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T10526β-NF-JQ1;化合物β-NF-JQ1β-NF-JQ1
β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins. β-NF-JQ1 uses β-NF as an AhR ligand to target bromodomain (BRD)-containing proteins and induce AhR and BRD protein interactions. β-NF-JQ1 shows potent anticancer activity associated with protein knockdown activity. .
价 格:¥电议型 号:T10526产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆
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T10420Avarofloxacin;化合物 T10420JNJ-Q2;JNJ-Q2
Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
价 格:¥电议型 号:T10420产 地:中国大陆
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T10009JAK3-IN-7;JAK3抑制剂7JAK3-IN-7
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after organ transplantation, autoimmune disorders, allergic diseases, and chronic myeloproliferative disorders.
价 格:¥电议型 号:T10009产 地:中国大陆
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T0991Desipramine hydrochloride盐酸去甲咪嗪NSC-114901|||Desmethylimipramine|||盐酸去甲咪嗪|||JB-8181|||EX-4355|||Norim
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.
价 格:¥电议型 号:T0991产 地:中国大陆
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T0675Topiramate;托吡酯RWJ 17021|||McN 4853;RWJ 17021|||McN 4853|||托吡酯
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination with other anticonvulsant medications.
价 格:¥电议型 号:T0675产 地:中国大陆
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Fr13138Jedi2;化合物 Jedi2Jedi2
Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].
价 格:¥电议型 号:Fr13138产 地:中国大陆
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L3700JAK-STAT 化合物库
TargetMol JAK-STAT 化合物库是256个JAK/STAT靶点相关的小分子化合物的独特集合,用于JAK/STAT靶点相关的研究以及药物的筛选,可用于高通量、高内涵筛选。
价 格:¥电议型 号:L3700产 地:中国大陆