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T7007UNC2025Inhibitor,inhibit,FLT3,leukemia,CD135,Fms like tyrosine kinase 3,acute,Cluster of differentia
UNC-2025（ IC50 of 0.74 nM and 0.8 nM） is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
价 格：￥电议型 号：T7007产 地：中国大陆
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T7001TIC10TIC 10,Tumor Necrosis Factor Receptor,inhibit,ONC201,Inhibitor,TNF Receptor,Apoptosis,TNFR,ONC
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格：￥电议型 号：T7001产 地：中国大陆
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T6610NSC-207895XI006,MDMX,p53,LPS,Inhibitor,XI 006,MDM2,inhibit,MDM-2/p53,NSC-207895,NSC207895
NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
价 格：￥电议型 号：T6610产 地：中国大陆
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T8561Apcinligase,pocket,anaphase-promoting,Apcin,recognition,complex,Inhibitor,Cdc20,Anaphase promoting c
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe.
价 格：￥电议型 号：T8561产 地：中国大陆
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T37428TRPC6-PAM-C20
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced platelet aggregation.
价 格：￥电议型 号：T37428产 地：中国大陆
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T7089SGC2085SGC2085,SGC 2085,Inhibitor,inhibit,SGC-2085,Histone Methyltransferase
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).
价 格：￥电议型 号：T7089产 地：中国大陆
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T8993LBGC-20-1531 hydrochloride(1186532-61-5 free base)BGC201531 hydrochloride(1186532615 free base),BGC 2
BGC201531 hydrochloride is a EP4 antagonist for the treatment of acute migraine.
价 格：￥电议型 号：T8993L产 地：中国大陆
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T6362Domatinostat4SC-202；4SC-202 (free base)；4SC 202；4SC202
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
价 格：￥电议型 号：T6362产 地：中国大陆
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T5642TegatrabetanBC2059
BC2059 is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
价 格：￥电议型 号：T5642产 地：中国大陆
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T5341WYC-209WYC209
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
价 格：￥电议型 号：T5341产 地：中国大陆
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T4419UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
价 格：￥电议型 号：T4419产 地：中国大陆
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T4013SGC2085 HCl
SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription a
价 格：￥电议型 号：T4013产 地：中国大陆
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T33514MSC 2032964AMSC-2032964A；MSC2032964A
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
价 格：￥电议型 号：T33514产 地：中国大陆
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T2585Bedaquiline贝达喹啉；TMC207；R207910
Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
价 格：￥电议型 号：T2585产 地：中国大陆
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T2345PTC-209PTC209；PTC 209
PTC-209 is a potent and selective BMI-1 inhibitor.
价 格：￥电议型 号：T2345产 地：中国大陆
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T2234TCS JNK 5aN-(3-氰基-4,5,6,7-四氢苯并[b]噻吩-2-基)-1-萘甲酰胺；SC-202671；SC202671；SC 202671；N-(3-Cyano-4,5,6,7-tetr
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
价 格：￥电议型 号：T2234产 地：中国大陆
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T21023Bedaquiline fumarate贝达喹啉富马酸盐；R 403323；R-403323；R403323；TMC 207；TMC-207；TMC207
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. It is the first member of a new class of dru
价 格：￥电议型 号：T21023产 地：中国大陆
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T2095SeliciclibRoscovitine；R-roscovitine；CYC202
Roscovitine is a potent inhibitor of Cdk2/cyclin E (IC50: 0.1 μM). It also inhibits Cdk7/cyclin H, Cdk5/p35, and Cdc2/cyclin B (IC50s: 0.49/0.16/0.65 μM).
价 格：￥电议型 号：T2095产 地：中国大陆
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T1687LDoxycycline (hyclate)盐酸强力霉素；WC2031；Doxycycline hydrochloride hemiethanolate hemihydrate；Doxycycline
Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity. It is also an inhibitor of matrix metalloproteinases (MMP).
价 格：￥电议型 号：T1687L产 地：中国大陆
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T16392ONC206
ONC206 is an analogue of TRAIL inducer ONC201 and is a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations. ONC206 also has broad-spectrum anti-tumor activity.
价 格：￥电议型 号：T16392产 地：中国大陆
