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T83541(Gln22,Asn23)-Amyloid β-Protein (1-40);化合物 (Gln22,Asn23)-Amyloid β-Protein (1-40)(Gln22,Asn23)-Amylo
(Gln22,Asn23)-Amyloid β-Protein (1-40) is a peptide employed in the study of Cerebral Amyloid Angiopathy Mutations [1].
价 格:¥电议型 号:T83541产 地:中国大陆
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T83507[Asn23] β-Amyloid (1-40), Iowa mutation;化合物 [Asn23] β-Amyloid (1-40), Iowa mutation[Asn23] β-Amyloid
[Asn23] β-Amyloid (1-40), Iowa mutation, is a biologically active peptide associated with autosomal dominant Alzheimer´s Disease in multiple families. This specific mutation involves the substitution of Asp 23 with Asn, leading to severe cerebral amyloid beta-protein angiopathy (CAA). Individuals with this mutation exhibit a missense alteration in the APP gene at position 694, which results in the mutated β-amyloid peptide aggregating more quickly and forming toxic fibrils.
价 格:¥电议型 号:T83507产 地:中国大陆
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T83506[Asn23]-beta-Amyloid (1-42), iowa mutation;化合物 [Asn23]-beta-Amyloid (1-42), iowa mutation[Asn23]-bet
[Asn23]-beta-Amyloid (1-42), Iowa mutation, is a biologically active peptide exhibiting increased aggregation propensity and fibril toxicity. This mutation involves the substitution of Aspartic acid (Asp) at position 23 with Asparagine (Asn), contributing to autosomal dominant Alzheimer´s Disease in various kindreds due to its association with severe cerebral amyloid beta-protein angiopathy (CAA). Specifically, the mutation is a missense alteration at position 694 of the amyloid precursor
价 格:¥电议型 号:T83506产 地:中国大陆
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T834761,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine;化合物 1,2-Diheptadecanoyl-sn-glycero-3-phosphorylch
1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine (DHPC) is a derivative of phosphatidylcholine (PC) that exhibits biological activity, functioning as a phospholipid compound [1].
价 格:¥电议型 号:T83476产 地:中国大陆
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T834231-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine;化合物 1-Palmitoyl-2-[3-(dipheny
1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine, featuring a phosphatidylethanolamine head group, serves as a fluorescent probe to assess surface lipid oxidation in lipoproteins and plasma [1].
价 格:¥电议型 号:T83423产 地:中国大陆
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T834221-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine;化合物 1-Palmitoyl-2-succinyl-sn-glycerophosphorylch
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine, a glycerophosphorylcholine derivative, comprises glycerol phosphate, choline, and palmitic acid and accumulates at oxidative stress sites in vivo. It potentially acts as a ligand for scavenger receptors class B, akin to oxidized phospholipids oxPC(CD36), which are established potent ligands for receptors CD36 and SR-BI. These oxidized phospholipids also play a pivotal role in promoting tumor apoptosis and may present in higher concentrations wi
价 格:¥电议型 号:T83422产 地:中国大陆
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T834211-Palmitoyl-sn-glycerol 3-phosphate;化合物 1-Palmitoyl-sn-glycerol 3-phosphate1-P-GPA;1-P-GPA
1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA), an endogenous metabolite, is utilized in the research of non-alcoholic fatty liver disease [1].
价 格:¥电议型 号:T83421产 地:中国大陆
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T83205Ac-DNLD-CHO;化合物 Ac-DNLD-CHOAc-Asp-Asn-Leu-Asp-CHO;Ac-Asp-Asn-Leu-Asp-CHO
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7 nM, respectively. This compound is utilized in the study of diseases associated with caspase-mediated apoptosis, including neurodegenerative and viral infection diseases [1].
价 格:¥电议型 号:T83205产 地:中国大陆
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T82957ASN 07115873;化合物 ASN 07115873ASN 07115873
ASN 07115873 is an anti-Zika virus (ZIKV) compound with an inhibitory concentration (IC50) of 189.2 picomolar (pM), suitable for antiviral research [1].
价 格:¥电议型 号:T82957产 地:中国大陆
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T82946Atisnolerbart;化合物 AtisnolerbartAtisnolerbart
Atisnolerbart, a human IgG4 antibody, specifically targets BETVIA, which is identified as the major birch pollen allergen, Bet v 1-A.
价 格:¥电议型 号:T82946产 地:中国大陆
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T82895Berlimatoxumab;化合物 BerlimatoxumabASN-2;ASN-2
Berlimatoxumab (ASN-2) is an antibody utilized for experimental research.
价 格:¥电议型 号:T82895产 地:中国大陆
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T82727Chromoionophore XIII;化合物 Chromoionophore XIIISNARF-DE;SNARF-DE
Chromoionophore XIII (SNARF-DE), functioning as a pH sensor, is excitable with red light. Its unique properties impart lipophilicity and prevent the lactonization of the dye in apolar environments, ensuring the molecule´s water insolubility [1].
价 格:¥电议型 号:T82727产 地:中国大陆
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T82710CL2E-SN38;化合物 CL2E-SN38CL2E-SN38
CL2E-SN-38 is a structurally stable and highly releasable antibody-drug conjugate (ADC) incorporating SN-38, the active metabolite of Irinotecan and a potent Topoisomerase I inhibitor [1] from the camptothecins class.
价 格:¥电议型 号:T82710产 地:中国大陆
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T82429Euphoheliosnoid A;化合物 Euphoheliosnoid AEuphoheliosnoid A
Euphoheliosnoid A (Compound 24), a diterpenoid, significantly enhances natural killer (NK) cell-mediated cytotoxicity against H1299-luci cells and A549-luci cells at a concentration of 2.5 μM [1].
价 格:¥电议型 号:T82429产 地:中国大陆
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T82260Grisnilimab;化合物 GrisnilimabWT1;WT1
"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms´ tumor. It modulates the transcription of various genes and may be involved in post-transcriptional RNA processing [1]."
价 格:¥电议型 号:T82260产 地:中国大陆
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T82259Grisnilimab setaritox;化合物 Grisnilimab setaritoxWT1-RTA;WT1-RTA
Grisnilimab setaritox (WT1-RTA), an anti-CD7 antihuman T cell antibody linked to ricin A chain (RTA), exhibits in vitro cytotoxicity against CEM (T-lymphoblastic leukemia) cells with an ID 50 of 53 pM. The 30-kDa RTA component disrupts the function of 60S ribosomal subunits. Additionally, Grisnilimab setaritox has demonstrated efficacy in ameliorating leukemic meningitis in a rhesus monkey model [1].
价 格:¥电议型 号:T82259产 地:中国大陆
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T82011JBSNF-000028 free base;化合物 JBSNF-000028 free baseJBSNF-000028 free base
JBSNF-000028 is an orally active inhibitor of nicotinamide N-methyltransferase (NNMT) demonstrating inhibitory concentration (IC50) values of 0.033 ?M for human NNMT (hNNMT), 0.19 ?M for monkey NNMT (mkNNMT), and 0.21 ?M for mouse NNMT (mNNMT). This compound may be utilized in the study of metabolic disorders [1].
价 格:¥电议型 号:T82011产 地:中国大陆
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T8198Visnagin;齿阿米素Visnagin
Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.
价 格:¥电议型 号:T8198产 地:中国大陆
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T81895Lysophosphatidylcholine C19:0;化合物 Lysophosphatidylcholine C19:01-Nonadecanoyl-2-hydroxy-sn-glycero-3
Lysophosphatidylcholine C19:0 (1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine), an acyl chain lipid, enhances IL-1beta secretion [1].
价 格:¥电议型 号:T81895产 地:中国大陆
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T81745MSN8C;化合物 MSN8CMSN8C
MSN8C, a mansonone E analog, acts as a novel catalytic inhibitor of human DNA topoisomerase II, inducing apoptosis in cancer cells and exhibiting considerable anti-tumor cell proliferation activity in vitro [1].
价 格:¥电议型 号:T81745产 地:中国大陆