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T77860TCO-PEG4-VC-PAB-MMAE;化合物 TCO-PEG4-VC-PAB-MMAETCO-PEG4-VC-PAB-MMAE
TCO-PEG4-VC-PAB-MMAE is an agent-linker conjugate utilized in antibody-drug conjugates (ADCs), comprising a cleavable linker (TCO-PEG4-VC-PA) and the potent tubulin inhibitor MMAE [1].
价 格:¥电议型 号:T77860产 地:中国大陆
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T76774Ponsegromab;Ponsegromab单抗PF 06946860;PF 06946860
Ponsegromab (PF 06946860) is a selective and effective humanized anti-GDF15 antibody inhibitor. Ponsegromab has anti-cachexic activity by binding to GDF15 to prevent its binding to GFRAL, thus disrupting GDF15/GFRAL mediated signaling. Ponsegromab has potential anticancer activity and can be used to treat cancer patients with cancer anorexia cachexia syndrome.
价 格:¥电议型 号:T76774产 地:中国大陆
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T75860GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS;化合物 GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPSGTFTSDVSKQMEEEAVRLFIEWL
GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.
价 格:¥电议型 号:T75860产 地:中国大陆
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T74860MAO-B-IN-21;化合物 MAO-B-IN-21MAO-B-IN-21
MAO-B-IN-21 is an MAO-B inhibitor characterized by superior antioxidant and anti-Aβ aggregation activities. The compound additionally shows metal-ion chelating capabilities, mitigates neuroinflammation (NO, TNF-α), and demonstrates neuroprotective effects with notable BBB permeability. In an Aβ1-42 induced Alzheimer´s disease mouse model, MAO-B-IN-21 markedly enhances memory and cognitive functions [1].
价 格:¥电议型 号:T74860产 地:中国大陆
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T7361Verucerfont;化合物VerucerfontNBI77860|||GSK561679;NBI77860|||3-(4-甲氧基-2-甲基苯基)-2,5-二甲基-N-[(1S)-1-(3-甲基-1
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
价 格:¥电议型 号:T7361产 地:中国大陆
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T72860(R)-Olacaftor;化合物 (R)-Olacaftor(R)-VX-440;(R)-VX-440
(R)-Olacaftor ((R)-VX-440), a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator, shows promising potential in cystic fibrosis (CF) research.
价 格:¥电议型 号:T72860产 地:中国大陆
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T72462(2S,5S)-Censavudine;化合物 (2S,5S)-Censavudine(2S,5S)-OBP-601 ; (2S,5S)-BMS-986001|||(2S,5S)-BMS-98600
(2S,5S)-Censavudine ((2S,5S)-OBP-601), the (2S,5S)-enantiomer of Censavudine, is a nucleoside reverse transcriptase inhibitor and a potent HIV inhibitor.
价 格:¥电议型 号:T72462产 地:中国大陆
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T71860Ambuic acid;化合物 Ambuic acidAmbuic acid
Ambuic acid is a cyclohexanone that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when adminis
价 格:¥电议型 号:T71860产 地:中国大陆
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T70860Banoxantrone;化合物 Banoxantrone (AQ4N)AQ4N;AQ4N
Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. This compound demonstrates significant cytotoxicity with its hypoxia-selective action being augmented by radiation.
价 格:¥电议型 号:T70860产 地:中国大陆
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T70370PF-06658607;化合物 PF-06658607PF-06658607
PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor.
价 格:¥电议型 号:T70370产 地:中国大陆
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T69949CGP-78608;化合物 CGP-78608CGP-78608
CGP-78608 is a glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.
价 格:¥电议型 号:T69949产 地:中国大陆
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T69860PSB-15160;化合物PSB-15160PSB-15160
PSB-15160 is a compound that inhibits the growth of MCF7 (breast), NCI-H460 (lung) and SF-268 (NCS) cells in the treatment of estrogen-dependent tumours.
价 格:¥电议型 号:T69860产 地:中国大陆
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T6930Pazopanib Hydrochloride;盐酸帕唑帕尼GW786034|||Pazopanib HCl|||GW786034 HCl|||Votrient HCl|||Armala;GW7860
Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
价 格:¥电议型 号:T6930产 地:中国大陆
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T68860Iso-Fludelone;化合物 Iso-FludeloneIso-Fludelone
Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to other generations of epothilones, iso-fludelone exhibits increased stability, water solubility, potency, duration of action, tumor penetration as we
价 格:¥电议型 号:T68860产 地:中国大陆
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T68609Batebulast hydrochloride;化合物 Batebulast hydrochlorideBatebulast hydrochloride
Batebulast hydrochloride is a Histamine H1 Antagonist.
价 格:¥电议型 号:T68609产 地:中国大陆
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T68608Methylnaltrexone;化合物 MethylnaltrexoneMethylnaltrexone
Methylnaltrexone is a narcotic antagonists.
价 格:¥电议型 号:T68608产 地:中国大陆
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T68606Ciladopa hydrochloride;化合物 Ciladopa hydrochlorideCiladopa hydrochloride
Ciladopa hydrochloride is a dopaminergic agonist that may be useful in the treatment of Parkinson´s disease.
价 格:¥电议型 号:T68606产 地:中国大陆
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T68605JNJ-4929821;化合物 JNJ-4929821JNJ-4929821
JNJ-4929821 is a potent, reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 8 nM.
价 格:¥电议型 号:T68605产 地:中国大陆
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T68604Piperazinomycin;化合物 PiperazinomycinPiperazinomycin
Piperazinomycin is an antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton.
价 格:¥电议型 号:T68604产 地:中国大陆