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T2367SKF-86002；化合物SKF-86002SKF86002；SKF86002
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
价 格：￥电议型 号：T2367产 地：中国大陆
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T23365SKF-86002 dihydrochloride；化合物 T23365SKF 86002 dihydrochloride；SKF 86002 dihydrochloride
p38 MAP kinase inhibitor
价 格：￥电议型 号：T23365产 地：中国大陆
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T22860Imeglimin；化合物 T22860Imeglimin
Imeglimin is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents. It has been shown to act on the liver, muscle, and pancreatic β-cells to uniquely target the key defects of type 2 diabetes.
价 格：￥电议型 号：T22860产 地：中国大陆
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T22763EMD 386088 hydrochloride化合物 T22763EMD 386088 hydrochloride
EMD 386088 hydrochloride is a 5-HT6 receptor agonist.
价 格：￥电议型 号：T22763产 地：中国大陆
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T21860Asterric Acid；化合物 T21860Asterric Acid
Asterric Acid is a useful organic compound for research related to life sciences. The catalog number is T21860 and the CAS number is 577-64-0.
价 格：￥电议型 号：T21860产 地：中国大陆
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T20860Hydroxy-PEG12-t-butyl ester；化合物 T20860Hydroxy-PEG12-t-butyl ester
Hydroxy-PEG12-t-butyl ester is a PEG derivative containing a hydroxyl group and a t-butyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.
价 格：￥电议型 号：T20860产 地：中国大陆
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T19860Clavulanic Acid克拉维酸BRL 14151|||MM-14151|||MM 14151|||RX-10100|||MM14151|||BRL14151|||BRL-14151
Clavulanic Acid(RX-10100), a major beta-lactam antibiotic produced by the organism Streptomyces claveris, is a potent bacterial beta-lactamase inhibitor used in the study of infections caused by bacteria. Clavulanic Acid has a broad spectrum of biological activity and is active against a wide variety of Gram-positive and Gram-negative bacteria.
价 格：￥电议型 号：T19860产 地：中国大陆
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T19656Pyrazolynate；化合物 T19656SW-751|||BRN 0860937|||Pyrazolate；SW-751|||BRN 0860937|||Pyrazolate
Pyrazolynate is a herbicide. It is used to evaluate the hydrolyzation to destosyl pyrazolynate (DTP).
价 格：￥电议型 号：T19656产 地：中国大陆
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T18860Tri-(PEG1-C2-acid)；化合物 T18860Tri-(PEG1-C2-acid)
Tri-(PEG1-C2-acid) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18860产 地：中国大陆
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T18609PROTAC ERRα Degrader-2；化合物 T18609PROTAC ERRα Degrader-2
PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group. This compound is designed to specifically degrade estrogen-related receptor alpha (ERRα), acting as an ERRα degrader[1].
价 格：￥电议型 号：T18609产 地：中国大陆
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T18607PROTAC ER Degrader-3；化合物 T18607PROTAC ER Degrader-3
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) compared to PROTAC alone [1].
价 格：￥电议型 号：T18607产 地：中国大陆
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T18606PROTAC ER Degrader-2；化合物 T18606PROTAC ER Degrader-2
PROTAC ER Degrader-2 serves as a synthesis intermediate for the production of PAC, a compound that incorporates the ADCs linker and PROTACs, which are subsequently conjugated to an antibody. PAC, exhibits a greater capability to degrade estrogen receptor-alpha (ERα) compared to PROTAC (without the presence of an antibody)[1].
价 格：￥电议型 号：T18606产 地：中国大陆
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T18605PROTAC ERα Degrader-2；化合物 T18605PROTAC ERα Degrader-2
PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader. It achieves maximal ERα degradation in human mammary tumor MCF7 cells at a concentration of 30 μM. Degradation inducers that utilize cIAP1 are referred to as specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].
价 格：￥电议型 号：T18605产 地：中国大陆
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T18603PROTAC BRD4 degrader for PAC-1；化合物 T18603PROTAC BRD4 degrader for PAC-1
PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective proteolysis of PAC-1.
价 格：￥电议型 号：T18603产 地：中国大陆
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T18602VH032-thiol-C6-NH2；化合物 T18602VHL Ligand-Linker Conjugates 14|||E3 ligase Ligand-Linker Conjugates 29
VH032-thiol-C6-NH2, also known as VHL Ligand-Linker Conjugates 14, is a synthesized compound that functions as an E3 ligase ligand-linker conjugate. This compound combines the VH032 based VHL ligand with a linker commonly utilized in PROTAC technology.
价 格：￥电议型 号：T18602产 地：中国大陆
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T18601Desmethyl-QCA276；化合物 T18601PROTAC BRD4-binding moiety 4；PROTAC BRD4-binding moiety 4
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
价 格：￥电议型 号：T18601产 地：中国大陆
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T18600VH032 thiol；化合物 T18600VHL ligand 6；VHL ligand 6
VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.
价 格：￥电议型 号：T18600产 地：中国大陆
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T1860Imepitoin；伊匹妥英AWD 131-138|||ELB-138；AWD 131-138|||ELB-138|||伊匹妥英
Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
价 格：￥电议型 号：T1860产 地：中国大陆
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T17860DSPE-PEG46-DBCO；化合物 T17860DSPE-PEG46-DBCO
DSPE-PEG46-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17860产 地：中国大陆
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T17156Tradipitant；化合物TradipitantVLY-686|||LY686017；VLY-686|||LY686017
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
价 格：￥电议型 号：T17156产 地：中国大陆
