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T71179LON63114;化合物 LON63114LON63114
LON63114, also known as FFA2-Agonist-1 is a selective orthosteric agonist of human FFA2. FFA2-Agonist-1 is potentially useful in the treatment of gastrointestinal disorders and inflammatory bowel diseases. LON63114 was reported in WO2011076732. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
价 格:¥电议型 号:T71179产 地:中国大陆
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T71149Triptorelin pamoate;化合物 Triptorelin pamoateTriptorelin pamoate
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, es
价 格:¥电议型 号:T71149产 地:中国大陆
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T71148PWT33597 mesylate;化合物 PWT33597 mesylatePWT33597 mesylate
PWT33597, also known as VDC-597, is an orally bioavailable dual inhibitor of phosphatidylinositide 3-kinase (PI3K) alpha and mammalian target of rapamycin (mTOR) kinase with potential antineoplastic activity. PI3K alpha/mTOR dual inhibitor PWT33597 selectively inhibits both PI3K alpha kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in PI3K/mTOR-overexpressing tumor cells.
价 格:¥电议型 号:T71148产 地:中国大陆
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T71147PBS-1086;化合物 PBS-1086PBS-1086
PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.
价 格:¥电议型 号:T71147产 地:中国大陆
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T71146Salvinone;化合物 SalvinoneSalvinone
Salvinone is a platelet aggregation inhibitor isolated from Salvia miltiorrhiza.
价 格:¥电议型 号:T71146产 地:中国大陆
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T71144Nilotinib N-oxide;化合物 Nilotinib N-oxideNilotinib N-oxide
Nilotinib N-oxide is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.
价 格:¥电议型 号:T71144产 地:中国大陆
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T71143Ambroxol-d5;化合物 Ambroxol-d5Ambroxol-d5
Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part
价 格:¥电议型 号:T71143产 地:中国大陆
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T71141Fenspiride-d5;化合物 Fenspiride-d5Fenspiride-d5
Fenspiride-d5 is intended for use as an internal standard for the quantification of fenspiride by GC- or LC-MS. Fenspiride is an antagonist of histamine H1 receptors and a non-steroidal anti-inflammatory drug (NSAID). It inhibits histamine-induced contraction of isolated guinea pig trachea but not histamine-induced inotropy of isolated guinea pig heart. It also inhibits phosphodiesterase 4 (PDE4), PDE5, and PDE3 (IC50s = 69, ~158, and 363 ?M, respectively, in isolated human bronchi derived from
价 格:¥电议型 号:T71141产 地:中国大陆
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T71140MDL-27048;化合物 MDL-27048MDL-27048
MDL-27048 is a powerful and reversible microtubule inhibitor.
价 格:¥电议型 号:T71140产 地:中国大陆
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T7114GALANTHAMINONE;氢溴酸加兰他敏(-)-Narwedine|||Narwedin;(-)-Narwedine|||氢溴酸加兰他敏|||Narwedin
Galanthaminone ((-)-Narwedine) is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer´s disease and various other memory impairments.
价 格:¥电议型 号:T7114产 地:中国大陆
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T71114Mivazerol;化合物 MivazerolMivazerol
Mivazerol is an alpha 2-adrenoceptor agonist.
价 格:¥电议型 号:T71114产 地:中国大陆
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T71033ZD7114 free base;化合物 ZD7114 free baseZD7114 free base
ZD7114, also known as ICI-D7114, is a selective adrenoceptor agonist of brown fat and thermogenesis. ICI D7114 stimulates thermogenesis at doses that have little effect on beta 1 or beta 2 adrenoceptors. Treatment with ICI D7114 activates BAT and thermogenesis even in species and situations where the intrinsic capacity is low. ICI D7114 has beneficial effects in animal models of obesity and disturbed glucose and lipid homeostasis.
价 格:¥电议型 号:T71033产 地:中国大陆
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T70969FR 111142;化合物 FR 111142FR 111142
FR 111142 is an angiogenesis inhibitor produced by the fungus Scolecobasidium arenarium.
价 格:¥电议型 号:T70969产 地:中国大陆
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T70826PF-03671148;化合物 PF-03671148PF-03671148
PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring.
价 格:¥电议型 号:T70826产 地:中国大陆
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T70821FC11409B;化合物 FC11409BFC11409B
FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.
价 格:¥电议型 号:T70821产 地:中国大陆
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T70563KC-11404;化合物 KC-11404KC-11404
KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase.
价 格:¥电议型 号:T70563产 地:中国大陆
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T70532LR 1143;化合物 LR 1143LR 1143
LR 1143 is an inhibitor of dopamine transport.
价 格:¥电议型 号:T70532产 地:中国大陆
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T70114Paclitaxel Ceribate;化合物 Paclitaxel CeribatePaclitaxel Ceribate
Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
价 格:¥电议型 号:T70114产 地:中国大陆
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T6S1141Ganoderic acid A灵芝酸 A灵芝酸 A|||灵芝酸A
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly su
价 格:¥电议型 号:T6S1141产 地:中国大陆
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T69484CGC 11144;化合物 CGC 11144CGC 11144
CGC 11144 is a Polyamine analogue inhibit tumor growth in vitro and in vivo.
价 格:¥电议型 号:T69484产 地:中国大陆