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T38860Golodirsen;GolodirsenGolodirsen|||SRP-4053;Golodirsen|||SRP-4053
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) designed to selectively bind and target exon 53 of dystrophin pre-mRNA, with applications in the investigation of Duchenne muscular dystrophy (DMD).
价 格:¥电议型 号:T38860产 地:中国大陆
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T38609Mycalolide B;Mycalolide BMycalolide B
Mycalolide-B is a marine sponge-derived compound that functions as a selective inhibitor of actomyosin ATPase. It effectively hinders ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+.
价 格:¥电议型 号:T38609产 地:中国大陆
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T38608Brilacidin tetrahydrochloride;Brilacidin tetrahydrochloridePMX 30063 tetrahydrochloride;PMX 30063 te
Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of 1 μg/mL and 8 μg/mL against the Gram-positive bacteria Streptococcus pneumoniae and Streptococcus viridans, respectively. Additionally, it has a MIC90 value of 8 μg/mL for the Gram-negative bacteria Haemophilus influenzae and a MIC90 value of 4 μg/mL for Pseudomonas aeruginosa.
价 格:¥电议型 号:T38608产 地:中国大陆
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T38607Etoposide phosphate disodiumEtoposide phosphate disodiumBMY-40481 disodium|||Etoposide phosphate dis
Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, functions as a potent chemotherapeutic agent by selectively inhibiting topoisomerase II, hindering the re-ligation of DNA strands. It is regarded as the active equivalent of etoposide, effectively inducing cell cycle arrest, apoptosis, and autophagy in cancer cells.
价 格:¥电议型 号:T38607产 地:中国大陆
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T38606Sinapine hydroxide;Sinapine hydroxideSinapine hydroxide
Sinapine hydroxide, an alkaloid derived from the seeds of cruciferous plants, demonstrates a variety of beneficial properties including anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic, and radio-protective effects. Additionally, it acts as an inhibitor of acetylcholinesterase (AChE), making it valuable for researching neurodegenerative conditions such as Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[4].
价 格:¥电议型 号:T38606产 地:中国大陆
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T38605NCT-504;化合物NCT-504NCT-504
NCT-504, a selective allosteric inhibitor of PIP4Kγ, exhibits an IC50 value of 15.8 μM. It holds promise for the investigation of Huntington´s disease.
价 格:¥电议型 号:T38605产 地:中国大陆
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T38604C12-200;化合物C12-200C12-200;C12-200
C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids and can be used in the delivery of mRNA.
价 格:¥电议型 号:T38604产 地:中国大陆
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T38603Vitronectin (367-378);Vitronectin (367-378)Vitronectin (367-378)
Vitronectin (367-378) is a peptide derived from residues 367-378 of the multifunctional glycoprotein known as Vitronectin. Vitronectin plays a pivotal role in cell growth, angiogenesis, and metastasis within various human tumors.
价 格:¥电议型 号:T38603产 地:中国大陆
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T38602(E/Z)-Eltrombopag 13C4;(E/Z)-Eltrombopag 13C4(E/Z)-Eltrombopag 13C4|||(E/Z)-SB-497115 13C4;(E/Z)-Elt
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia.
价 格:¥电议型 号:T38602产 地:中国大陆
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T38601GYKI-47261 dihydrochloride;GYKI-47261 dihydrochlorideGYKI-47261 dihydrochloride
GYKI-47261 dihydrochloride is a selective AMPA receptor antagonist, administered orally, and exhibits competitive activity with an IC 50 of 2.5 μM. It displays a wide range of anticonvulsive effects and demonstrates neuroprotective properties. Additionally, GYKI-47261 dihydrochloride is a potent inducer of CYP2E1.
价 格:¥电议型 号:T38601产 地:中国大陆
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T38600N-ε-propargyloxycarbonyl-L-lysineN-ε-propargyloxycarbonyl-L-lysineN-ε-propargyloxycarbonyl-L-lysine|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is an unnatural amino acid (UAA) derived from lysine. It is commonly employed for bio-conjugation purposes, specifically for attaching fluorescent probes in a variety of organisms ranging from E. coli to mammalian cells, including animals.
价 格:¥电议型 号:T38600产 地:中国大陆
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T3860Isoliquiritin apioside;芹糖异甘草苷Isoliquiritin apioside
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells. Isoliquiritin apioside has marked potential to combat oxidative stress-induced genotoxicity.
价 格:¥电议型 号:T3860产 地:中国大陆
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T37860T 26c disodium salt;T 26c disodium saltT 26c disodium|||T 26c|||T 26c disodium salt;T 26c disodium||
Highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable.
价 格:¥电议型 号:T37860产 地:中国大陆
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T36995MRT 68601 hydrochloride;MRT 68601 hydrochlorideMRT 68601 hydrochloride
Potent TBK1 (TANK-binding kinase-1) inhibitor (IC50 = 6 nM). Inhibits the formation of autophagosomes in lung cancer cells.
价 格:¥电议型 号:T36995产 地:中国大陆
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T36860C22 Sphingomyelin (d18:1/22:0);C22 Sphingomyelin (d18:1/22:0)C22 Sphingomyelin (d18:1/22:0);C22 Sphi
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyelin levels are decreased in T-47D mammary epithelial cells and increased in MDA-MB-231 breast cancer cells relative to C16 sphingomyelin .
价 格:¥电议型 号:T36860产 地:中国大陆
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T35860AP39;AP39AP39|||AP 39|||AP-39|||AP-39|||AP39;AP39|||AP 39|||AP-39|||AP-39|||AP39
AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP39 (30-300 nM) dose-dependently increases H2S levels in endothelial cells, predominantly in mitochondrial regions. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an i
价 格:¥电议型 号:T35860产 地:中国大陆
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T34401Roxoperone;化合物 T34401R 7158|||F-33|||FR-33|||NSC 186062|||Roxoperon;R 7158|||F-33|||FR-33|||NSC 1860
Roxoperone is a bioactive chemical.
价 格:¥电议型 号:T34401产 地:中国大陆
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T34376RO5488608;化合物 T34376RO 5488608|||RO-5488608;RO 5488608|||RO-5488608
RO5488608 is a new type of high-efficiency mGlu2/3 NAM.
价 格:¥电议型 号:T34376产 地:中国大陆
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T34239R 8605;化合物 T34239R-8605|||R8605;R-8605|||R8605
R 8605 is a third-generation retinoid.
价 格:¥电议型 号:T34239产 地:中国大陆