
20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2
价 格：￥电议型 号：T38087产 地：中国大陆
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T37420Ac-ANW-AMC；Ac-ANW-AMCAc-ANW-AMC|||Ac-Ala-Asn-Trp-AMC；Ac-ANW-AMC|||Ac-Ala-Asn-Trp-AMC
Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β5i/LMP7 subunit of the 20S immunoproteasome. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
价 格：￥电议型 号：T37420产 地：中国大陆
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T37114SB 242084 dihydrochloride；SB-242084 (hydrochloride)SB 242084 dihydrochloride
SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.
价 格：￥电议型 号：T37114产 地：中国大陆
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T36420IM-156 acetate；IM-156醋酸盐HL271 acetate；HL271 acetate
IM-156 acetate, an activator of NADH dehydrogenase (IC50=2.2 μM) and AMP-activated protein kinase alpha (AMPKα), is an orally available and bioavailable inhibitor of mitochondrial oxidative phosphorylation (OxPhos).IM-156 acetate increases AMPKα activity and inhibits chlorhexadiene-induced peritoneal fibrosis and inhibit tumor growth in rats .
价 格：￥电议型 号：T36420产 地：中国大陆
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T36397TAN 420E；TAN 420ETAN 420E
TAN 420E is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 μg/ml. TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 μg/ml). It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 μg/ml, respectively).
价 格：￥电议型 号：T36397产 地：中国大陆
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T3623Cobimetinib；考比替尼RG7420|||XL518|||GDC-0973；可美替尼|||考比替尼|||RG7420|||XL518|||GDC-0973
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) phosphorylation and activation and decreased tumor cell proliferation.
价 格：￥电议型 号：T3623产 地：中国大陆
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T35420(S)-p38 MAPK Inhibitor III；(S)-p38 MAPK Inhibitor III(S)-p38 MAPK Inhibitor III；(S)-p38 MAPK Inhibit
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively).
价 格：￥电议型 号：T35420产 地：中国大陆
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T34643Simaomicin alpha；化合物 T34643L D42067alpha|||LL D42067alpha|||LL-D42067alpha；L D42067alpha|||LL D42067
Simaomicin alpha is an actinomycete metabolite isolated from an actinomycete strain.
价 格：￥电议型 号：T34643产 地：中国大陆
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T34420RS-30199；化合物 T34420RS 30199|||RS30199；RS 30199|||RS30199
RS-30199 is a 5-HT1A receptor.
价 格：￥电议型 号：T34420产 地：中国大陆
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T34209Pyroglutamylvaline；化合物 T34209Pyroglutamyl-valine|||Pyro-glu-val|||Pyroglutamyl valine；Pyroglutamyl-v
Pyroglutamylvaline is a dipeptide.
价 格：￥电议型 号：T34209产 地：中国大陆
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T34208Pyroglutamylhistidine；化合物 T34208Pglu-his；Pglu-his
Pyroglutamylhistidine is a dipeptide.
价 格：￥电议型 号：T34208产 地：中国大陆
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T34207Pyroglutamylglutamine diketopiperazine；化合物 T34207Pglu-glu dkm；Pglu-glu dkm
Pyroglutamylglutamine diketopiperazine is a bioactive chemical.
价 格：￥电议型 号：T34207产 地：中国大陆
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T34206Pyroglutaminyl-seryl-leucinamide；化合物 T34206Thyrotropin releasing hormone-AN|||Trh-AN|||Pyr-ser-leu-N
Pyroglutaminyl-seryl-leucinamide is a bioactive chemical.
价 格：￥电议型 号：T34206产 地：中国大陆
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T34205Pyrocatechol, 4-methyl-3,5,6-tribromo-；化合物 T34205Pyrocatechol, 4-methyl-3,5,6-tribromo-
Pyrocatechol, 4-methyl-3,5,6-tribromo- is a bioactive chemical.
价 格：￥电议型 号：T34205产 地：中国大陆
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T34203Pyridine, 2-(5-(p-aminophenoxy)pentyloxy)-；化合物 T34203Pyridine, 2-(5-(p-aminophenoxy)pentyloxy)-
Pyridine, 2-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.
价 格：￥电议型 号：T34203产 地：中国大陆
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T34202Pyridarone；化合物 T34202L 4269|||L-4269|||L 4269;L4269|||L4269|||Piridarona|||Pyridaronum；L 4269|||L-42
Pyridarone is a bioactive chemical.
价 格：￥电议型 号：T34202产 地：中国大陆
