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  • T6301Tosedostat托舍多特;CHR-2797

    CHR-2797 is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. CHR-2797 is converted intracellularly into a poorly membrane-permeable active metabolite (CHR-79888) which inhibits the M1 family of a

    价 格:¥电议型 号:T6301产 地:中国大陆

  • T6300DegrasynWP1130

    Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).

    价 格:¥电议型 号:T6300产 地:中国大陆

  • T6299GDC-0152GDC0152;GDC 0152

    GDC-0152 is a potent inhibitor of IAPs.

    价 格:¥电议型 号:T6299产 地:中国大陆

  • T6297Alvespimycin hydrochlorideAlvespimycin (17-DMAG) HCl;NSC 707545;17-DMAG hydrochloride;KOS-1022;BMS 8

    17-DMAG is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.

    价 格:¥电议型 号:T6297产 地:中国大陆

  • T6296RAF265CHIR-265

    RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.

    价 格:¥电议型 号:T6296产 地:中国大陆

  • T6295Dabigatran达比加群;BIBR 953;BIBR 953ZW

    Dabigatran is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.

    价 格:¥电议型 号:T6295产 地:中国大陆

  • T6294NVP-BSK805 2HCl (1092499-93-8(free base))BSK 805

    NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.

    价 格:¥电议型 号:T6294产 地:中国大陆

  • T6293Mycophenolate MofetilTM-MMF;RS 61443;吗替麦考酚酯

    Mycophenolate mofetil, an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).

    价 格:¥电议型 号:T6293产 地:中国大陆

  • T6291WZ4003

    WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases.

    价 格:¥电议型 号:T6291产 地:中国大陆

  • T6290TanespimycinKOS 953;17-AAG;CP 127374;NSC 330507;坦螺旋霉素

    Tanespimycin (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).

    价 格:¥电议型 号:T6290产 地:中国大陆

  • T6289DovitinibCHIR-258;TKI258;多韦替尼;度维替尼

    Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER

    价 格:¥电议型 号:T6289产 地:中国大陆

  • T6287TariquidarXR9576;他立喹达

    Tariquidar(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines.

    价 格:¥电议型 号:T6287产 地:中国大陆

  • T6285GSK-690693GSK690693

    GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.

    价 格:¥电议型 号:T6285产 地:中国大陆

  • T6284OnalespibAT13387;Onalespib (AT13387)

    Onalespib is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation

    价 格:¥电议型 号:T6284产 地:中国大陆

  • T6283Wortmannin渥曼青霉素;KY-12420;SL-2052

    Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM, with little selectivity within the PI3K family. Also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM.

    价 格:¥电议型 号:T6283产 地:中国大陆

  • T6282GSK461364GSK461364A

    GSK461364(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.

    价 格:¥电议型 号:T6282产 地:中国大陆

  • T6281TW-37TW37;TW 37

    TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).

    价 格:¥电议型 号:T6281产 地:中国大陆

  • T6280EnzastaurinLY317615;恩扎妥林

    Enzastaurin (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.

    价 格:¥电议型 号:T6280产 地:中国大陆

  • T6279LGivinostat hydrochlorideITF 2357;Givinostat HCl. gavinostat,;Givinostat HCl;ITF2357 HCl;ITF2357 hydr

    Givinostat hydrochloride is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineoplastic activities.

    价 格:¥电议型 号:T6279L产 地:中国大陆

  • T6279Givinostat hydrochloride monohydrate吉维司他;Givinostat;ITF-2357 hydrochloride monohydrate;ITF2357;Gavin

    Givinostat hydrochloride monohydrate is an HDAC inhibitor.

    价 格:¥电议型 号:T6279产 地:中国大陆

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