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T77041Iratumumab;化合物 IratumumabIratumumab
Iratumumab (MDX-060), a human anti-CD30 IgG1κ monoclonal antibody, inhibits the growth of CD30-expressing tumor cells and is utilized in the research of Hodgkin´s lymphoma (HL) and anaplastic large-cell lymphoma (ALCL) [1].
价 格:¥电议型 号:T77041产 地:中国大陆
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T77040Iparomlimab;化合物 IparomlimabIparomlimab
Iparomlimab, an IgG4κ anti-human PD-1/CD279/PDCD1 antibody, additionally binds to the human monoclonal PSB103 γ4-chain, forming a dimer through disulfide linkage with the human monoclonal PSB103 κ-chain. It is utilized in oncology research [1].
价 格:¥电议型 号:T77040产 地:中国大陆
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T7704KY-226;化合物KY-226KY-226
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)
价 格:¥电议型 号:T7704产 地:中国大陆
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T77039Ipafricept;化合物 IpafriceptIpafricept
Ipafricept (OMP-54F28; FZD8-Fc), a pioneering recombinant fusion protein, incorporates the extracellular segment of the human frizzled-8 receptor and the Fc fragment of human IgG1, targeting the Wnt ligand. It exhibits activity in inhibiting solid tumors and is well tolerated [1].
价 格:¥电议型 号:T77039产 地:中国大陆
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T77038Interferon alfa;化合物 Interferon alfaInterferon alfa
Interferon alfa, a type I interferon, activates new genes, displaying strong antiviral and antiproliferative effects on target cells. It signals through receptor-mediated activation of Stat1 and Stat2, which heterodimerize into a STAT complex binding with the DNA-binding protein IRF-9 (p48) to form ISGF-3 (IFN-stimulated gene factor 3). This complex further activates driver genes to fulfill its antiviral role [1].
价 格:¥电议型 号:T77038产 地:中国大陆
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T77037Insulin efsitora alfa;化合物 Insulin efsitora alfaInsulin efsitora alfa
Insulin efsitora alfa (LY-3209590) is a selective insulin receptor (IR) agonist, comprising a fusion protein that integrates human IR agonists with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2), and has a molecular weight of 64.1 kDa. This compound is well tolerated and shows promise for use in diabetes management [1].
价 格:¥电议型 号:T77037产 地:中国大陆
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T77036Inolimomab;化合物 InolimomabInolimomab
Inolimomab, an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody, has demonstrated potential to enhance survival rates in preliminary studies addressing acute graft-versus-host disease (aGVHD) [1] [2].
价 格:¥电议型 号:T77036产 地:中国大陆
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T77035Inezetamab;化合物 InezetamabInezetamab
Inezetamab is a bispecific anti- CD40 and anti- MSLN IgG1 monoclonal antibody [1] .
价 格:¥电议型 号:T77035产 地:中国大陆
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T77034Inbakicept;化合物 InbakiceptN-803;N-803
Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity (ADCC). Inbakicept also increases degranulation, IFNγ production in cells [1] .
价 格:¥电议型 号:T77034产 地:中国大陆
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T77033Imvotamab;化合物 ImvotamabImvotamab
Imvotamab (IGM-2323), a CD20xCD3 bispecific IGM antibody featuring a dual-action mechanism, promotes physiological T cell activation to avoid both over-stimulation and immune function down-regulation. This compound is under development for addressing B-cell malignant tumors, including multiple myeloma (MM) and non-Hodgkin´s lymphoma (NHL) [1] [2] [3] [4].
价 格:¥电议型 号:T77033产 地:中国大陆
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T77032Imsidolimab;化合物 ImsidolimabImsidolimab
Imsidolimab (ANB 019), a high-affinity, humanized monoclonal antibody targeting IL-36R, antagonizes IL-36 cytokine signal transduction, showing potential in treating generalized pustular psoriasis (GPP) and other inflammatory skin diseases [1] [2].
价 格:¥电议型 号:T77032产 地:中国大陆
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T77031Ifabotuzumab;化合物 IfabotuzumabIfabotuzumab
Ifabotuzumab (KB004), an IgG1κ antibody, specifically binds to EphA3 (K D =610 pM), inducing tumor cell apoptosis, activating antibody-dependent cell-mediated cytotoxicity (ADCC), and damaging tumor vasculature. Additionally, Ifabotuzumab effectively reduces CCR10+ cells in human idiopathic pulmonary fibrosis (IPF) and ameliorates pulmonary fibrosis, demonstrating its therapeutic potential [1] [2].
价 格:¥电议型 号:T77031产 地:中国大陆
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T77030Gumokimab;化合物 GumokimabGumokimab
Gumokimab (AK 111), a monoclonal antibody, targets IL-17A and is utilized in researching psoriasis and ankylosing spondylitis. It competitively inhibits the interaction between human IL-17A and its receptor, IL-17R.
价 格:¥电议型 号:T77030产 地:中国大陆
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T77029Gremubamab;化合物 GremubamabGremubamab
Gremubamab (MEDI3902), a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody, specifically targets and binds to the Pseudomonas aeruginosa PcrV protein and Psl exopolysaccharide. It shows promise for the study of Pseudomonas aeruginosa infections [1] [2].
价 格:¥电议型 号:T77029产 地:中国大陆
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T77028Gosuranemab;化合物 GosuranemabGosuranemab
Gosuranemab (BMS-986168), a humanized IgG4 anti-tau monoclonal antibody, specifically targets human N-terminal tau residues 15-22. It holds potential for Alzheimer’s disease (AD) research [1] [2].
价 格:¥电议型 号:T77028产 地:中国大陆
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T77027Gontivimab;化合物 GontivimabGontivimab
Gontivimab (ALX-0171; VR-465), a potent anti-RSV prefusion F protein nanobody, exhibits antiviral activity by reducing the RSV load in the nose and lung, with a dissociation constant (K D) of 0.113 nM [1].
价 格:¥电议型 号:T77027产 地:中国大陆
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T77026Goflikicept;化合物 GoflikiceptGoflikicept
Goflikicept (RPH 104), a hybrid protein, selectively targets and neutralizes circulating IL-1? and IL-1α. This compound shows promise for the investigation of ST-segment elevation myocardial infarction (STEMI) [1].
价 格:¥电议型 号:T77026产 地:中国大陆
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T77025Gimsilumab;化合物 GimsilumabGimsilumab
Gimsilumab (MORAb-022), a humanized anti-GM-CSF monoclonal antibody, shows promise in the research of COVID-19 and rheumatoid arthritis (RA) [1] [2].
价 格:¥电议型 号:T77025产 地:中国大陆
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T77024Gilvetmab;化合物 GilvetmabGilvetmab
Gilvetmab, a potent caninized anti-PD-1 monoclonal antibody, effectively inhibits the interaction between PD-1 and its ligand PDL-1 [1].
价 格:¥电议型 号:T77024产 地:中国大陆