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产品数:86101
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已选条件
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T6683STF-62247renal,STF-62247,VHL,carcinoma,inhibit,cytotoxic,cell,RCC,Inhibitor,STF62247,intracytoplasmi
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
价 格:¥电议型 号:T6683产 地:中国大陆
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T8799(E/Z)-IT-603GVHD,Inhibitor,Nuclear factor-kappaB,(E/Z)IT603,immunomodulatory,(E/Z) IT 603,disease,in
IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity.
价 格:¥电议型 号:T8799产 地:中国大陆
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T29106VH032VH032
VH032 commonly used as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component.VH032 is a VHL/HIF-1α interaction inhibitor with a KdPROTACs, which can recruit von Hippel-Lindau (VHL) proteins as a ligand of VHL.
价 格:¥电议型 号:T29106产 地:中国大陆
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T7752(S,R,S)-AHPC-MeVHL ligand-2,VHL ligand2,Inhibitor,inhibit,Ligands for E3 Ligase,(S,R,S) AHPC Me,(S,R
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
价 格:¥电议型 号:T7752产 地:中国大陆
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TQ0121VH-298E3 ligase-recruiting Moiety,VH-298,Inhibitor,VH298,Ligands for E3 Ligase,VH 298,inhibit
VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by PHD enzymes.
价 格:¥电议型 号:TQ0121产 地:中国大陆
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T35478cis VH 032, amine dihydrochloride
cis VH 032, amine dihydrochloride is a negative control for the functionalized VHL ligand VH 032, amine .
价 格:¥电议型 号:T35478产 地:中国大陆
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T4207(S,R,S)-AHPC hydrochlorideVHL Ligand 1 hydrochloride;Protein degrader 1 hydrochloride;ULM-1
Protein degrader 1 hydrochloride is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
价 格:¥电议型 号:T4207产 地:中国大陆
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T18675(S,R,S)-AHPC-PEG2-NH2 dihydrochloride(S,R,S)-AHPC-PEG2-NH2二盐酸盐;VH032 amide-PEG2-amine;VH032-PEG2-NH2
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1].
价 格:¥电议型 号:T18675产 地:中国大陆
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T18661(S,R,S)-AHPC-C10-NH2 dihydrochloride(S,R,S)-AHPC-C10-NH2二盐酸盐;VH032 amide-alkylC10-amine;VH032-C10-NH
(S,R,S)-AHPC-C10-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].
价 格:¥电议型 号:T18661产 地:中国大陆
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T17927(S,R,S)-AHPC TFAVHL ligand 1 TFA;VH032-NH2 TFA
(S,R,S)-AHPC TFA (VH032-NH2 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-47
价 格:¥电议型 号:T17927产 地:中国大陆
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T17924(S,R,S)-AHPC-PEG2-NH2 hydrochlorideVHL Ligand-Linker Conjugates 3 hydrochloride;VH032-PEG2-NH2 hydro
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17924产 地:中国大陆
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T17920(S,R,S)-AHPC-PEG1-N3E3 ligase Ligand-Linker Conjugates 3;VHL Ligand-Linker Conjugates 9;VH032-PEG1-N
(S,R,S)-AHPC-PEG1-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17920产 地:中国大陆
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T17913(S,R,S)-AHPC-PEG2-N3VHL Ligand-Linker Conjugates 6;E3 ligase Ligand-Linker Conjugates 13;VH032-PEG2-
(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.
价 格:¥电议型 号:T17913产 地:中国大陆
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T17909(S,R,S)-AHPC-PEG3-N3E3 ligase Ligand-Linker Conjugates 12;VHL Ligand-Linker Conjugates 8;VH032-PEG3-
(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17909产 地:中国大陆
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T17877VH032-cyclopropane-FPhenolic VH101;VHL ligand 3;E3 ligase Ligand 19
VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
价 格:¥电议型 号:T17877产 地:中国大陆
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T13877(S,S,S)-AHPC hydrochloride(S,S,S)-AHPC盐酸盐;(S,S,S)-VH032-NH2 hydrochloride
(S,S,S)-AHPC hydrochloride is a VHL amino building block, is a ligand used as a negative control for (S,R,S)-AHPC. It is the VH032-based VHL ligand used in the recruitment of the VHL protein.
价 格:¥电议型 号:T13877产 地:中国大陆
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T13722Homo-PROTAC pVHL30 degrader 1
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
价 格:¥电议型 号:T13722产 地:中国大陆
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T13671(S,R,S)-AHPC-Me hydrochlorideVHL ligand 2 hydrochloride;E3 ligase Ligand 1
(S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM. (S,R,S)-AHPC-Me h
价 格:¥电议型 号:T13671产 地:中国大陆
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T13722Homo-PROTAC pVHL30 degrader 1Homo-PROTAC pVHL30 degrader 1
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
价 格:¥电议型 号:T13722产 地:美洲
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T13876(S,R,S)-AHPC-propargyl(S,R,S)-AHPC-propargyl,VH032-propargyl,VHL ligand 7
(S,R,S)-AHPC-propargyl is a VHL ligand which is used in “click reaction” for PROTACs.
价 格:¥电议型 号:T13876产 地:美洲