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TN25491-Methoxycarbonyl-β-carboline1 Methoxycarbonyl β carboline,1Methoxycarbonylβcarboline
1-Methoxycarbonyl-β-carboline is an alkaloid from Ailanthus altissima.
价 格:¥电议型 号:TN2549产 地:中国大陆
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T2540Lacosamide
Lacosamide is a functionalized amino acids. Lacosamide modulates sodium channels in a novel manner: It selectively enhances sodium channel slow inactivation with no effects on fast inactivation Lacosamide has demonstrated antiepileptic effectiveness in different rodent seizure models and antinociceptive potential in experimental animal models that reflect distinct types and symptoms of neuropathic as well as chronic inflammatory pain.
价 格:¥电议型 号:T2540产 地:中国大陆
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T7522GI254023XSRI 028594,SRI028594,GI 4023,inhibit,GI-254023X,Matrix metalloproteinases,SRI-028594,Inhibi
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation.
价 格:¥电议型 号:T7522产 地:中国大陆
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T12549JAK-IN-11
JAK-IN-11 is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.
价 格:¥电议型 号:T12549产 地:中国大陆
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T4485LazertinibErbB-1,YH 25448,GNS1480,Lazertinib,EGFR,Inhibitor,YH-25448,Epidermal growth factor recepto
Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.
价 格:¥电议型 号:T4485产 地:中国大陆
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T8254ChrysoobtusinInhibitor,Chrysoobtusin,derivative,anthraquinone,liver,inhibit
Chrysoobtusin belongs to the class of organic compounds known as hydroxyanthraquinones.
价 格:¥电议型 号:T8254产 地:中国大陆
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T13254LUNC10217938A HCl
UNC10217938A HCl is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, leading to enhance oligonucleotides effects. UNC10217938A HCl also enhances the effects of siRNA and antisense oligonucleotides.
价 格:¥电议型 号:T13254L产 地:中国大陆
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TN2254Taccalonolide AMicrotubule/Tubulin,Apoptosis,inhibit,Inhibitor,Taccalonolide A
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protei
价 格:¥电议型 号:TN2254产 地:中国大陆
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T60254Calcium glycerophosphate
Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2].
价 格:¥电议型 号:T60254产 地:中国大陆
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TN25401-Hydroxybaccatin I1 Hydroxybaccatin I,1Hydroxybaccatin I
1-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions.
价 格:¥电议型 号:TN2540产 地:中国大陆
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TN25461-Isomangostin1 Isomangostin,1Isomangostin
1-Isomangostin has cytotoxic and anticomplementary activities.
价 格:¥电议型 号:TN2546产 地:中国大陆
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TP1254[Met5]-Enkephalin, amide TFA[Met5] Enkephalin, amide TFA,[Met-5]-Enkephalin, amide TFA,[Met5]Enkepha
[Met5]-Enkephalin, amide TFA is a δ opioid receptors agonist as well as putative ζ (zeta) opioid receptors.
价 格:¥电议型 号:TP1254产 地:中国大陆
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TQ0066GSK189254AHistamine Receptor,GSK-189254,GSK 189254,GSK-189254A,inhibit,GSK189254A,Inhibitor
GSK189254A is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3).
价 格:¥电议型 号:TQ0066产 地:中国大陆
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T22547Acifran
Acifran is an HM74A/GPR109A and GPR109B agonist and displays antihyperlipidemic activity.
价 格:¥电议型 号:T22547产 地:中国大陆
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T2545Lomitapide MesylateInhibitor,Lomitapide,Lomitapide Mesylate,AEGR-733,inhibit,AEGR 733,BMS-201038,AEG
Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
价 格:¥电议型 号:T2545产 地:中国大陆
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T8862ML 254ML 254,inhibit,ML254,ML-254,Inhibitor,Metabotropic glutamate receptors,mGluR,Schizophrenia
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
价 格:¥电议型 号:T8862产 地:中国大陆
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T6254IdasanutlinRo 5503781;RG7388;依达奴林
Idasanutlin (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
价 格:¥电议型 号:T6254产 地:中国大陆
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T6042[11C]MP 10Mardepodect;PF-2545920
[11C]MP 10, a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.
价 格:¥电议型 号:T6042产 地:中国大陆
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T5S2254SwertianolinBellidifolin-8-O-Glucoside;当药醇苷
1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin and swertiamarin show significant hepatoprotective effect in th
价 格:¥电议型 号:T5S2254产 地:中国大陆