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T7193Encenicline;化合物EnceniclineEVP-6124;EVP-6124
Encenicline (EVP-6124) is a selective α7 nicotinic acetylcholine receptor (nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer´s disease.
价 格:¥电议型 号:T7193产 地:中国大陆
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T70992NVP-CFC218;化合物 NVP-CFC218NVP-CFC218
NVP-CFC218 is a novel potent and selective p53-HDM2 inhibitor.
价 格:¥电议型 号:T70992产 地:中国大陆
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T70789VPC03090;化合物 VPC03090VPC03090
VPC03090 is a Sphingosine-1-Phosphate Receptor Inhibitor. VPC03090 is an analog of FTY-720, acts as antagonist for S1PR1 and S1PR3. VPC03090-P, converted from VPC03090 through the phosphorylation by SK-2, causes a reduction in tumor growth in mice with mammary cancer, and its oral bioavailability is determined to be 30 hours.
价 格:¥电议型 号:T70789产 地:中国大陆
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T70760NVP018;化合物 NVP018NVP018
NVP018, also known as BC 556, is a potent inhibitor of hepatitis B virus, hepatitis C virus (HCV), and HIV-1 replication, shows minimal inhibition of major drug transporters, and has a high barrier to generation of both HCV and HIV-1 resistance..
价 格:¥电议型 号:T70760产 地:中国大陆
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T7064Valproic Acid丙戊酸Sodium valproate|||2-Propylpentanoic Acid|||丙戊酸|||VPA|||Depakine|||2-Propylvaleric A
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
价 格:¥电议型 号:T7064产 地:中国大陆
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T70182NVP-BHS345;化合物 NVP-BHS345NVP-BHS345
NVP-BHS345 is a dual inhibitor of TORC1 and TORC2.
价 格:¥电议型 号:T70182产 地:中国大陆
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T7015Vps34-IN-1;化合物VPS34-IN1VPS34-IN1;VPS34-IN1
Vps34-IN-1 (VPS34-IN1) is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM in vitro, which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.
价 格:¥电议型 号:T7015产 地:中国大陆
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T69982VPC-16606;化合物 VPC-16606VPC-16606
VPC-16606 is a potent and selective inhibitor of ERα-dependent cell growth and gene expression. VPC-16606 prevents the interaction between ERα-LBD and SRC-3 fusion proteins in a dose-dependent manner.
价 格:¥电议型 号:T69982产 地:中国大陆
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T6962Rasagiline Mesylate;甲磺酸雷沙吉兰TVP1012|||AGN1135|||Azilect;TVP1012|||甲磺酸雷沙吉兰|||AGN1135|||Azilect
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson´s disease.
价 格:¥电议型 号:T6962产 地:中国大陆
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T6945Vps34-PIK-III;化合物PIK-IIIPIK-III|||VPS34-IN2;PIK-III|||VPS34-IN2
Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.
价 格:¥电议型 号:T6945产 地:中国大陆
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T68740NVP-TAC544;化合物 NVP-TAC544NVP-TAC544
NVP-TAC544 is a novel focal adhesion kinase (FAK) inhibitor, potently blocking kinase activity of FAK along with Aurora A, activated Cdc42-associated kinase 1 (ACK1), Met, insulin receptor (IR), TrkA, and IGF-1R.
价 格:¥电议型 号:T68740产 地:中国大陆
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T68698VPC 23153;化合物 VPC 23153VPC 23153
VPC 23153 is a sphingosine 1-phosphate 4 receptor agonist. This hygroscopic phospholipid causes contraction of pulmonary artries in rats.
价 格:¥电议型 号:T68698产 地:中国大陆
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T68679VPC 32183 (S);化合物 VPC 32183 (S)VPC 32183 (S)
VPC 32183 (S) is a competitive antagonist at the LPA1 and LPA3 receptors. VPC 32183 is devoid of agonist activity at the human LPA1, LPA2 and LPA3 receptors, and, presumably, at other mammalian LPA receptors.
价 格:¥电议型 号:T68679产 地:中国大陆
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T68678VPC 24191;化合物 VPC 24191VPC 24191
VPC 24191 is a sphingosine 1-phosphate (S1P1/3) receptor agonist.
价 格:¥电议型 号:T68678产 地:中国大陆
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T64316VP-4604;化合物VP-46041-((4-Nitrophenyl)sulfonyl)piperidine;1-((4-Nitrophenyl)sulfonyl)piperidine
VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL. VP-4604 inhibited the growth of methicillin-resistant S. aureus with a growth inhibition rate of over 95%.
价 格:¥电议型 号:T64316产 地:中国大陆
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T64315VP-4509;化合物 VP-4509VP-4509
VP-4509 is an anti-methicillin-resistant Staphylococcus aureus (MRSA) agent (MIC: 49.3 μM). VP-4509 exhibits high antibacterial activity against the gram-negative bacterium Pseudomonas aeruginosa (ATCC9027).
价 格:¥电议型 号:T64315产 地:中国大陆
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T6348NVP-BHG712;化合物NVP-BHG712NVP-BHG712
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
价 格:¥电议型 号:T6348产 地:中国大陆
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T6294NVP-BSK805 2HCl (1092499-93-8(free base));化合物NVP-BSK805 2HClNVP-BSK805 dihydrochloride|||BSK 805|||N
NVP-BSK805 2HCl (1092499-93-8(free base)) (BSK 805)(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
价 格:¥电议型 号:T6294产 地:中国大陆
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T62816NVP-CLR457;化合物 NVP-CLR457NVP-CLR457
NVP-CLR457 (compound 40) is an orally active, balanced, pan-class I PI3K inhibitor with antitumour effects.NVP-CLR457 exhibits a significant dose-dependent PK/PD/efficacy relationship.
价 格:¥电议型 号:T62816产 地:中国大陆