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产品数:86101
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T8976PD-089828EGFR,ATP,nonselective,PD 089828,PDGFR,autophosphorylation,PD089828,HER1,Epidermal growth fa
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
价 格:¥电议型 号:T8976产 地:中国大陆
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T9950ElteN378ElteN378
ElteN378 is a highly potent synthetic inhibitor of FKBP12 with Ki of 0.5 nM, a low atomic weight ligand with affinity comparable to that of the macrolide Rapamycin.
价 格:¥电议型 号:T9950产 地:中国大陆
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TN13428-Epidiosbulbin E acetate8Epidiosbulbin E acetate,8-Epidiosbulbin E,Inhibitor,Bacterial,inhibit,8 Ep
8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.
价 格:¥电议型 号:TN1342产 地:中国大陆
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T9955EX-A5758EX A5758,EXA5758
EX-A5758 is a novel putative small molecule nNOS-NOS1AP inhibitor, suppressing inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability.
价 格:¥电议型 号:T9955产 地:中国大陆
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TQ0121VH-298E3 ligase-recruiting Moiety,VH-298,Inhibitor,VH298,Ligands for E3 Ligase,VH 298,inhibit
VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by PHD enzymes.
价 格:¥电议型 号:TQ0121产 地:中国大陆
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T25399ETP-45658ETP 45658;ETP45658
ETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).
价 格:¥电议型 号:T25399产 地:中国大陆
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T2086ELN-441958ELN 441958
ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958 is highly selective for B1 over B2 receptors.
价 格:¥电议型 号:T2086产 地:中国大陆
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T1788EPZ6438EPZ6438,E-7438,Tazemetostat
Tazemetostat is an orally available, small molecule selective and S-adenosyl methionine (SAM) competitive inhibitor of histone methyltransferase EZH2, with potential antineoplastic activity. Upon oral administration, Tazemetostat selectively inhibits the
价 格:¥电议型 号:T1788产 地:美洲
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T1908913-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide13-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide,Ethyl 4-(
13-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide is a derivative of Retinoic acid.
价 格:¥电议型 号:T19089产 地:美洲
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T4659ELN484228ELN484228
ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.
价 格:¥电议型 号:T4659产 地:美洲
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T83935eIF4A i28;化合物 eIF4A i28eIF4A i28
eIF4A i28, an inhibitor of the eukaryotic initiation factor-4A (eIF4A) with an IC50 of 8.60 μM in an eIF4A ATPase assay, effectively reduces the viability of BJAB Burkitt lymphoma cells, as indicated by an EC50 of 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. This compound functions as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor.
价 格:¥电议型 号:T83935产 地:中国大陆
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T79876EDI048;化合物 EDI048EDI048
EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized in the study of cryptosporidiosis [1].
价 格:¥电议型 号:T79876产 地:中国大陆
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T79694EGFR-IN-88;化合物 EGFR-IN-88EGFR-IN-88
EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis [1].
价 格:¥电议型 号:T79694产 地:中国大陆
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T79109Estrogen receptor modulator 8;化合物 Estrogen receptor modulator 8Estrogen receptor modulator 8
Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0.1 nM) [1].
价 格:¥电议型 号:T79109产 地:中国大陆
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T78940EGFR-IN-78;化合物 EGFR-IN-78EGFR-IN-78
EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, serves as a reversible EGFR C797S-TK inhibitor and an apoptosis inducer. It exhibits anti-proliferative properties, impedes EGFR phosphorylation, and induces G2/M phase cell cycle arrest [1].
价 格:¥电议型 号:T78940产 地:中国大陆
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T78646Estrogen receptor antagonist 8;Estrogen receptor 拮抗剂 8Estrogen receptor antagonist 8
Estrogen receptor antagonist 8 acts as an estrogen receptor (ER) antagonist with anti-uterine activity and potential anti-tumorigenic activity and can be used to study ovarian dysfunction.
价 格:¥电议型 号:T78646产 地:中国大陆
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T7758Thalidomide-O-amido-PEG3-C2-NH2 TFA;化合物T7758E3 ligase Ligand-Linker Conjugates 14 TFA|||Cereblon Lig
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T7758产 地:中国大陆
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T755071-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone;化合物 1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone1-M
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone exhibits strong antibacterial properties, demonstrating an MIC 50 of 22 ?M and an MIC 90 of 50 ?M against Helicobacter pylori Strain 51. This compound shows promise for research into gastric and duodenal ulcers [1].
价 格:¥电议型 号:T75507产 地:中国大陆
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T73920Ep300/CREBBP-IN-8;化合物 Ep300/CREBBP-IN-8Ep300/CREBBP-IN-8
Ep300/CREBBP-IN-8 (Example 37), a potent and orally active inhibitor of both Ep300 and CREBBP, exhibits IC50 values of 0.014 μM and 0.018 μM, respectively. This compound is utilized in cancer research [1].
价 格:¥电议型 号:T73920产 地:中国大陆