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T62352CXCR4 modulator-2;化合物 CXCR4 modulator-2CXCR4 modulator-2
CXCR4 modulator-2 (compound Z7R) is a potent modulator of CXCR4 (IC50: 1.25 nM). CXCR4 modulator-2 exhibits good stability in mouse serum (t1/2= 77.1 min) and has anti-inflammatory effects in a mouse oedema model.
价 格:¥电议型 号:T62352产 地:中国大陆
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T62351Lotrafiban;化合物 LotrafibanLotrafiban
Lotrafiban is an orally active platelet membrane glycoprotein IIb/IIIa blocker that can be used in the treatment of coronary heart disease and cerebrovascular disease.
价 格:¥电议型 号:T62351产 地:中国大陆
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T62350XO/COX/LOX-IN-1;化合物 XO/COX/LOX-IN-1XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 is a potent inhibitor of xanthine oxidase/cyclooxygenase/lipoxygenase XO/COX/LOX. XO/COX/LOX-IN-1 can be used in the study of inflammatory, cancer and metabolic diseases.
价 格:¥电议型 号:T62350产 地:中国大陆
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T6235Lapatinib Ditosylate;二甲苯磺酸拉帕替尼Lapatinib (GW-572016) Ditosylate|||GW-572016 ditosylate|||Tykerb ditos
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
价 格:¥电议型 号:T6235产 地:中国大陆
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T62235CDK-IN-9;化合物 CDK-IN-9CDK-IN-9
CDK-IN-9 (compound 24) is a potent inhibitor of CDK. CDK-IN-9 is also a molecular gel that induces interaction between CDK12 and DDB1 and is able to act on CDK2/E (IC50: 4 nM). CDK-IN-9 can be used to dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis.
价 格:¥电议型 号:T62235产 地:中国大陆
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T61235CXCR2 antagonist 5;化合物 CXCR2 antagonist 5CXCR2 antagonist 5
CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity ( IC 50 =0.013 μM) and calcium mobilization ( IC 50 =0.1 μM) [ 1].
价 格:¥电议型 号:T61235产 地:中国大陆
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T61095SCH-42354;化合物 SCH-42354SCH-42354
SCH-42354 is a potent, orally active inhibitor of neutral endopeptidase (NEP), serving as the active form of the prodrug SCH-42495. By inhibiting NEP hydrolysis, SCH-42354 enhances the activity of atrial natriuretic peptide (ANP) and prevents the hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. Furthermore, SCH-42354 exhibits antihypertensive activity [1] [2].
价 格:¥电议型 号:T61095产 地:中国大陆
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T6076EPZ015666化合物EPZ015666GSK3235025
EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.
价 格:¥电议型 号:T6076产 地:中国大陆
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T6061LMK-235;化合物LMK235LMK235;LMK235
LMK-235 is a potent HDAC inhibitor, and is used in cancer research.
价 格:¥电议型 号:T6061产 地:中国大陆
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T60235(Rac)-Lanicemine;化合物 (Rac)-Lanicemine(Rac)-Lanicemine
(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with Ki of 0.56-2.1 μM for NMDA receptor; IC 50 s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine shows antidepressant effects [1].
价 格:¥电议型 号:T60235产 地:中国大陆
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T5S2358Dehydrocorydaline;脱氢紫堇碱Dehydrocorydalin|||13-Methylpalmatine;Dehydrocorydalin|||脱氢紫堇碱|||13-Methylpal
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and ant
价 格:¥电议型 号:T5S2358产 地:中国大陆
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T5S2357Acetylcorynoline;乙酰紫堇灵(+)-Corynoline Acetate|||O-Acetylcorynoline;(+)-Corynoline Acetate|||O-Acetylc
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolo
价 格:¥电议型 号:T5S2357产 地:中国大陆
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T5S2350Beta-Acetoxyisovalerylshikonin;β-乙酰氧基异戊酰阿卡宁Acetoxyisovalerylalkannin;乙酰氧基异戊酰阿卡宁|||Acetoxyisovaleryla
Acetoxyisovalerylshikonin, a naphthoquinone derivative extracted from Arnebia euchroma, is a chemical compound.
价 格:¥电议型 号:T5S2350产 地:中国大陆
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T52355-Methoxy-DL-tryptophan;DL-5-甲氧基色氨酸5-Methoxy-DL-tryptophan
5-Methoxy-DL-tryptophan is a molecule produced by endothelial cells to modulate inflammatory responses and protect against systemic inflammation.
价 格:¥电议型 号:T5235产 地:中国大陆
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T4S2354Dimethylfraxetin;二甲基白蜡树亭Fraxetin dimethyl ether|||6,7,8-Trimethoxycoumarin;二甲基白蜡树亭|||Fraxetin dimeth
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
价 格:¥电议型 号:T4S2354产 地:中国大陆
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T4235Roblitinib;化合物RoblitinibFGF-401;FGF-401
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. Roblitinib is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival.
价 格:¥电议型 号:T4235产 地:中国大陆
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T413469-Demethyl FR-901235;化合物 9-Demethyl FR-9012359-Demethyl FR-901235
9-Demethyl FR-901235 is a demethyl form of FR-901235, which is an immunoactive substance.
价 格:¥电议型 号:T41346产 地:中国大陆
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T41235γ-Linolenic acid ethyl ester;化合物 γ-Linolenic acid ethyl esterγ-Linolenic acid ethyl ester
γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B 4 receptor 4 (LTB 4 ) antagonist which has a potential anti-inflammatory effect[1].
价 格:¥电议型 号:T41235产 地:中国大陆
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T4078SB 242235化合物SB242235SB-242235|||SB242235
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.
价 格:¥电议型 号:T4078产 地:中国大陆
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T40235Kbz probe 1;Kbz probe 1Kbz probe 1
Kbz probe 1, an adaptable probe utilized for examining histone benzoylation and interactions within living cells, showcases extensive versatility.
价 格:¥电议型 号:T40235产 地:中国大陆