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T63265EGFR-IN-36;化合物 EGFR-IN-36EGFR-IN-36
EGFR-IN-36 is a potent inhibitor of EGFR, capable of acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), HER2 (A775_G776insYVMA) (IC50: 2.35 nM). EGFR-IN-36 exhibits the potential to study wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.
价 格:¥电议型 号:T63265产 地:中国大陆
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T63264EGFR-IN-33;化合物 EGFR-IN-33EGFR-IN-33
EGFR-IN-33, an acrylamide derivative, is a low-toxicity antitumor agent and a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 exhibits potential for the study of EGFR mutation-related diseases.
价 格:¥电议型 号:T63264产 地:中国大陆
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T63189EGFR/BRAF-IN-1;化合物 EGFR/BRAF-IN-1EGFR/BRAF-IN-1
EGFR/BRAF-IN-1, a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent inhibitor of EGFR/BRAF, inhibiting BRAFV600E (IC50:45 nM) and cancer cell proliferation (GI50=35 nM), with good antioxidant effect.
价 格:¥电议型 号:T63189产 地:中国大陆
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T63185EGFR-IN-47;化合物 EGFR-IN-47EGFR-IN-47
EGFR-IN-47 is a potent, orally active inhibitor of EGFRL858R/T790M/C797S (IC50: 0.01 μM). EGFR-IN-47 is capable of blocking the cell cycle and inducing apoptosis. EGFR-IN-47 has potential for NSCLC studies.
价 格:¥电议型 号:T63185产 地:中国大陆
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T63178EGFR-IN-39;化合物 EGFR-IN-39EGFR-IN-39
EGFR-IN-39, an acrylamide derivative, is a potent inhibitor of EGFR. EGFR-IN-39 is an antitumor agent with low toxicity and side effects. Among them, the overexpression and mutation of epidermal growth factor receptor (EGFR) have been clearly confirmed to cause uncontrollable cell growth, and are related to the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 has the potential to study EGFR mutation-related diseases.
价 格:¥电议型 号:T63178产 地:中国大陆
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T63168VEGFR-2-IN-26;化合物 VEGFR-2-IN-26VEGFR-2-IN-26
VEGFR-2-IN-26 (compound 5h) is a potent inhibitor of VEGFR-2 (IC50: 15.5 nM).VEGFR-2-IN-26 exhibits good anti-proliferative effects on leukaemia, CNS, non-small lung, ovarian, renal, prostate and breast cancer cells.
价 格:¥电议型 号:T63168产 地:中国大陆
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T63161EGFR/HER2/CDK9-IN-3;化合物 EGFR/HER2/CDK9-IN-3EGFR/HER2/CDK9-IN-3
EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR (IC50:191.08 nM), HER2 (IC50:132.65 nM), and CDK9 (IC50:113.98 nM). EGFR/HER2/CDK9-IN-3 showed significant anti-tumor effects.
价 格:¥电议型 号:T63161产 地:中国大陆
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T63112VEGFR-IN-3;化合物 VEGFR-IN-3VEGFR-IN-3
VEGFR-IN-3 (compound 3f), a VEGFR inhibitor, exhibits potent anticancer activity by inhibiting the growth of OVCAR-4 and MDA-MB-468 cancer cells with IC50 values of 0.29 and 0.35 μM, respectively. It has potential applications in cancer research [1].
价 格:¥电议型 号:T63112产 地:中国大陆
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T63070EGFR-IN-45;化合物 EGFR-IN-45EGFR-IN-45
EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR), acting on EGFR (IC50: 0.4 μM) and CDK2 (IC50: 1.6 μM). EGFR-IN-45 also inhibits the topoisomerases Topo I and Topo II. EGFR-IN-45 blocks the cell cycle of cancer cells in the pre-G1 phase and induces apoptosis.
价 格:¥电议型 号:T63070产 地:中国大陆
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T63002VEGFR-2-IN-15;化合物 VEGFR-2-IN-15VEGFR-2-IN-15
VEGFR-2-IN-15 (Compound 14b) is a potent inhibitor of VEGFR-2. VEGFR-2-IN-15 inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.
价 格:¥电议型 号:T63002产 地:中国大陆
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T62901VEGFR-2-IN-27;化合物 VEGFR-2-IN-27VEGFR-2-IN-27
VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.
价 格:¥电议型 号:T62901产 地:中国大陆
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T62796VEGFR-2-IN-13;化合物 VEGFR-2-IN-13VEGFR-2-IN-13
VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor (IC50: 3.4 nM). vEGFR-2-IN-13 arrests the HepG2 cell cycle in G2/M phase and induces apoptosis.
价 格:¥电议型 号:T62796产 地:中国大陆
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T62777EGFR/HER2-IN-3;化合物 EGFR/HER2-IN-3EGFR/HER2-IN-3
EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual EGFR and HER2 inhibitor.
价 格:¥电议型 号:T62777产 地:中国大陆
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T62776EGFR/HER2-IN-2;化合物 EGFR/HER2-IN-2EGFR/HER2-IN-2
EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).
价 格:¥电议型 号:T62776产 地:中国大陆
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T62763VEGFR-2-IN-12;化合物 VEGFR-2-IN-12VEGFR-2-IN-12
VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent inhibitor of VEGFR-2 (IC50: 0.037 μM). VEGFR-2-IN-12 has anti-tumour effects.
价 格:¥电议型 号:T62763产 地:中国大陆
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T62746EGFR/HER2/CDK9-IN-1;化合物 EGFR/HER2/CDK9-IN-1EGFR/HER2/CDK9-IN-1
EGFR/HER2/CDK9-IN-1 (Compound 4) is a potent EGFR/HER2/CDK9 inhibitor with IC50 values of 90.17, 131.39 and 67.04 nM. EGFR/HER2/CDK9-IN-1 exhibits significant anti-tumour effects.
价 格:¥电议型 号:T62746产 地:中国大陆
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T62503EGFR/BRAFV600E-IN-1;化合物 EGFR/BRAFV600E-IN-1EGFR/BRAFV600E-IN-1
EGFR/BRAFV600E-IN-1 (Compound 23) is a potent dual inhibitor of EGFR (IC50: 0.08 μM) and BRAFV600E (IC50: 0.15 μM). EGFR/BRAFV600E-IN-1 exhibited anti-proliferative effects on A-549 (IC50: 1.2 μM), MCF-7 (IC50: 0.79 μM), Panc-1 (IC50: 1.3 μM), HT-29 (IC50: 1.23 μM).
价 格:¥电议型 号:T62503产 地:中国大陆
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T62458EGFR-IN-56;化合物 EGFR-IN-56EGFR-IN-56
EGFR-IN-56 (Compound 13a) is a potent inhibitor of EGFR, acting on EGFRT790M (IC50: 541.7 nM) and EGFRT790M/L858R (IC50: 132.1 nM). EGFR-IN-56 blocks the cell cycle of cancer cells in the G2/M phase and induces EGFR-IN-56 blocks the G2/M phase of the cancer cell cycle and induces apoptosis.
价 格:¥电议型 号:T62458产 地:中国大陆
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T62457EGFR-IN-54;化合物 EGFR-IN-54EGFR-IN-54
EGFR-IN-54 (Compound 3c) is a potent inhibitor of EGFR (IC50: 1.623 μM) and is toxic to cancer cells.
价 格:¥电议型 号:T62457产 地:中国大陆
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T62439VEGFR-2-IN-14;化合物 VEGFR-2-IN-14VEGFR-2-IN-14
VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.
价 格:¥电议型 号:T62439产 地:中国大陆