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T8409SYN1143c-Met/HGFR,SYN-1143,tumor,RON,dual,inhibit,SYN1143,SYN 1143,cancer,Inhibitor,c-Met
AMG-1 is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
价 格:¥电议型 号:T8409产 地:中国大陆
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TP1114LLeucokinin VIII acetateLeucokinin VIII acetate
Leucokinin VIII acetate is an diuretic octapeptide isolated form head extracts of the cockroach.
价 格:¥电议型 号:TP1114L产 地:中国大陆
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TN1140Onjisaponin BAutophagy,Onjisaponin B,Inhibitor,inhibit
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.
价 格:¥电议型 号:TN1140产 地:中国大陆
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TN4114Gardenin AGardenin A
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
价 格:¥电议型 号:TN4114产 地:中国大陆
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T6S1141Ganoderic acid AInhibitor,Autophagy,Ganoderic acid A,Apoptosis,inhibit,Endogenous Metabolite
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly su
价 格:¥电议型 号:T6S1141产 地:中国大陆
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TN11468-?Prenylnaringenininhibit,Apoptosis,8?Prenylnaringenin,8-?Prenylnaringenin,Inhibitor,8 ?Prenylnarin
8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,
价 格:¥电议型 号:TN1146产 地:中国大陆
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T16831(S)-SNAP5114(S)SNAP5114,(S)-SNAP-5114,(S) SNAP5114
(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.
价 格:¥电议型 号:T16831产 地:中国大陆
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T61148Flutrimazole
Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component.
价 格:¥电议型 号:T61148产 地:中国大陆
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TN11428-Oxocoptisine8-Oxocoptisine,inhibit,Inhibitor,8 Oxocoptisine,8Oxocoptisine
8-Oxycoptisine is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer
价 格:¥电议型 号:TN1142产 地:中国大陆
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TP1991LM 1145 acetateM 1145 acetate
M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 acetate has an additive effect on the signal transduction of galanin[1].
价 格:¥电议型 号:TP1991L产 地:中国大陆
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T7424NDI-091143NDI 091143,ACLY,inhibit,ATP Citrate Lyase,NDI-091143,NDI091143,Inhibitor
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
价 格:¥电议型 号:T7424产 地:中国大陆
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TP1238LACTH 1-14 acetate(25696-21-3 free base)ACTH 1 14 acetate(25696 21 3 free base),ACTH 114 acetate(2569
ACTH (1-14) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress.
价 格:¥电议型 号:TP1238L产 地:中国大陆
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T29114VRT-532
VRT-532 is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag) in cystic fibrosis, and modification of CFTR by small molecule modulator VRT-532 can increase ARSB and reduce the accumulation of 4-chondroitin sulfate.
价 格:¥电议型 号:T29114产 地:中国大陆
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TP1120LIRBP acetate(211426-18-5 free base)IRBP acetate(211426185 free base),IRBP acetate(211426 18 5 free b
IRBP(Interphotoreceptor Retinoid Binding Protein Fragment ) acetate is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uveitis (EAU).
价 格:¥电议型 号:TP1120L产 地:中国大陆
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T11149Ecopladib
Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.
价 格:¥电议型 号:T11149产 地:中国大陆
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T9021Ro0711401Ro0711401,Metabotropic glutamate receptors,mGluR,oral,PAM,Inhibitor,mGlu1,inhibit
Ro0711401 is an agonist of mGlu1 receptor.
价 格:¥电议型 号:T9021产 地:中国大陆
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TN11496’’-O-acetylsaikosaponin A6’’ O acetylsaikosaponin A,Inhibitor,acetyl,saikosaponin,osteoclast,6’’Oac
6´´-O-acetylsaikosaponin A is an acetyl saikosaponin isolated from the roots of Bupleurum chinense. Itshows some osteoclast-inhibiting activities
价 格:¥电议型 号:TN1149产 地:中国大陆
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T21142Bupirimate
Bupirimate, an active ingredient in plant protection products, is commonly used as a systemic fungicide and finds applications in controlling powdery mildew in roses, apple plantations. It belongs to the family of pyrimidines.
价 格:¥电议型 号:T21142产 地:中国大陆
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TP1896L1Kisspeptin 234 acetate(1145998-81-7 free base)Kisspeptin 234 acetate(1145998 81 7 free base),Kisspep
kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC50 = 7 nM) and release of gonadotrophin-releasing hormone (GnRH).
价 格:¥电议型 号:TP1896L1产 地:中国大陆
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TQ0094JNJ-40411813ADX71149,JNJ-40411813,ADX 71149,JNJ40411813,mGluR,Inhibitor,JNJ 40411813,Metabotropic gl
JNJ-40411813 (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).
价 格:¥电议型 号:TQ0094产 地:中国大陆