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T11465GS-6207GS-6207
GS-6207 displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs). GS-6207 is a HIV-1 capsid inhibitor. GS-6207 shows anti-HIV activity with an EC50 of 100 pM in MT-4
价 格:¥电议型 号:T11465产 地:美洲
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T11468GSK-3 inhibitor 1GSK-3 inhibitor 1
GSK-3 inhibitor 1 is an inhibitor of GSK-3.
价 格:¥电议型 号:T11468产 地:美洲
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T11469GSK-3484862GSK-3484862
GSK-3484862 induces DNA hypomethylation to against cancer.?GSK-3484862 is a non-covalent inhibitor for Dnmt1.?
价 格:¥电议型 号:T11469产 地:美洲
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T1147Chlorhexidine hydrochlorideChlorhexidine hydrochloride,Chlorhexidine dihydrochloride,Chlorhexidine 2
Chlorhexidine hydrochloride is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
价 格:¥电议型 号:T1147产 地:美洲
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T11470GSK 366GSK 366
GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 0.7 nM and 2.3 nM for P. fluorescens-KMO (Pf-KMO)?and human KMO, respectively.
价 格:¥电议型 号:T11470产 地:美洲
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T11472GSK 525768AGSK 525768A
GSK 525768A has no activity towards BET. GSK 525768A is the inactive enantiomer of GSK525762A.
价 格:¥电议型 号:T11472产 地:美洲
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T11472LMolibresib besylateMolibresib besylate,GSK 525762C,I-BET 762 besylate
Molibresib besylate is an inhibitor of BET bromodomain (IC50: 32.5-42.5 nM).
价 格:¥电议型 号:T11472L产 地:美洲
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T11476GSK-J2GSK-J2
GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.?GSK-J2 is an isomer of GSK-J1 that does not have any specific activity.?
价 格:¥电议型 号:T11476产 地:美洲
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T11477GSK1059865GSK1059865
GSK1059865 is a potent orexin 1 receptor antagonist.
价 格:¥电议型 号:T11477产 地:美洲
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T1148MenbutoneMenbutone,Genabilic acid,Genabilin
Menbutone is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours.
价 格:¥电议型 号:T1148产 地:美洲
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T11480GSK205GSK205
GSK205 is a potent, selective TRPV4 antagonist with an IC50 of 4.19? μM for inhibiting TRPV4-mediated Ca2+ influx.?
价 格:¥电议型 号:T11480产 地:美洲
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T11481GSK2239633AGSK2239633A
GSK2239633A inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96?±?0.11.?GSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist.
价 格:¥电议型 号:T11481产 地:美洲
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T11483GSK 256066 TrifluoroacetateGSK 256066 Trifluoroacetate,GSK256066 (2,2,2-trifluoroacetic acid),
GSK 256066 Trifluoroacetate developed for the treatment of chronic obstructive pulmonary disease.?GSK 256066 Trifluoroacetate ?is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor, with an IC50 of 3.2 pM for PDE4B.
价 格:¥电议型 号:T11483产 地:美洲
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T11486GSK2807 TrifluoroacetateGSK2807 Trifluoroacetate
GSK2807 Trifluoroacetate is a selective, potent and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM.?
价 格:¥电议型 号:T11486产 地:美洲
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T11487FiboflaponFiboflapon,GSK2190915,AM-803
Fiboflapon ?is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.?
价 格:¥电议型 号:T11487产 地:美洲
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T11487LFiboflapon sodiumFiboflapon sodium,GSK2190915 sodium salt,AM-803 sodium
Fiboflapon sodiumis a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.?
价 格:¥电议型 号:T11487L产 地:美洲
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T11488GSK2850163GSK2850163
GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit ?RNase activity and IRE1α kinase activity with IC50s of 200 and 20 nM, respectively.
价 格:¥电议型 号:T11488产 地:美洲
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T1149FenofibrateFenofibrate,Procetofen,Lipanthyl
Fenofibrate is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
价 格:¥电议型 号:T1149产 地:美洲
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T11492GSK2983559 free acidGSK2983559 free acid
GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.?GSK2983559 free acid ?is a potent, specific and oral bioavailable receptor interacting protein
价 格:¥电议型 号:T11492产 地:美洲
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T11495GSK4028GSK4028
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe,in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay,?the pIC50 of GSK4028 is 4.9.
价 格:¥电议型 号:T11495产 地:美洲