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T63857EGFR-IN-24;化合物 EGFR-IN-24EGFR-IN-24
EGFR-IN-24 is a potent inhibitor of EGFR and inhibits EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S).
价 格:¥电议型 号:T63857产 地:中国大陆
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T63822VEGFR-2-IN-22;化合物 VEGFR-2-IN-22VEGFR-2-IN-22
VEGFR-2-IN-22 (Compound 25) is an inhibitor of VEGFR-2 and β-tubulin polymerization with an IC50=19.82 nM for VEGFR-2. VEGFR-2-IN-22 is capable of inducing apoptosis.
价 格:¥电议型 号:T63822产 地:中国大陆
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T63804VEGFR-2-IN-28;化合物 VEGFR-2-IN-28VEGFR-2-IN-28
VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.
价 格:¥电议型 号:T63804产 地:中国大陆
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T63798EGFR-IN-32;化合物 EGFR-IN-32EGFR-IN-32
EGFR-IN-32 is a potent inhibitor of EGFR. EGFR-IN-32 has shown research potential for EGFR mutation-related diseases.
价 格:¥电议型 号:T63798产 地:中国大陆
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T63784EGFR-IN-44;化合物 EGFR-IN-44EGFR-IN-44
EGFR-IN-44 is a potent, orally active inhibitor of EGFRtyrosine kinase (IC50: 4.11 nM). EGFR-IN-44 has an oral bioavailability of 33.57% and induces apoptosis. EGFR-IN-44 can be used to study non-small cell lung cancer.
价 格:¥电议型 号:T63784产 地:中国大陆
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T63774EGFR-IN-58;化合物 EGFR-IN-58EGFR-IN-58
EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.
价 格:¥电议型 号:T63774产 地:中国大陆
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T63769EGFR-IN-60;化合物 EGFR-IN-60EGFR-IN-60
EGFR-IN-60 is an effective, orally active, safe antitumor agent. EGFR-IN-60 significantly inhibits EGFRWT (IC50: 83 nM), EGFRT790M (IC50: 26 nM), EGFRL858R (IC50: 53 nM) and JAK3 (IC50: 69 nM). IN-60 inhibited H1975 cells carrying the EGFRT790M mutation (IC50: 1.32 μM) and A431 cells overexpressing EGFRWT (IC50: 4.96 μM). EGFR-IN-60 increased the Bax/Bcl-2 ratio, which induced apoptosis induction and cell death.
价 格:¥电议型 号:T63769产 地:中国大陆
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T63732EGFR-IN-3;EGFR 抑制剂 3EGFR-IN-3
EGFR-IN-3 is an EGFR inhibitor with potential antitumour activity.EGFR-IN-3 inhibits EGFRwt-TK and induces apoptosis (cell death), which can cause cells to block in the G2/M phase.
价 格:¥电议型 号:T63732产 地:中国大陆
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T63722VEGFR-2-IN-24;化合物 VEGFR-2-IN-24VEGFR-2-IN-24
VEGFR-2-IN-24 is a potent inhibitor of VEGFR-2 (IC50: 0.22 μM) and can be used to study tumors.
价 格:¥电议型 号:T63722产 地:中国大陆
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T63693EGFR-IN-55;化合物 EGFR-IN-55EGFR-IN-55
EGFR-IN-55 is a potent inhibitor of EGFR, acting on EGFRWT (IC50: 70 nM) and EGFRL858R/T790M (IC50: 3.9 nM). EGFR-IN-55 was able to block the cell cycle of NCI-H1975 cells in G0/G1 phase, exhibiting anticancer effects.
价 格:¥电议型 号:T63693产 地:中国大陆
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T63648EGFR kinase inhibitor 1;化合物 EGFR kinase inhibitor 1EGFR kinase inhibitor 1
EGFR kinase inhibitor 1 is a potent inhibitor of EGFR that acts on WT (IC50: 37 nM), l885R/T790M (IC50: 1.7 nM), and L858R/T790M/C797S (IC50>300 nM). EGFR kinase inhibitor 1 is capable of blocking the cell cycle in G0/G1 phase, inducing apoptosis, and showing an inhibitory effect on cell metastasis. EGFR kinase inhibitor 1 exhibits anti-proliferative and anti-tumor effects.
价 格:¥电议型 号:T63648产 地:中国大陆
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T63571EGFR-IN-26;化合物 EGFR-IN-26EGFR-IN-26
EGFR-IN-26 is an EGFR inhibitor that can be used in cancer research.
价 格:¥电议型 号:T63571产 地:中国大陆
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T63556EGFR-IN-59;化合物 EGFR-IN-59EGFR-IN-59
EGFR-IN-59 is an EGFR inhibitor with an IC50 value of 190 nM and an all-time apoptosis inducer. EGFR-IN-59 exhibited cytotoxicity against a non-small lung cancer cell line (A549) and normal lung fibroblasts (WI38) with IC50s of 8.62 and 52.6 μM, respectively. EGFR-IN-59 EGFR-IN-59 can be used to study a variety of cancers including non-small cell lung cancer (NSCLC), head and neck cancer, breast cancer and colorectal cancer.
价 格:¥电议型 号:T63556产 地:中国大陆
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T63532EGFR/HER2/TS-IN-2;化合物 EGFR/HER2/TS-IN-2EGFR/HER2/TS-IN-2
EGFR/HER2/TS-IN-2 is a potent inhibitor of EGFR (IC50: 0.173 μM), HER2 (IC50: 0.125 μM) and TS (IC50: 1.12 μM). EGFR/HER2/TS-IN-2 exhibited cytotoxic effects on MDA-MB-231 cancer cells (IC50: 1.69 μM ).
价 格:¥电议型 号:T63532产 地:中国大陆
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T63431EGFR-IN-46;化合物 EGFR-IN-46EGFR-IN-46
EGFR-IN-46 is a potent dual inhibitor of EGFR (IC50: 20.17 nM) and FAK (IC50: 14.25 nM) that significantly inhibits the growth of cancer cells and induces apoptosis.
价 格:¥电议型 号:T63431产 地:中国大陆
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T63401EGFR/HER2/TS-IN-1;化合物 EGFR/HER2/TS-IN-1EGFR/HER2/TS-IN-1
EGFR/HER2/TS-IN-1 are EGFR, HER2 and TS (Thymidylate synthase) inhibitors with IC50 values of 0.203, 0.088 and 0.168 μM, respectively, and have the ability to induce apoptosis (MCF7 cell death).
价 格:¥电议型 号:T63401产 地:中国大陆
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T63357EGFR/HER2/CDK9-IN-2;化合物 EGFR/HER2/CDK9-IN-2EGFR/HER2/CDK9-IN-2
EGFR/HER2/CDK9-IN-2 are potent inhibitors of EGFR/HER2/CDK9, and they exhibited significant antitumor effects with IC50s of 145.35, 129.07 and 117.13 nM, respectively.
价 格:¥电议型 号:T63357产 地:中国大陆
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T63300EGFR-IN-34;化合物 EGFR-IN-34EGFR-IN-34
EGFR-IN-34 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-34 exhibits potential for research in EGFR mutation-related diseases.
价 格:¥电议型 号:T63300产 地:中国大陆
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T63283EGFR-IN-38;化合物 EGFR-IN-38EGFR-IN-38
EGFR-IN-38 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-38 exhibits potential for research in EGFR mutation-related diseases.
价 格:¥电议型 号:T63283产 地:中国大陆
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T63282EGFR-IN-35;化合物 EGFR-IN-35EGFR-IN-35
EGFR-IN-35 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-35 exhibits potential for investigation of EGFR mutation-related diseases.
价 格:¥电议型 号:T63282产 地:中国大陆