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T9402Thalidomide-O-C4-NH2 hydrochlorideThalidomide O C4 NH2 hydrochloride,E3 Ligase Ligand-Linker Conjuga
Thalidomide-linker 9 is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格:¥电议型 号:T9402产 地:中国大陆
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T60028MM41inhibit,G-quadruplex,MM41,MM 41,PaCa-2,pancreatic cancer,A549,Inhibitor,cancer,stabilizer,RCC4,7
MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.
价 格:¥电议型 号:T60028产 地:中国大陆
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T8930CID44216842diseases,neutrophils,ovarian,disorders,Cdc42,fibroblasts,breast,hepatitis C,CID 44216842,
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
价 格:¥电议型 号:T8930产 地:中国大陆
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T8985NSC45586pleckstrin homology domain and leucine-rich repeat protein phosphatase,NSC-45586,NSC45586,in
NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
价 格:¥电议型 号:T8985产 地:中国大陆
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T60148MSC-4106MSC4106
MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and exhibits inhibitory effect on NCI-H226 tumor xenograft model [1].
价 格:¥电议型 号:T60148产 地:中国大陆
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TP1561123C4Inhibitor,123C-4,123C4,Ephrin Receptor,inhibit
123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase?EPHA4 (Ki=0.65 μM)[1].
价 格:¥电议型 号:TP1561产 地:中国大陆
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T15648KDM5-C70KDM5-C49,Histone Demethylase,JARID1,retinoblastoma,inhibit,KDM5 C70,KDM5-C70,KDM-5-C70,phosp
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide elevation of H3K4me3 levels.
价 格:¥电议型 号:T15648产 地:中国大陆
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T7759Thalidomide-O-amido-C4-NH2 TFAThalidomide O amido C4 NH2 TFA,inhibit,ThalidomideOamidoC4NH2 TFA,E3 l
Thalidomide-O-amido-C4-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate.
价 格:¥电议型 号:T7759产 地:中国大陆
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T6796CB-5083Inhibitor,inhibit,multiple,p97,VCP,solid,tumors,myeloma,AAA,ATPase,Cdc48,CB-5083
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
价 格:¥电议型 号:T6796产 地:中国大陆
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T28206NSC49652NSC49652
NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.
价 格:¥电议型 号:T28206产 地:中国大陆
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T18640(S,R,S)-AHPC-C4-NH2 hydrochlorideinhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydroch
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格:¥电议型 号:T18640产 地:中国大陆
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T6400AZD3514selective,anti proliferation,LAPC4,Inhibitor,AZD3514,AZD-3514,oral,AZD 3514,rat,AR protein,pr
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
价 格:¥电议型 号:T6400产 地:中国大陆
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T7213Demecarium bromideInhibitor,BC48,Demecarium,Demecarium bromide,inhibit,BC 48,Cholinesterase (ChE)
Demecarium bromide is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
价 格:¥电议型 号:T7213产 地:中国大陆
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T5833CC-401 HydrochlorideCC401 HCl
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.
价 格:¥电议型 号:T5833产 地:中国大陆
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T5398BMS 599626 2HCl (873837-23-1(HCl))AC480 dihydrochloride
BMS-599626 (AC480) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.
价 格:¥电议型 号:T5398产 地:中国大陆
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T4686Simeprevir西咪匹韦;TMC-435350;TMC435
Simeprevir is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
价 格:¥电议型 号:T4686产 地:中国大陆
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T40014Pomalidomide-C4-OH
Pomalidomide-C4-OH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40014产 地:中国大陆
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T40009Pomalidomide-C4-COOH
Pomalidomide-C4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40009产 地:中国大陆
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T3323Ursonic Acid熊果酮酸;熊果酸;TOS-BB-0966;3-Ketoursolic acid;Malol;Prunol;CCRIS 7123;NSC4060
Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
价 格:¥电议型 号:T3323产 地:中国大陆
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T3211MidostaurinCGP 41251;CGP41231;PKC412;N-Benzoylstaurosporine;米哚妥林;苯甲酰基十字孢碱
PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) an
价 格:¥电议型 号:T3211产 地:中国大陆