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T70235Cemadotin hydrochloride;化合物 Cemadotin hydrochlorideCemadotin hydrochloride
Cemadotin hydrochloride is the salt from of Cemadotin (free base), also known as, LU103793, a mitosis inhibitor potentially for the treatment of solid tumours. Cemadotin is also a synthetic derivative of Dolastatin 15, an antiproliferative compound which was isolated from the mollusk Dolabella auricularia. Like Dolastatin 15, LU103793 is highly cytotoxic in vitro (IC50 = 0.1 nM). LU103793 inhibits microtubule polymerization in a concentration-dependent manner (IC50 = 7 microM). Treatment with
价 格:¥电议型 号:T70235产 地:中国大陆
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T6S2356Corynoline;紫蓳灵(+)-Corynoline;紫蓳灵|||堇醇灵碱|||(+)-Corynoline
1. Corynoline ((+)-Corynoline) is an acetylcholinesterase inhibitor.
价 格:¥电议型 号:T6S2356产 地:中国大陆
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T69235TB-2-081;化合物 TB-2-081TB-2-081
TB-2-081 is a antagonist of IL-6 signaling.
价 格:¥电议型 号:T69235产 地:中国大陆
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T68235Beclabuvir HCl;化合物 Beclabuvir HClBeclabuvir HCl
Beclabuvir, also known as BMS-791325, is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. BMS-791325 inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 at 50% inhibitory concentrations (IC50) below 28 nM. In cell culture, BMS-791325 inhibited replication of HCV subgenomic replicons representing genotypes 1a and 1b at 50% effective concentrations (EC50s) of 3 nM and 6 nM, respectively, with similar (3 to 18 nM)
价 格:¥电议型 号:T68235产 地:中国大陆
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T67934MRT-2359;化合物MRT-2359MRT-2359
MRT-2359 is a potent and orally available GSPT1 reducer with antitumour activity.MRT-2359 inhibits the growth of drug-resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells.MRT-2359 exhibits preferential activity in MYC-driven cell lines.
价 格:¥电议型 号:T67934产 地:中国大陆
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T67235(S)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(diphenylphosphino)ethyl]ferrocene;化合物 (S)-1-[(S)-tert-Bu
(S)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(diphenylphosphino)ethyl]ferrocene is a useful organic compound for research related to life sciences and the catalog number is T67235.
价 格:¥电议型 号:T67235产 地:中国大陆
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T66235H-Ser(tBu)-OMe.HCl;化合物 H-Ser(tBu)-OMe.HClH-Ser(tBu)-OMe.HCl
H-Ser(tBu)-OMe.HCl is an amino acid derivative and has a wide range of applications in life science related research.
价 格:¥电议型 号:T66235产 地:中国大陆
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T65235Hexahydrohippuric acid;化合物 Hexahydrohippuric acidHexahydrohippuric acid
Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.
价 格:¥电议型 号:T65235产 地:中国大陆
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T64235Antifungal agent 25;化合物 Antifungal agent 25Antifungal agent 25
Antifungal agent 25 is an effective, broad-spectrum, metabolically stable antifungal agent in vivo. antifungal agent 25 exhibits antifungal effects against both Candida albicans and fluconazole-resistant Candida albicans.
价 格:¥电议型 号:T64235产 地:中国大陆
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T64108DX3-235;化合物 DX3-235DX3-235
DX3-235 is an inhibitor of oxidative phosphorylation (OXPHOS). In galactose-containing media, DX3-235 inhibits complex I function and ATP production by nanomolar amounts and is significantly cytotoxic.
价 格:¥电议型 号:T64108产 地:中国大陆
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T63235KRAS inhibitor-14;化合物 KRAS inhibitor-14KRAS inhibitor-14
KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers.
价 格:¥电议型 号:T63235产 地:中国大陆
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T6279LGivinostat hydrochloride;化合物Givinostat hydrochlorideITF2357 hydrochloride|||Givinostat HCl|||ITF2357
Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineoplastic activities.
价 格:¥电议型 号:T6279L产 地:中国大陆
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T6279Givinostat hydrochloride monohydrate;吉维司他ITF2357|||ITF-2357 hydrochloride monohydrate|||Givinostat||
Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.
价 格:¥电议型 号:T6279产 地:中国大陆
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T62359TLR4/NF-κB/MAPK-IN-1;化合物 TLR4/NF-κB/MAPK-IN-1TLR4/NF-κB/MAPK-IN-1
TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.
价 格:¥电议型 号:T62359产 地:中国大陆
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T62358BM635 hydrochloride;化合物 BM635 hydrochlorideBM635 hydrochloride
BM635 hydrochloride is an MmpL3 inhibitor that exhibits significant anti-Divergent bacteriophage effects, inhibiting the binding of Divergent bacteriophage H37Rv (MIC50: 0.08 μM). Exposure to BM635 hydrochloride was doubled in vivo compared to free BM635.
价 格:¥电议型 号:T62358产 地:中国大陆
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T62357ET-JQ1-OH;化合物 ET-JQ1-OHET-JQ1-OH
ET-JQ1-OH is an allele-specific BET inhibitor.
价 格:¥电议型 号:T62357产 地:中国大陆
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T62356Mardepodect hydrochloride;Mardepodect 盐酸盐PF-2545920 HCl|||Mardepodect HCl|||MP-10 HCl|||PF-02545920
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of proteins encoding specific growth and transcription factors, cell signalling molecules and cell surface proteins. Mardepodect hydrochloride upregulates genes encoding specific growth factors, transcription factors, cell signalling molecules, and cell surface proteins, while downregul
价 格:¥电议型 号:T62356产 地:中国大陆
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T62355HBV-IN-14;化合物 HBV-IN-14HBV-IN-14
HBV-IN-14 is a pyridinopyrimidinone compound and a potent covalent closed-loop DNA (cccDNA) inhibitor. HBV-IN-14 has potential for the study of HBV infection.
价 格:¥电议型 号:T62355产 地:中国大陆
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T62354CDK8-IN-7;化合物 CDK8-IN-7CDK8-IN-7
CDK8-IN-7 (compound 12) is a potent and selective inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 3.5 nM). CDK8-IN-7 has shown potential for AML-cancer research.
价 格:¥电议型 号:T62354产 地:中国大陆
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T62353HIV-1 inhibitor-33;化合物 HIV-1 inhibitor-33HIV-1 inhibitor-33
HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor that acts on HIV-1 (EC50: 8.6 nM), MT-4 cells (CC50: 18 μM). HIV-1 inhibitor-33 can be used in the study of AIDS.
价 格:¥电议型 号:T62353产 地:中国大陆