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T78142DC-BPi-11 hydrochloride；化合物 DC-BPi-11 hydrochlorideDC-BPi-11 hydrochloride
DC-BPi-11 hydrochloride is a BPTF (bromodomain PHD finger transcription factor) inhibitor with an IC50 value of 698 nM, demonstrating significant anti-proliferative effects on leukemia cells [1].
价 格：￥电议型 号：T78142产 地：中国大陆
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T77142Ranevetmab；化合物 RanevetmabRanevetmab
Ranevetmab (NV-01), a caninized anti-nerve growth factor (anti-NGF) monoclonal antibody (mAb), is utilized in research for alleviating pain associated with degenerative joint disease (DJD) in canines.
价 格：￥电议型 号：T77142产 地：中国大陆
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T76142Laccase；化合物 LaccaseLaccase
Laccase (Denilite IIS), a multi-copper oxidase (MCO), is prevalent in microorganisms, plants, and fungi. It catalyzes the oxidation of phenolic compounds by removing one electron and facilitates the oxidative coupling of lignin monomers. This process is vital for lignin formation and biodegradation, and laccase may also cross-link food polymers [1].
价 格：￥电议型 号：T76142产 地：中国大陆
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T75142Acid Ceramidase-IN-2；化合物 Acid Ceramidase-IN-2Acid Ceramidase-IN-2
Acid Ceramidase-IN-2 (compound 1), an acid ceramidase inhibitor, exhibits potentially antiproliferative and cytostatic effects. This compound is of interest due to the overexpression of human acid ceramidase in prostate cancer cells, suggesting its potential anti-tumor efficacy. Furthermore, the hydrolysis of Acid Ceramidase-IN-2 can be inhibited by 3 a-ketoamides: GT85, GT98, and GT99 in vitro [1].
价 格：￥电议型 号：T75142产 地：中国大陆
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T74820Antibacterial agent 142；化合物 Antibacterial agent 142Antibacterial agent 142
Antibacterial agent 142, an aromatic hydrazide, exhibits bacteriostatic antibacterial activity and inhibits biofilm formation [1].
价 格：￥电议型 号：T74820产 地：中国大陆
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T74142Angiotensin II human TFA；化合物 Angiotensin II human TFAAngiotensin II human TFA
Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). It not only prompts sympathetic nervous stimulation, aldosterone biosynthesis, and renal effects but also fosters growth in vascular smooth muscle cells and boosts collagen type I and III synthesis in fibrob
价 格：￥电议型 号：T74142产 地：中国大陆
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T73677SR 142948 dihydrochloride；化合物 SR 142948 dihydrochlorideSR 142948 dihydrochloride
SR 142948 dihydrochloride is a selective, orally active, non-peptide neurotensin receptor (NT) antagonist, featuring IC50 values of 1.19 nM, 0.32 nM, and 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. It effectively inhibits NT-induced inositol monophosphate formation in HT-29 cells (IC50 = 3.9 nM) and blocks NT-induced hypothermia, analgesia, and steering behavior in vivo. Furthermore, it demonstrates blood-brain barrier permeability, positioning it as a potential
价 格：￥电议型 号：T73677产 地：中国大陆
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T73142FLT3-IN-18；化合物 FLT3-IN-18FLT3-IN-18
FLT3-IN-18, a potent and selective FLT3 inhibitor, exhibits an IC50 value of 0.003 μM. It effectively induces apoptosis and G1 phase cell cycle arrest, while inhibiting FLT3 and STAT5 phosphorylation. This compound holds potential for acute myeloid leukemia (AML) research.
价 格：￥电议型 号：T73142产 地：中国大陆
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T72744(R)-PF-06256142；化合物 (R)-PF-06256142(R)-PF-06256142
(R)-PF-06256142, the R enantiomer of PF-06256142, exhibits low activity. PF-06256142 itself is distinguished as a potent and selective orthosteric D1 receptor agonist, with the capability to minimize receptor desensitization compared to dopamine and other catechol-containing agonists.
价 格：￥电议型 号：T72744产 地：中国大陆
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T72642Cefepime chloride；化合物 Cefepime chlorideBMY-28142 chloride；BMY-28142 chloride
Cefepime chloride (BMY-28142) is a broad-spectrum cephalosporin capable of crossing the blood-brain barrier, exhibiting antibacterial activity against both Gram-positive and Gram-negative aerobic bacteria. It also induces neurotoxicity.
价 格：￥电议型 号：T72642产 地：中国大陆
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T71429O-Demethyl apixaban sulfate；化合物 O-Demethyl apixaban sulfateO-Demethyl apixaban sulfate
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases.
价 格：￥电议型 号：T71429产 地：中国大陆
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T71428Mocoht bromide；化合物 Mocoht bromideMocoht bromide
Mocoht bromide is new antagonists of platelet activating factor.
价 格：￥电议型 号：T71428产 地：中国大陆
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T71427N-(5-((2-Methylene-3-(((octadecylamino)carbonyl)oxy)propoxy)carbonyl)pentyl)pyridinium；化合物 N-(5-((2-
N-(5-((2-Methylene-3-(((octadecylamino)carbonyl)oxy)propoxy)carbonyl)pentyl)pyridinium is a platelet activating factor antagonist.
价 格：￥电议型 号：T71427产 地：中国大陆
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T71426STA-1474；化合物 STA-1474STA-1474
STA-1474 is a water soluble prodrug of ganetespib (formerly STA-9090). STA-1474 will metabolized to Ganetespib, which is a potent HSP90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibit tumor growth in the setting of murine xenografts. The purpose of the following study was to extend these observations and investigate the safety and efficacy of STA-1474 in dogs with spontaneous tumors.
价 格：￥电议型 号：T71426产 地：中国大陆
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T71425Noberastine maleate；化合物 Noberastine maleateNoberastine maleate
Noberastine maleate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapid onset, and shorter duration of action than astemizole with peak antihistaminic activity at 4h following ingestion. Noberastine is rapidly absorbed and the peak plasma levels are obtained within 2 h of oral dosing. In preclinical studies Noberastine has been shown to lack centra
价 格：￥电议型 号：T71425产 地：中国大陆
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T71424VT-102 free base；化合物 VT-102 free baseVT-102 free base
VT-102 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT102 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect on the Renilla luciferase reporter.
价 格：￥电议型 号：T71424产 地：中国大陆
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T71423AZD5213；化合物 AZD-5213AZD5213
AZD5213 is a selective, competitive antagonist of the human H3 receptor, exhibiting a pK i of 9.3 against hH3R. It is utilized in the research of sleep and cognitive regulation.
价 格：￥电议型 号：T71423产 地：中国大陆
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T71422S6821；化合物 S6821S6821
S6821 is a TAS2R8 antagonist. S6821 was not found to be mutagenic or clastogenic in vitro, and did not induce micronuclei in bone marrow polychromatic erythrocytes in vivo.
价 格：￥电议型 号：T71422产 地：中国大陆
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T71421Bemoradan；化合物 BemoradanBemoradan
Bemoradan is an inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue
价 格：￥电议型 号：T71421产 地：中国大陆
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T71420RO314724；化合物 RO314724RO314724
RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage matrix during chronic rheumatic diseases. Ro314724 displayed MMP-proteoglycanase inhibitory activity both in vitro and ex vivo and proved to be not harmful to the morphology, viability and proteoglycan biosynthesis of bovine articular cartilage explants.
价 格：￥电议型 号：T71420产 地：中国大陆
