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T29109VPC12249;化合物 T29109VPC-12249|||VPC 12249;VPC-12249|||VPC 12249
VPC12249, a lysophosphatidic acid receptor type 1 (LPA1) antagonist, plays a functional role in osteoclast differentiation and bone resorption activity.
价 格:¥电议型 号:T29109产 地:中国大陆
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T28851SRA880 free base;化合物 T28851SRA 880|||NVPSRA880|||NVP SRA880|||NVP-SRA880|||SRA-880|||SRA880;SRA 880|
SRA880 is a non-peptide antagonist of somatostatin sst1-receptor. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0). SRA880 shows a certain binding affinity to the human dopamine D4 receptors. SRA880 positively modulates release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.
价 格:¥电议型 号:T28851产 地:中国大陆
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T28256OPC-14523 free base;化合物 T28256OPC 14523|||VPI013|||VPI-013|||OPC14523|||OPC-14523|||VPI 013;OPC 1452
OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.
价 格:¥电议型 号:T28256产 地:中国大陆
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T28221NVP-QAV-680;化合物 T28221NVPQAV680|||NVP-QAV 680|||NVP-QAV680|||NVP-QAV680|||NVP QAV 680|||QAV690 free
NVP-QAV-680 is a potent and selective antagonist of CRTh2 receptor. NVP-QAV-680 has nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.
价 格:¥电议型 号:T28221产 地:中国大陆
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T27802LBM-415;化合物 T27802NVP-PDF-713;NVP-PDF-713
LBM-415 is a peptide deformylase (PDF) inhibitor.
价 格:¥电议型 号:T27802产 地:中国大陆
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T2680NVP-BVU972;化合物NVP-BVU972NVP-BVU972
NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.
价 格:¥电议型 号:T2680产 地:中国大陆
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T26685AUY954 HCl;化合物 T26685NVP-AUY954|||AUY 954|||AUY954 hydrochloride|||AUY-954|||AUY954;NVP-AUY954|||AUY
AUY-954 is a potent and selective S1P(1) modulator. AUY-954 prevents experimental autoimmune neuritis in rats.
价 格:¥电议型 号:T26685产 地:中国大陆
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T26631LAnidoxime HCl;阿尼多昔盐酸盐USVP-E142|||Anidoxime HCl( 34297-34-2 Free base);USVP-E142|||Anidoxime HCl( 3
Anidoxime HCl (USVP-E142) is a novel orally available compound with anti-analgesic activity.
价 格:¥电议型 号:T26631L产 地:中国大陆
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T26323VPC-3033;化合物 T26323VPC-3033
VPC-3033 is an antagonist of the androgen receptor. It acts by inhibiting the LNCaP cell line as well as cell lines with the wild-type androgen receptor.
价 格:¥电议型 号:T26323产 地:中国大陆
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T26225SRA880 malonate;化合物 T26225SRA880|||NVPSRA880|||NVP-SRA880|||NVP-SRA-880|||NVP-SRA 880|||NVP SRA880;S
SRA880 is a non-peptide somatostatin sst(1) receptor antagonist which displays a significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d)= 6.0) or a wide range of neurotransmitter receptors, except for the human dopamine D4 receptors. SRA880 positively modulates the release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.
价 格:¥电议型 号:T26225产 地:中国大陆
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T2618LGK974;化合物LGK-974LGK 974|||LGK-974|||NVP-LGK974|||WNT974;LGK 974|||LGK-974|||NVP-LGK974|||WNT974
LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
价 格:¥电议型 号:T2618产 地:中国大陆
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T25895NVP-SAA164;化合物 T25895SAA 164|||SAA164|||SAA-164|||NVP SAA164;SAA 164|||SAA164|||SAA-164|||NVP SAA164
NVP-SAA164 is a nonpeptide bradykinin B1 receptor antagonist agent.
价 格:¥电议型 号:T25895产 地:中国大陆
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T25894NVP-AAD777;化合物 T25894AAD-777|||NVP-AAD-777|||NVP AAD 777;AAD-777|||NVP-AAD-777|||NVP AAD 777
NVP-AAD777 is a specific VEGFR-2 inhibitor.
价 格:¥电议型 号:T25894产 地:中国大陆
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T24944VPC-14449;化合物 T24944VPC14449|||VPC 14449;VPC14449|||VPC 14449
VPC-14449 is a specific inhibitor of AR-DBD that acts by inhibiting both Y594A and Q592A mutants.
价 格:¥电议型 号:T24944产 地:中国大陆
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T24943VPC-14228;化合物VPC-14228VPC 14228|||VPC14228;VPC 14228|||VPC14228
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
价 格:¥电议型 号:T24943产 地:中国大陆
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T24564NVP-ABJ688;化合物 T24564ABJ-688|||ABJ 688|||ABJ688;ABJ-688|||ABJ 688|||ABJ688
NVP-ABJ688 is the cysteine protease cathepsin K inhibitor.
价 格:¥电议型 号:T24564产 地:中国大陆
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T2454Dacinostat;达西司特NVP-LAQ824|||LAQ824;NVP-LAQ824|||达西司特|||LAQ824
LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
价 格:¥电议型 号:T2454产 地:中国大陆
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T2383Panobinostat;帕比司他NVP-LBH589|||LBH589;帕比司他|||NVP-LBH589|||LBH589
Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity. Panobinostat has antitumor activity and induces apoptosis and autophagy.
价 格:¥电议型 号:T2383产 地:中国大陆
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T2285Encenicline hydrochloride;化合物EVP-6124 hydrochlorideEVP-6124 (hydrochloride)|||EVP-6124 hydrochloride
Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
价 格:¥电议型 号:T2285产 地:中国大陆
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T2251NVP-TAE 684;化合物TAE684TAE684;TAE684|||5-氯-N2-[2-甲氧基-4-[4-(4-甲基-1-哌嗪基)-1-哌啶基]苯基]-N4-[2-[(1-甲基乙基)磺酰基]苯基
NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).
价 格:¥电议型 号:T2251产 地:中国大陆