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T2324DarunavirDarunavir,TMC114,
Darunavir is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.
价 格：￥电议型 号：T2324产 地：美洲
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T2660IC-87114IC-87114,IC87114,IC 87114
IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).
价 格：￥电议型 号：T2660产 地：美洲
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T6114NifursolNifursol
Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
价 格：￥电议型 号：T6114产 地：美洲
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T8409SYN1143；化合物AMG-1RON-IN-1|||AMG-1；RON-IN-1|||AMG-1
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
价 格：￥电议型 号：T8409产 地：中国大陆
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T83716KSL-128114 TFA；化合物 KSL-128114 TFAAc-rRrGrKkRrSHWX1X2DI-OH (X1=tert-Leucine; X2=Cyclohexylglycine)；Ac
KSL-128114, a peptide inhibitor of the membrane regulator syntenin (Ki = 300 nM), notably diminishes the viability of A2058 melanoma and patient-derived glioblastoma multiforme (GBM) cells in a concentration-dependent manner. Furthermore, when administered at 50 ?M, KSL-128114 elevates survival times in a patient-derived xenograft (PDX) mouse model of GBM, where mice were implanted intracranially with patient-derived GBM cells pre-cultured with KSL-128114.
价 格：￥电议型 号：T83716产 地：中国大陆
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T83114Angiopep-Bim BH3 hydrochloride；化合物 Angiopep-Bim BH3 hydrochlorideAngiopep-Bim BH3 hydrochloride
Angiopep-Bim BH3 hydrochloride, a peptode that penetrates the blood-brain barrier (BBB), may serve as a tool to study the permeability of central nervous system (CNS) therapeutics [1].
价 格：￥电议型 号：T83114产 地：中国大陆
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T82114ICMT-IN-3；化合物 ICMT-IN-3ICMT-IN-3
ICMT-IN-3 (Compound 27) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.015 μM [1].
价 格：￥电议型 号：T82114产 地：中国大陆
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T81149SMA4；化合物 SMA4SMA4
SMA4, a selective activator of PKG1α, exhibits a basal EC50 of 29 μM, enhances phosphorylation of the PKG1 substrate VASP, and inhibits proliferation of hPASMCs. It is utilized in cardiovascular disease research [1].
价 格：￥电议型 号：T81149产 地：中国大陆
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T81148Smac-based peptide；化合物 Smac-based peptideSmac-based peptide
Smac-based peptide, a biologically active peptide derived from SMAC that interacts with the BIR3 domain, exhibits specific biological functions.
价 格：￥电议型 号：T81148产 地：中国大陆
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T81147SMD-3040 TFA；化合物 SMD-3040 TFASMD-3040 TFA
SMD-3040 TFA is a selective SMARCA2 degrader comprising SMARCA2/4 ligands, a linker, and VHL ligands, utilized in PROTAC drug synthesis. It demonstrates robust tumor growth inhibition in tumor xenograft models [1].
价 格：￥电议型 号：T81147产 地：中国大陆
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T81146SMP-33693；化合物 SMP-33693SMP-33693
SMP-33693 is an Antibody-Drug Conjugate (ADC) known for its low payload shedding rate and demonstrated in vivo tumor inhibition in ovarian, gastric, and breast cancers [1].
价 格：￥电议型 号：T81146产 地：中国大陆
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T81145SMP-88480；化合物 SMP-88480SMP-88480
SMP-88480, an Antibody-Drug Conjugate (ADC), demonstrates stability in mouse, monkey, and human plasma, and exhibits in vivo tumor inhibitory effects on ovarian, gastric, and breast cancers [1].
价 格：￥电议型 号：T81145产 地：中国大陆
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T81144SMP-93566；化合物 SMP-93566SMP-93566
SMP-93566 is an antibody-drug conjugate (ADC) characterized by a low payload shedding rate, demonstrating in vivo tumor suppression in ovarian, gastric, and breast cancers [1].
价 格：￥电议型 号：T81144产 地：中国大陆
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T81143SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3；化合物 SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3SN38-PAB-Lys(MM
"SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a drug-linker conjugate for antibody-drug conjugates (ADCs), consisting of the anti-cancer agent SN38 linked to Lys(MMT)-PAB-oxydiacetamide-PEG8-N3. It serves as a click chemistry reagent featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-bearing molecules and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds containing DBCO or BCN groups, facilitating t
价 格：￥电议型 号：T81143产 地：中国大陆
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T81142SNIPER(TACC3)-1 hydrochloride；化合物 SNIPER(TACC3)-1 hydrochlorideSNIPER(TACC3)-1 hydrochloride
SNIPERTACC3-1 hydrochloride, an IAP ligand-based compound, selectively degrades the TACC3 protein through the ubiquitin-proteasome pathway, thereby inducing cancer cell apoptosis [1].
价 格：￥电议型 号：T81142产 地：中国大陆
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T81141SNIPER(TACC3)-2 hydrochloride；化合物 SNIPER(TACC3)-2 hydrochlorideSNIPER(TACC3)-2 hydrochloride
SNIPER(TACC3)-2 hydrochloride is a compound that induces degradation of the TACC3 protein through the ubiquitin-proteasome pathway by exploiting an IAP ligand, leading to the induction of cancer cell death [1].
价 格：￥电议型 号：T81141产 地：中国大陆
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T81140SNM1A-IN-1；化合物 SNM1A-IN-1SNM1A-IN-1
SNM1A-IN-1 (compound 11a) serves as an inhibitor of the DNA damage repair enzyme SNM1A, exhibiting cytotoxic properties [1].
价 格：￥电议型 号：T81140产 地：中国大陆
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T8114Quercetagetin；栎草亭6-Hydroxyquercetin；栎草亭|||6-Hydroxyquercetin
Quercetagetin (6-Hydroxyquercetin) (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective, cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
价 格：￥电议型 号：T8114产 地：中国大陆
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T81114Spns2-IN-1；化合物 Spns2-IN-1Spns2-IN-1
Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune response [1].
价 格：￥电议型 号：T81114产 地：中国大陆
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T81108SR-1114；化合物 SR-1114SR-1114
SR-1114, a first-in-class PROTAC ENL degrader, induces rapid CRBN-dependent ENL degradation with DC50 values of 150 nM in MV4;11 cells, 311 nM in MOLM-13 cells, and 1.65 μM in OCI/AML-2 cells [1].
价 格：￥电议型 号：T81108产 地：中国大陆
