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T62711OPC-14523 hydrochloride;OPC-14523 盐酸盐VPI 013 hydrochloride;VPI 013 hydrochloride
OPC-14523 hydrochloride (VPI 013 hydrochloride) is an orally active and potent sigma and 5-HT1A receptor agonist with antidepressant activity for the study of neurological disorders.
价 格:¥电议型 号:T62711产 地:中国大陆
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T62710Antitrypanosomal agent 6;化合物 Antitrypanosomal agent 6Antitrypanosomal agent 6
Antitrypanosomal agent 6 (compound 18a) is a potent antitrypanosomal agent showing good ADME properties. Antitrypanosomal agent 6 is more than twice as active as Nifurtimox against Trypanosoma brucei (T. brucei) with an IC50 of 0.47 μM. Antitrypanosomal agent 6 has a strong interaction with DNA and selectively binds AT-rich DNA.
价 格:¥电议型 号:T62710产 地:中国大陆
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T6271Tipifarnib;替吡法尼R115777|||Zarnestra|||IND 58359;替吡法尼|||R115777|||Zarnestra|||IND 58359
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.
价 格:¥电议型 号:T6271产 地:中国大陆
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T62271HER2-IN-9;化合物 HER2-IN-9HER2-IN-9
HER2-IN-9 is an orally active HER2 inhibitor (IC50: 0.03 μM). HER2-IN-9 inhibits the proliferation and migration of HER-2-positive breast cancer cells and can be used in breast cancer research.
价 格:¥电议型 号:T62271产 地:中国大陆
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T6177PF-562271 besylate;化合物PF-562271 besylatePF-00562271 Besylate;PF-00562271 Besylate
PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
价 格:¥电议型 号:T6177产 地:中国大陆
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T61725VU0463271 quarterhydrate;化合物 VU0463271 quarterhydrateVU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].
价 格:¥电议型 号:T61725产 地:中国大陆
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T60271SARS-CoV-2 nsp3-IN-2;化合物 SARS-CoV-2 nsp3-IN-2SARS-CoV-2 nsp3-IN-2
SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with IC 50 value of 180 μM. SARS-CoV-2 nsp3 macrodomain is an ADP-ribosylhydrolase that is critical for coronavirus replication and pathogenesis. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe that can be used for the viral research[1].
价 格:¥电议型 号:T60271产 地:中国大陆
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T6007Birinapant比瑞那帕TL32711|||比瑞那帕
Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
价 格:¥电议型 号:T6007产 地:中国大陆
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T4511ST271;化合物ST 271ST 271;ST 271
ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
价 格:¥电议型 号:T4511产 地:中国大陆
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T4307PF-06840003;化合物PF06840003EOS200271|||PF 06840003;EOS200271|||PF 06840003
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.
价 格:¥电议型 号:T4307产 地:中国大陆
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T4271Diroximel fumarate;化合物Diroximel FumareteDiroximel Fumarete;Diroximel Fumarete
Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.
价 格:¥电议型 号:T4271产 地:中国大陆
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T4261BPR1J-097 hydrochloride (1327167-19-0(free base));化合物BPR1J-097 hydrochlorideBPR1J-097 hydrochloride
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
价 格:¥电议型 号:T4261产 地:中国大陆
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T41271PHOME;化合物 PHOMEPHOME
PHOME has a wide range of applications in life science related research.
价 格:¥电议型 号:T41271产 地:中国大陆
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T4118SB 271046 hydrochloride;化合物SB 271046 hydrochlorideSB 271046A;SB 271046A
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant act
价 格:¥电议型 号:T4118产 地:中国大陆
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T4040AN2718;化合物AN2718AN2718
AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.
价 格:¥电议型 号:T4040产 地:中国大陆
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T40271MrgprX2 antagonist-3MrgprX2 antagonist-3MrgprX2 antagonist-3
MrgprX2 antagonist-3 is a potent inhibitor of MrgprX2. It holds promising potential for investigating skin inflammatory disorders.
价 格:¥电议型 号:T40271产 地:中国大陆
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T39271MLT-985;MLT-985MLT-985
MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC 50 value of 3 nM.
价 格:¥电议型 号:T39271产 地:中国大陆
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T39067MAGE-3 (271-279);MAGE-3 (271-279)MAGE-3 (271-279)
MAGE-3 (271-279) is a peptide consisting of 271-279 amino acid residues that is derived from melanoma antigens encoded by the MAGE-3 gene. It is specifically recognized by cytolytic T lymphocytes (CTLs) and binds to the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is highly expressed in various human tumor types, such as malignant melanoma, but not in normal tissues, except for the testis and placenta.
价 格:¥电议型 号:T39067产 地:中国大陆
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T38271TH1217;化合物TH1217TH 1217;TH 1217
TH1217, a potent and selective inhibitor of dCTPase pyrophosphatase 1 (dCTPase), demonstrates an IC50 value of 47 nM. It amplifies the cytotoxic impact of cytidine analogues on leukemia cells and exhibits potential against COVID-19 by modulating SARS-CoV-2 interactors.
价 格:¥电议型 号:T38271产 地:中国大陆
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T372719(E)-Erythromycin A oxime;9(E)-Erythromycin A oxime9(E)-Erythromycin A oxime
(9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin .
价 格:¥电议型 号:T37271产 地:中国大陆