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  • T77412Lupartumab；鲁帕妥单抗BAY 1112623；BAY 1112623

    Lupartumab (BAY 1112623) is an anti-LYPD3 (C4.4A) monoclonal antibody that can be used to synthesize antibody-active molecular couplers that can be used to study LYPD3-associated tumor diseases.

    价 格：￥电议型 号：T77412产 地：中国大陆

  • T77124Osocimab奥索西单抗BAY 1213790

    Osocimab (BAY 1213790) is a potent anti-FXIa antibody with a Ki value of 2.4 nM and an EC50 value of 0.2 nM.Osocimab may reduce thrombosis through FXI inhibition.Osocimab is often used as an XI factor inhibitor, has an inhibitory effect on thrombin generation, has an anticoagulant effect, and is used in the study of thromboembolic diseases. Thromboembolic Diseases

    价 格：￥电议型 号：T77124产 地：中国大陆

  • T76672Aprutumab阿普卢妥单抗FGFR-moAb|||FGFR2-TTC|||BAY 1179470

    Aprutumab (BAY 1179470) is a human FGFR2 monoclonal antibody with affinity to FGFR2 isoforms FGFR2-IIIB and FGFR2-IIIC. Aprutumab is commonly used to synthesize antibody-drug conjugates.

    价 格：￥电议型 号：T76672产 地：中国大陆

  • T75825Bay 55-9837 TFA；化合物 Bay 55-9837 TFABay 55-9837 TFA

    Bay 55-9837 TFA, a potent and highly selective VPAC2 agonist with a dissociation constant (Kd) of 0.65 nM, represents a potential research therapy for type 2 diabetes [1].

    价 格：￥电议型 号：T75825产 地：中国大陆

  • T75137BAY-747；化合物 BAY-747BAY-747

    BAY-747 (BAY 1165747) is an orally administered, brain-penetrant compound that stimulates soluble guanylate cyclase (sGC). It effectively counteracts memory impairments induced by L-NAME and improves cognitive performance in rats during the object location task (OLT). Additionally, BAY-747 reduces blood pressure in conscious normotensive and spontaneously hypertensive rats (SHR) and enhances skeletal muscle function in the mdx/mTRG2 mouse model of Duchenne muscular dystrophy (DMD) [1] [2] [3].

    价 格：￥电议型 号：T75137产 地：中国大陆

  • T75101BAY-728；化合物 BAY-728BAY-728

    BAY-728 serves as a negative control for BAY-805, a potent and selective inhibitor of USP21 [1].

    价 格：￥电议型 号：T75101产 地：中国大陆

  • T74213BAY-6672 hydrochloride；化合物 BAY-6672 hydrochlorideBAY-6672 hydrochloride

    BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.

    价 格：￥电议型 号：T74213产 地：中国大陆

  • T7403BAY-598；化合物BAY-598BAY-598

    BAY-598 is a selective inhibitor of SMYD2 with IC50 values of 27 nM.

    价 格：￥电议型 号：T7403产 地：中国大陆

  • T73461BAY-805；BAY-805BAY-805

    BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21 . BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymes [1] .

    价 格：￥电议型 号：T73461产 地：中国大陆

  • T73451BAY-364；化合物 BAY-364BAY-299N；BAY-299N

    BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+ cells, and K562 cells with respective IC50 values of 1.0 ?M, 10.4 ?M, and 10.0 ?M.

    价 格：￥电议型 号：T73451产 地：中国大陆

  • T73432BAY-390；化合物 BAY-390BAY-390

    BAY-390 is a brain-penetrating, species-agnostic inhibitor of TRPA1, exhibiting selective inhibition of human and rat TRPA1 with IC50 values of 16 nM for hTRPA1 FLIPR, 82 nM for hTRPA1 Ephys, 63 nM for rTRPA1 FLIPR, and 35 nM for rDRG Ephys. It holds potential for inflammation research applications.

    价 格：￥电议型 号：T73432产 地：中国大陆

  • T73394BAY-7081；化合物 BAY-7081BAY-7081

    BAY-7081 is a cyanopyridone-based compound that functions as a potent, selective, and orally active PDE9A inhibitor, demonstrating an inhibition concentration (IC 50) of 15 nM. It exhibits solubility in oral formulations.

    价 格：￥电议型 号：T73394产 地：中国大陆

  • T73371BAY-3153；化合物 BAY-3153BAY-3153

    BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) [1] .

    价 格：￥电议型 号：T73371产 地：中国大陆

  • T73350BAY-3827；化合物 BAY-3827BAY-3827

    BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer model. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.

    价 格：￥电议型 号：T73350产 地：中国大陆

  • T7318Elimusertib；化合物BAY-1895344BAY-1895344；BAY-1895344

    Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride.

    价 格：￥电议型 号：T7318产 地：中国大陆

  • T7315BAY1125976；化合物BAY1125976BAY1125976

    BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)

    价 格：￥电议型 号：T7315产 地：中国大陆

  • T73053BAY 2965501；化合物BAY 2965501BAY 2965501

    BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer.

    价 格：￥电议型 号：T73053产 地：中国大陆

  • T72990BAY 1214784；化合物 BAY 1214784BAY 1214784

    BAY 1214784, a potent, selective, and orally active spiroindoline derivative compound, serves as an antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). It notably reduces plasma luteinizing hormone levels by up to 49%, demonstrating low pharmacokinetic variability and good tolerability. This compound shows promise for research into uterine fibroids.

    价 格：￥电议型 号：T72990产 地：中国大陆

  • T72519Niclosamide sodium；化合物 Niclosamide sodiumBAY2353 sodium；BAY2353 sodium

    Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 μM in HeLa cells. Additionally, this compound exhibits significant biological activities against cancer and effectively inhibits DNA replication in Vero E6 cells.

    价 格：￥电议型 号：T72519产 地：中国大陆

  • T7201Nelociguat；化合物NelociguatBAY60-4552；N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯|||B

    Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.

    价 格：￥电议型 号：T7201产 地：中国大陆

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