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T6071ParbendazoleSKF 29044;帕苯咪唑
Parbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
价 格:¥电议型 号:T6071产 地:中国大陆
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T6070ON-01910N-[2-甲氧基-5-[[[2-(2,4,6-三甲氧基苯基)乙烯基]磺酰]甲基]苯基]甘氨酸钠盐
ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induce
价 格:¥电议型 号:T6070产 地:中国大陆
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T6069Gemcitabine hydrochlorideLY 188011 hydrochloride;LY188011;Gemzar;Gemcitabine HCl;吉西他滨盐酸盐;盐酸吉西他滨
Gemcitabine is a DNA synthesis inhibitor (IC50s: 12, 18, 40, 92.7, 89.3 in Capan2, BxPC-3, Mia Paca-2, PANC-1, and PL-45 cells, respectively).
价 格:¥电议型 号:T6069产 地:中国大陆
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T6067PD 123319(S)-(+)-PD 123319;PD123319
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist.
价 格:¥电议型 号:T6067产 地:中国大陆
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T6066SCH772984
SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.
价 格:¥电议型 号:T6066产 地:中国大陆
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T6065Triciribine曲西立滨;API-2;TCN;NSC 154020;VD-0002;Tricyclic nucleoside
Triciribine is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.
价 格:¥电议型 号:T6065产 地:中国大陆
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T6063LY-411575LY411575
LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.
价 格:¥电议型 号:T6063产 地:中国大陆
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T6062Brefeldin AAscotoxin;Cyanein;BFA;Decumbin;布雷非德菌素 A
Brefeldin A , a Penicillium brefeldianum metabolite, which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. It is also an ATPase inhibitor for protein transport in HCT 116 cells(IC50=0.2 μM), inducing Y cell differentiation and apo
价 格:¥电议型 号:T6062产 地:中国大陆
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T6061LMK-235LMK235;LMK 235
LMK-235 is a potent HDAC inhibitor, and is used in cancer research.
价 格:¥电议型 号:T6061产 地:中国大陆
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T6059GSK343
GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against other histone methyltransferases.
价 格:¥电议型 号:T6059产 地:中国大陆
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T6058LY2886721
LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer´s Disease.
价 格:¥电议型 号:T6058产 地:中国大陆
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T6057URMC-099URMC 099;URMC099
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
价 格:¥电议型 号:T6057产 地:中国大陆
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T6056Thiamet G
Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal –hexosaminidase.
价 格:¥电议型 号:T6056产 地:中国大陆
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T6054GSK256066
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
价 格:¥电议型 号:T6054产 地:中国大陆
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T6053Turofexorate Isopropyl妥芬异丙酯;FXR-450;XL335;WAY-362450
Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
价 格:¥电议型 号:T6053产 地:中国大陆
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T6052GW 441756
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.
价 格:¥电议型 号:T6052产 地:中国大陆
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T6050TAK-700(S/R)-Orteronel;Orteronel
TAK-700 (Orteronel) is a potent and highly selective human 17, 20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.
价 格:¥电议型 号:T6050产 地:中国大陆
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T6049SNS-032SNS 032;BMS-387032;SNS032
SNS-032 is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM/4 nM), and no effect on CDK6.
价 格:¥电议型 号:T6049产 地:中国大陆
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T6048DalcetrapibJTT-705;RO4607381;达塞曲匹
Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
价 格:¥电议型 号:T6048产 地:中国大陆