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  • T6258ZibotentanZD4054

    Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.

    价 格:¥电议型 号:T6258产 地:中国大陆

  • T6257AZ191

    AZ191(IC50 of 17 nM) is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.

    价 格:¥电议型 号:T6257产 地:中国大陆

  • T6256YYA-021YYA 021;YYA021

    YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.

    价 格:¥电议型 号:T6256产 地:中国大陆

  • T6255Bromosporine

    Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.

    价 格:¥电议型 号:T6255产 地:中国大陆

  • T6254IdasanutlinRo 5503781;RG7388;依达奴林

    Idasanutlin (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).

    价 格:¥电议型 号:T6254产 地:中国大陆

  • T6253Talazoparib他拉唑帕利;BMN-673;LT-673

    Talazoparib is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).

    价 格:¥电议型 号:T6253产 地:中国大陆

  • T6252Ipatasertib帕他色替;RG7440;GDC-0068

    Ipatasertib (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.

    价 格:¥电议型 号:T6252产 地:中国大陆

  • T6251PF-04691502PF4691502;PF 04691502

    PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.

    价 格:¥电议型 号:T6251产 地:中国大陆

  • T6250H-89 dihydrochlorideH 89 2HCl;5-Isoquinolinesulfonamide;Protein kinase inhibitor H-89 dihydrochlorid

    H 89 is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).

    价 格:¥电议型 号:T6250产 地:中国大陆

  • T6249AvagacestatBMS-708163

    Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.

    价 格:¥电议型 号:T6249产 地:中国大陆

  • T6248XL888

    XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis. Through this action, specific clie

    价 格:¥电议型 号:T6248产 地:中国大陆

  • T6247OnvansertibNMS-P937;NMS-1286937

    NMS-P937 (NMS1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.

    价 格:¥电议型 号:T6247产 地:中国大陆

  • T6245BAPTA-AMBAPTA/AM

    BAPTA-AM is a selective, permeable free calcium chelator.

    价 格:¥电议型 号:T6245产 地:中国大陆

  • T6243U-73122U73122

    U73122, an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.

    价 格:¥电议型 号:T6243产 地:中国大陆

  • T6242Rupatadine FumarateRinialer;Alergoliber;Rupafin;富马酸卢帕他定

    Rupatadine Fumarate (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.

    价 格:¥电议型 号:T6242产 地:中国大陆

  • T6241Quetiapine hemifumarate富马酸喹硫平;ICI-204636;Quetiapine Fumarate

    Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.

    价 格:¥电议型 号:T6241产 地:中国大陆

  • T6238WZ4002

    WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.

    价 格:¥电议型 号:T6238产 地:中国大陆

  • T6237TrelagliptinSYR-472;曲格列汀

    Trelagliptin is a highly specific and long-acting DPP-4 inhibitor.

    价 格:¥电议型 号:T6237产 地:中国大陆

  • T6236OzagrelOKY-046;Domenan;奥扎格雷

    Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.

    价 格:¥电议型 号:T6236产 地:中国大陆

  • T6235Lapatinib DitosylateTykerb ditosylate;GW-572016 ditosylate;Lapatinib (GW-572016) Ditosylate;二甲苯磺酸拉帕替

    Lapatinib is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).

    价 格:¥电议型 号:T6235产 地:中国大陆

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