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T71157Neladenoson dalanate;化合物 Neladenoson dalanateNeladenoson bialanate ; BAY-1067197|||BAY-1067197|||Ne
Neladenoson dalanate (Neladenoson bialanate; BAY-1067197) is an orally active partial agonist precursor targeting the Adenosine A1 Receptor, demonstrating a favorable pharmacokinetic and safety profile. It is indicated for the management of chronic heart diseases.
价 格:¥电议型 号:T71157产 地:中国大陆
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T71109BAY-386;化合物 BAY-386BAY-386
BAY-386 is a PAR1 receptor inhibitor which suppresses activation of thrombin and platelet activity.
价 格:¥电议型 号:T71109产 地:中国大陆
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T71037BAY-438;化合物 BAY-438BAY-438
BAY-438 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
价 格:¥电议型 号:T71037产 地:中国大陆
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T70377BAY 61-3606 HCl;化合物 BAY 61-3606 HClBAY 61-3606 HCl
BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used i
价 格:¥电议型 号:T70377产 地:中国大陆
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T70133BAY-846;化合物 BAY-846BAY-846
BAY-846 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
价 格:¥电议型 号:T70133产 地:中国大陆
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T69776BAY-707 acetate;化合物 BAY-707 acetateBAY-707 acetate
BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1. Despite superior cellular target engagement and pharmacokinetic properties, inhibition of MTH1 with BAY-707 resulted in a clear lack of in vitro or in vivo anticancer efficacy either in mono- or in combination therapies.
价 格:¥电议型 号:T69776产 地:中国大陆
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T69703BAY-6035-R-isomer;化合物 BAY-6035-R-isomerBAY-6035-R-isomer
BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.
价 格:¥电议型 号:T69703产 地:中国大陆
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T69689BAY-693;化合物 BAY-693BAY-693
BAY-693 is a ERK5 negative control agent with IC50 (ERK5) = 6400 nM. Its analog, BAY-885, is a potent and selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM
价 格:¥电议型 号:T69689产 地:中国大陆
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T6968Riociguat;利奥西呱BAY 632521;利奥西呱|||BAY 632521
Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
价 格:¥电议型 号:T6968产 地:中国大陆
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T69518BAY-771;化合物 BAY-771BAY-771
BAY-771 is a negative control of BAY-069, BAY-069 is a BCAT1/2 Inhibitor and Chemical Probe. BAY-069 displays high cellular activity and very good selectivity. BAY-069 displays high cellular activity. Its overall in vivo pharmacokinetic profile and its selectivity in various in vitro panels suggest that BAY-069 is suitable for in vivo experiments.
价 格:¥电议型 号:T69518产 地:中国大陆
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T6915Darolutamide;化合物DarolutamideODM-201|||BAY-1841788;ODM-201|||BAY-1841788
Darolutamide (BAY-1841788) is an androgen receptor (AR) antagonist that blocks AR nuclear translocation (Ki: 11 nM).
价 格:¥电议型 号:T6915产 地:中国大陆
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T68896Daniquidone;达尼喹酮NSC 320846|||BAY-H 2049;NSC 320846|||BAY-H 2049
Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity that induces DNA fragmentation for the study of neoplasms, immune disorders, and lymphatic disorders.
价 格:¥电议型 号:T68896产 地:中国大陆
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T67936BAY-0069;化合物BAY-0069BAY-0069
BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research.
价 格:¥电议型 号:T67936产 地:中国大陆
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T67933BAY-4931;化合物BAY-4931BAY-4931
BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.
价 格:¥电议型 号:T67933产 地:中国大陆
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T67927BAY-069;化合物BAY-069BAY-069
BAY-069 is an inhibitor. BAY-069 inhibited branched-chain amino acid transaminase 1 (BCAT1) at IC50:31 nM and branched-chain amino acid transaminase 2 (BCAT2) at IC50:153 nM. BAY-069 is a novel (trifluoromethyl) pyrimidine dione chemical probe, which can be used for anticancer research.
价 格:¥电议型 号:T67927产 地:中国大陆
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T67788BAY-43-9695;化合物BAY-43-9695BAY-43-9695
BAY-43-9695 is a non-nucleoside compound with anti-human cytomegalovirus (HCMV) activity. It is the major metabolite of BAY-38-4766.
价 格:¥电议型 号:T67788产 地:中国大陆
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T6777Bay K 8644;化合物Bay K 8644(±)-BAY-K-8644|||SQ 28,873;(±)-BAY-K-8644|||SQ 28,873
Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
价 格:¥电议型 号:T6777产 地:中国大陆
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T6776BAY 61-3606 dihydrochloride;化合物BAY-61-3606BAY 61-3606|||BAY-61-3606 dihydrochloride;BAY 61-3606|||BA
BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
价 格:¥电议型 号:T6776产 地:中国大陆
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T6775BAY 41-2272;化合物BAY 41-2272BAY 41-2272
BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.
价 格:¥电议型 号:T6775产 地:中国大陆
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T6636Refametinib;瑞法替尼//瑞美替尼BAY 86-97661|||BAY 869766|||RDEA119;BAY 86-97661|||瑞法替尼//瑞美替尼|||BAY 869766|||R
Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).
价 格:¥电议型 号:T6636产 地:中国大陆